Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Seema Bhat"'
Autor:
Max Yano, Chia Sharpe, J. Rachel Lance, Janani Ravikrishnan, Kevan Zapolnik, Xiaokui Mo, Jennifer A. Woyach, Deepa Sampath, Adam S. Kittai, Sumithira Vasu, Seema Bhat, Kerry A. Rogers, Dean A. Lee, Natarajan Muthusamy, John C. Byrd
Publikováno v:
Blood Advances. 6:5641-5654
Successes with anti-CD20 antibodies in chronic lymphocytic leukemia (CLL) and enhanced activity of Fc-engineered vs unmodified antibody therapy suggest a potentially impactful role for natural killer (NK) cells and other innate immune cells in contro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff7d9c8eee3c64f177101fec5cc3cd6
https://doi.org/10.1182/bloodadvances.2021005883
https://doi.org/10.1182/bloodadvances.2021005883
Autor:
Jennifer A. Woyach, John C. Byrd, Rosa Lapalombella, Hank Lockman, Samantha M. Jaglowski, Seema Bhat, Kerry A. Rogers, Renee Vadeboncoeur, Harsh Shah, Boyu Hu, Sharyn Baker, Qiang Fu, Casey B. Cempre, Daniel Canfield, Janek S. Walker, Amy S. Ruppert, Ying Huang, Deborah M. Stephens
Purpose:Dual blockade of Bruton's tyrosine kinase with ibrutinib and selinexor has potential to deepen responses for patients with chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma (NHL).Patients and Methods:In this phase I study (clinicalt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5473c10baa71f18bffb8e5cd70446661
https://doi.org/10.1158/1078-0432.c.6532472.v1
https://doi.org/10.1158/1078-0432.c.6532472.v1
Autor:
Jennifer A. Woyach, John C. Byrd, Rosa Lapalombella, Hank Lockman, Samantha M. Jaglowski, Seema Bhat, Kerry A. Rogers, Renee Vadeboncoeur, Harsh Shah, Boyu Hu, Sharyn Baker, Qiang Fu, Casey B. Cempre, Daniel Canfield, Janek S. Walker, Amy S. Ruppert, Ying Huang, Deborah M. Stephens
Supplementary Data from Selinexor Combined with Ibrutinib Demonstrates Tolerability and Safety in Advanced B-Cell Malignancies: A Phase I Study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::565e835c784f23a218be444c7afaed07
https://doi.org/10.1158/1078-0432.22487252
https://doi.org/10.1158/1078-0432.22487252
Autor:
Deborah M. Stephens, Ying Huang, Amy S. Ruppert, Janek S. Walker, Daniel Canfield, Casey B. Cempre, Qiang Fu, Sharyn Baker, Boyu Hu, Harsh Shah, Renee Vadeboncoeur, Kerry A. Rogers, Seema Bhat, Samantha M. Jaglowski, Hank Lockman, Rosa Lapalombella, John C. Byrd, Jennifer A. Woyach
Publikováno v:
Clin Cancer Res
Purpose: Dual blockade of Bruton's tyrosine kinase with ibrutinib and selinexor has potential to deepen responses for patients with chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma (NHL). Patients and Methods: In this phase I study (clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bb3abaeb2ff7dd5e988afc9c30a17a8
https://doi.org/10.1158/1078-0432.ccr-21-3867
https://doi.org/10.1158/1078-0432.ccr-21-3867
Publikováno v:
Medical Research Archives. 11
Introduction: Brilaroxazine (RP5063) displays high affinity for serotonin (5-HT) 1A/2A/2B/7 and dopamine (D) 2/3/4 and moderate affinity for D1, serotonin transporter (SERT), and nicotinic acetylcholine receptor, α4β2. These receptors are associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f2b8ab30adc4eea343f103930f450a8
https://doi.org/10.18103/mra.v11i4.3834
https://doi.org/10.18103/mra.v11i4.3834
Autor:
Benjamin Buck, Aaron P. Chum, Mitkumar Patel, Rebecca Carter, Haseeb Nawaz, Vedat Yildiz, Patrick Ruz, Tracy Wiczer, Kerry A. Rogers, Farrukh T. Awan, Seema Bhat, Avirup Guha, Adam S. Kittai, Orlando P. Simonetti, Subha V. Raman, Grant Wallace, Reynaldo Sanchez, Janice M. Bonsu, John Gambril, Devin Haddad, James Mann, Lai Wei, Onaopepo Kola-Kehinde, John C. Byrd, Jennifer A. Woyach, Daniel Addison
Publikováno v:
JAMA Oncology. 9:552
ImportanceIbrutinib has been associated with serious cardiotoxic arrhythmias. In preclinical models, these events are paralleled or proceeded by diffuse myocardial injury (inflammation and fibrosis). Yet whether this is seen in patients or has implic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbbf68ef75df021b5c507dc6b11de83b
https://doi.org/10.1001/jamaoncol.2022.6869
https://doi.org/10.1001/jamaoncol.2022.6869
Autor:
Benjamin Buck, Aaron Chum, Mitkumar Patel, Rebecca R. Carter, Haseeb Nawaz, Vedat Yildiz, Patrick Ruiz, Tracy Wiczer, Kerry Rogers, Farrukh Awan, Seema Bhat, Avirup Guha, Adam Kittai, Orlando P. Simonetti, Subha V. Raman, Grant Wallace, Reynaldo Sanchez, Janice Bonsu, John A. Gambril, Devin Haddad, James Mann, Lai Wei, John Byrd, Jennifer Woyach, Daniel Addison
Publikováno v:
Journal of the American College of Cardiology. 79:1938
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e69a1055c9e9faf906402af05f0e68c3
https://doi.org/10.1016/s0735-1097(22)02929-1
https://doi.org/10.1016/s0735-1097(22)02929-1
Autor:
Jiah Pearson-Leary, Alexander P. Abramenko, Valerie Estela-Pro, Elizabeth Feindt-Scott, Jason Yan, Abigail Vigderman, Sandra Luz, Debra Bangasser, Richard Ross, Leszek Kubin, Seema Bhatnagar
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Dysfunctional fear responses in post-traumatic stress disorder (PTSD) may be partly explained by an inability to effectively extinguish fear responses elicited by trauma-related cues. However, only a subset of individuals exposed to traumati
Externí odkaz:
https://doaj.org/article/d04c2d2f122b4131bee847a14a8ee9d8
Publikováno v:
Neurobiology of Stress, Vol 28, Iss , Pp 100588- (2024)
Psychological stress poses a risk for sleep disturbances. Importantly, trauma-exposed individuals who develop posttraumatic stress disorder (PTSD) frequently report insomnia and recurrent nightmares. Clinical studies have provided insight into the me
Externí odkaz:
https://doaj.org/article/2ea04f6902ff4d2aa57bddb26d3bc630
Autor:
Frederik Denorme, Nicole D. Armstrong, Michelle L. Stoller, Irina Portier, Emilia A. Tugolukova, Rikki M. Tanner, Emilie Montenont, Seema Bhatlekar, Mark Cody, John L. Rustad, Abigail Ajanel, Neal D. Tolley, Darian C. Murray, Julie L. Boyle, Marvin T. Nieman, Steven E. McKenzie, Christian Con Yost, Leslie A. Lange, Mary Cushman, Marguerite R. Irvin, Paul F. Bray, Robert A. Campbell
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 18 (2023)
Protease-activated receptor 4 (PAR4) (gene F2RL3) harbors a functional dimorphism, rs773902 A/G (encoding Thr120/Ala120, respectively) and is associated with greater platelet aggregation. The A allele frequency is more common in Black individuals, an
Externí odkaz:
https://doaj.org/article/d092af6b93764c9897fa3db88dadf434