Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Seema Khattri Bhandari"'
Autor:
Seema Khattri Bhandari, Nathaniel Wiest, Annahita Sallmyr, Ruofei Du, Laure Ferry, Pierre-Antoine Defossez, Alan E. Tomkinson
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract DNA ligase I (LigI), the predominant enzyme that joins Okazaki fragments, interacts with PCNA and Pol δ. LigI also interacts with UHRF1, linking Okazaki fragment joining with DNA maintenance methylation. Okazaki fragments can also be joined
Externí odkaz:
https://doaj.org/article/3144e10f780c4a7b930dcc25e9019c23
Publikováno v:
Mutagenesis
The joining of interruptions in the phosphodiester backbone of DNA is critical to maintain genome stability. These breaks, which are generated as part of normal DNA transactions, such as DNA replication, V(D)J recombination and meiotic recombination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ee262aef5d5ef0fd2ae255a6068b7f6
https://doi.org/10.1093/mutage/gez026
https://doi.org/10.1093/mutage/gez026
Publikováno v:
DNA Repair (Amst)
To ensure genome integrity, the joining of breaks in the phosphodiester backbone of duplex DNA is required during DNA replication and to complete the repair of almost all types of DNA damage. In human cells, this task is accomplished by DNA ligases e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e94d925926b6fe3c433382b99369b067
https://pubmed.ncbi.nlm.nih.gov/33087274
https://pubmed.ncbi.nlm.nih.gov/33087274