Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Seema Briyal"'
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Centhaquine (CQ) (Lyfaquin®) is in late stage clinical development as a safe and effective first-in-class resuscitative agent for hemorrhagic shock patients (NCT02408731, NCT04056065, and NCT04045327). Acute kidney injury (AKI) is known
Externí odkaz:
https://doaj.org/article/e2186f20ac4641dd9db94d5aeafa48e3
Autor:
Sweatha Kasala, Seema Briyal, Preetha Prazad, Amaresh K. Ranjan, Gospodin Stefanov, Ramona Donovan, Anil Gulati
Publikováno v:
Frontiers in Pediatrics, Vol 8 (2020)
Background: Preterm infants experience rapid brain growth during early post-natal life making them vulnerable to drugs acting on central nervous system. Morphine is administered to premature neonates for pain control and caffeine for apnea of prematu
Externí odkaz:
https://doaj.org/article/828d88343914466faddd6b4e79c1a811
Publikováno v:
Frontiers in Pediatrics, Vol 8 (2020)
Oxidative stress results from excessive reactive oxygen species formation and/or inadequate antioxidant defense. Premature and critically ill infants are especially susceptible due to an immature intrinsic antioxidant system that cannot fully compens
Externí odkaz:
https://doaj.org/article/35075702fc5c44ddb1f1cfb7cc9dd19c
Publikováno v:
Frontiers in Pediatrics, Vol 8 (2020)
Introduction: Neonatal HIE is associated with high morbidity and mortality. Current research, is focused on developing alternative treatments to therapeutic hypothermia for treatment of HIE. The endocannabinoid system is known to be influential in ne
Externí odkaz:
https://doaj.org/article/f7d1d836bd054e89983ca5ffa158ffc9
Publikováno v:
Heliyon, Vol 3, Iss 6, Pp e00317- (2017)
Aim: ETA receptor antagonists reverse opioid tolerance but the involvement of ETB receptors is unknown. In morphine or oxycodone tolerant mice we investigated (1) the effect of ETB receptor agonist, IRL-1620, on analgesic tolerance; (2) changes in ex
Externí odkaz:
https://doaj.org/article/64b4548f2ab34ecdbf8721184b17e8af
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::109673dfa2b47c1ba7ad6224bd4a18be
https://doi.org/10.1002/alz.069330
https://doi.org/10.1002/alz.069330
Publikováno v:
Neurochemistry International. 165:105509
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dab88d8aedbe4c52422f2531589a8f4
https://doi.org/10.1016/j.neuint.2023.105509
https://doi.org/10.1016/j.neuint.2023.105509
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 98:659-666
Stimulation of endothelin B receptors by its agonist IRL-1620 (INN, sovateltide) provides neuroprotection and neurological and motor function improvement following cerebral ischemia. We investigated the effect of sovateltide on stem and progenitor ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::348a877598a1d77588d16e289040f592
https://doi.org/10.1139/cjpp-2020-0164
https://doi.org/10.1139/cjpp-2020-0164
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::186ab43c100b56c264e454b804e31700
https://doi.org/10.1002/alz.057431
https://doi.org/10.1002/alz.057431
Publikováno v:
Circulation. 144
Background: Acute Kidney Injury (AKI) is frequently associated with an in-hospital complication of sepsis, heart conditions, hemorrhagic shock, and surgery. However, at present, no specific drug to treat AKI is available. Centhaquine (Lyfaquin ® ) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51e7d43567055fb0d4286ecde166ab63
https://doi.org/10.1161/circ.144.suppl_1.11322
https://doi.org/10.1161/circ.144.suppl_1.11322