Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Seema Dangwal"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 4895-4913 (2023)
In the fast-evolving landscape of biomedical research, the emergence of big data has presented researchers with extraordinary opportunities to explore biological complexities. In biomedical research, big data imply also a big responsibility. This is
Externí odkaz:
https://doaj.org/article/7fa14dc1c5dc413c885c9ffabf86fd84
Autor:
Ariana Foinquinos, Sandor Batkai, Celina Genschel, Janika Viereck, Steffen Rump, Mariann Gyöngyösi, Denise Traxler, Martin Riesenhuber, Andreas Spannbauer, Dominika Lukovic, Natalie Weber, Katrin Zlabinger, Ena Hašimbegović, Johannes Winkler, Jan Fiedler, Seema Dangwal, Martin Fischer, Jeanne de la Roche, Daniel Wojciechowski, Theresia Kraft, Rita Garamvölgyi, Sonja Neitzel, Shambhabi Chatterjee, Xiaoke Yin, Christian Bär, Manuel Mayr, Ke Xiao, Thomas Thum
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
miR-132 was shown to drive pathological cardiac remodeling, a hallmark of heart failure. Here, the authors show that an antisense inhibitor of miR-132 has favourable pharmacokinetics, safety-tolerability and preclinical efficacy in mouse and porcine
Externí odkaz:
https://doaj.org/article/33579ddb7f504de8ad9792e4fd12c4d2
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2440 (2022)
Since ancient times aging has also been regarded as a disease, and humankind has always strived to extend the natural lifespan. Analyzing the genes involved in aging and disease allows for finding important indicators and biological markers for patho
Externí odkaz:
https://doaj.org/article/13d9db2e3f1a411abc034a3ae5f50874
Publikováno v:
Cells, Vol 10, Iss 11, p 3112 (2021)
Personalized regenerative medicine and biomedical research have been galvanized and revolutionized by human pluripotent stem cells in combination with recent advances in genomics, artificial intelligence, and genome engineering. More recently, we hav
Externí odkaz:
https://doaj.org/article/52fa32cccbd646dc8d42803f6f5e79a8
Publikováno v:
The Renin Angiotensin System in Cardiovascular Disease ISBN: 9783031149511
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d03574306a003b74d9a759236e47344
https://doi.org/10.1007/978-3-031-14952-8_5
https://doi.org/10.1007/978-3-031-14952-8_5
MicroRNA-21 regulates right ventricular remodeling secondary to pulmonary arterial pressure overload
Autor:
Kevin M. Alexander, Frederick Y. Chen, Jahan Mohebali, Michael Chen, Yiling Qiu, Ronglih Liao, Sudeshna Fisch, Seema Dangwal, Amy G. Fiedler, Wei Ting Chang, Yanfei Yang, Chih Hsin Hsu
Publikováno v:
Journal of Molecular and Cellular Cardiology. 154:106-114
Right ventricular (RV) function is a critical determinant of survival in patients with pulmonary arterial hypertension (PAH). While miR-21 is known to associate with vascular remodeling in small animal models of PAH, its role in RV remodeling in larg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::227a64e80019da3ae502d80b71c5442d
https://doi.org/10.1016/j.yjmcc.2021.01.003
https://doi.org/10.1016/j.yjmcc.2021.01.003
Autor:
Susan Cheng, Michael Chen, Wei-Ting Chang, Sudeshna Fisch, Ronglih Liao, Seema Dangwal, Zhih-Cherng Chen
Publikováno v:
Hypertens Res
Coronary flow velocity (CFV) is reduced in pathologic cardiac hypertrophy. This functional reduction is linked to adverse cardiac remodeling, hypertension and fibrosis, and angiotensin II (AngII) is a key molecular player. Angiotensin receptor blocke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8d6ec6783230bca5fb4c0b795d07be
https://doi.org/10.1038/s41440-021-00617-1
https://doi.org/10.1038/s41440-021-00617-1
Short summaryBiological molecular data such as sequence information increase so rapidly that detailed metadata, describing the process and conditions of data collection as well as proper labelling and typing of the data become ever more important to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dd4dc40a8d95117bc40a318c9b012d0
https://doi.org/10.1101/2021.12.17.473021
https://doi.org/10.1101/2021.12.17.473021
Autor:
Ratnesh Sahay, Seema Dangwal, Ghanshyam Verma, Dietrich Rebholz-Schuhmann, Yasar Khan, Mathieu d'Aquin, Qaiser Mehmood, Durre Zehra, Alokkumar Jha
Publikováno v:
Journal of Advances in Health. :70-84
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45eb368bd764041c0589f296dd747ffe
https://doi.org/10.3724/sp.j.2640-8686.2019.0063
https://doi.org/10.3724/sp.j.2640-8686.2019.0063
Autor:
Shishir K. Gupta, Seema Dangwal, Mugdha Srivastava, Aman Akash, Thomas Dandekar, Rashmi Minocha
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11279, p 11279 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
A viral infection involves entry and replication of viral nucleic acid in a host organism, subsequently leading to biochemical and structural alterations in the host cell. In the case of SARS-CoV-2 viral infection, over-activation of the host immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff926340476089813817673ccf4293d
https://doi.org/10.3390/ijms222011279
https://doi.org/10.3390/ijms222011279