Zobrazeno 1 - 10 of 2 170 pro vyhledávání: '"Seeliger D"'
1
Akademický článek
Evaluating the use of absolute binding free energy in the fragment optimisation process.
Autor: Alibay I; Department of Biochemistry, The University of Oxford, South Parks Road, OX1 3QU, Oxford, UK., Magarkar A; Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Str. 65, 88397, Biberach an de Riß, Germany., Seeliger D; Boehringer Ingelheim Pharma GmbH & Co. KG, Birkendorfer Str. 65, 88397, Biberach an de Riß, Germany.; Exscientia Inc, Office 400E, 2125 Biscayne Blvd, Miami, FL, 33137, USA., Biggin PC; Department of Biochemistry, The University of Oxford, South Parks Road, OX1 3QU, Oxford, UK. philip.biggin@bioch.ox.ac.uk.
Publikováno v: Communications chemistry [Commun Chem] 2022 Sep 05; Vol. 5 (1), pp. 105. Date of Electronic Publication: 2022 Sep 05.
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2
Akademický článek
ADMET Predictability at Boehringer Ingelheim: State-of-the-Art, and Do Bigger Datasets or Algorithms Make a Difference?
Autor: Aleksić S; Medicinal Chemistry, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397, Biberach, Germany., Seeliger D; Medicinal Chemistry, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397, Biberach, Germany., Brown JB; Medicinal Chemistry, Boehringer Ingelheim Pharma GmbH & Co. KG, 88397, Biberach, Germany.
Publikováno v: Molecular informatics [Mol Inform] 2022 Feb; Vol. 41 (2), pp. e2100113. Date of Electronic Publication: 2021 Sep 02.
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3
Akademický článek
An adapted consensus protein design strategy for identifying globally optimal biotherapeutics.
Autor: Liu Y; Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceutical Inc., Ridgefield, CT, USA., Tsang K; Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceutical Inc., Ridgefield, CT, USA., Mays M; Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceutical Inc., Ridgefield, CT, USA., Hansen G; Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceutical Inc., Ridgefield, CT, USA., Chiecko J; Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceutical Inc., Ridgefield, CT, USA., Crames M; Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceutical Inc., Ridgefield, CT, USA., Wei Y; Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceutical Inc., Ridgefield, CT, USA., Zhou W; Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceutical Inc., Ridgefield, CT, USA., Fredrick C; Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceutical Inc., Ridgefield, CT, USA., Hu J; Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceutical Inc., Ridgefield, CT, USA., Liu D; Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceutical Inc., Ridgefield, CT, USA., Gebhard D; Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceutical Inc., Ridgefield, CT, USA., Huang ZF; Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceutical Inc., Ridgefield, CT, USA., Datar A; Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceutical Inc., Ridgefield, CT, USA., Kronkaitis A; Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceutical Inc., Ridgefield, CT, USA., Gueneva-Boucheva K; Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceutical Inc., Ridgefield, CT, USA., Seeliger D; Medicinal Chemistry, Boehringer Ingelheim Pharma GmbH & Co KG, Biberach, Germany., Han F; Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceutical Inc., Ridgefield, CT, USA., Sen S; Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceutical Inc., Ridgefield, CT, USA., Kasturirangan S; Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceutical Inc., Ridgefield, CT, USA., Scheer JM; Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceutical Inc., Ridgefield, CT, USA., Nixon AE; Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceutical Inc., Ridgefield, CT, USA., Panavas T; Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceutical Inc., Ridgefield, CT, USA., Marlow MS; Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceutical Inc., Ridgefield, CT, USA., Kumar S; Biotherapeutics Discovery, Boehringer Ingelheim Pharmaceutical Inc., Ridgefield, CT, USA.
Publikováno v: MAbs [MAbs] 2022 Jan-Dec; Vol. 14 (1), pp. 2073632.
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4
Akademický článek
A fully human IgG1 antibody targeting connexin 32 extracellular domain blocks CMTX1 hemichannel dysfunction in an in vitro model.
Autor: Tettey-Matey, Abraham1,2 (AUTHOR) abraham.matey@ibbc.cnr.it, Donati, Viola1,3 (AUTHOR) viola.donati@studenti.unipd.it, Cimmino, Chiara4,5 (AUTHOR) chiara.cimmino@ieos.cnr.it, Di Pietro, Chiara1 (AUTHOR) chiara.dipietro@cnr.it, Buratto, Damiano6 (AUTHOR) dburatto@zju.edu.cn, Panarelli, Mariateresa7 (AUTHOR) mariateresa.panarelli@studenti.unipd.it, Reale, Alberto7 (AUTHOR) alberto.reale@unipd.it, Calistri, Arianna7 (AUTHOR) arianna.calistri@unipd.it, Fornaini, Maria Vittoria7 (AUTHOR) mariavittoria.fornaini@phd.unipd.it, Zhou, Ruhong6 (AUTHOR) rhzhou@zju.edu.cn, Yang, Guang8 (AUTHOR) yangguang@shanghaitech.edu.cn, Zonta, Francesco9 (AUTHOR) francesco.zonta@xjtlu.edu.cn, Marazziti, Daniela1 (AUTHOR) daniela.marazziti@cnr.it, Mammano, Fabio1,10 (AUTHOR) fabio.mammano@unipd.it
Publikováno v: Cell Communication & Signaling. 12/5/2024, Vol. 22 Issue 1, p1-18. 18p.
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5
Akademický článek
Cyclophostin and Cyclipostins analogues counteract macrolide-induced resistance mediated by erm(41) in Mycobacterium abscessus.
Autor: Sarrazin, Morgane1 (AUTHOR), Poncin, Isabelle1 (AUTHOR), Fourquet, Patrick2 (AUTHOR), Audebert, Stéphane2 (AUTHOR), Camoin, Luc2 (AUTHOR), Denis, Yann3 (AUTHOR), Santucci, Pierre1 (AUTHOR), Spilling, Christopher D.4 (AUTHOR), Kremer, Laurent5,6 (AUTHOR), Moigne, Vincent Le7 (AUTHOR), Herrmann, Jean-Louis7,8 (AUTHOR), Cavalier, Jean-François1 (AUTHOR), Canaan, Stéphane1 (AUTHOR) canaan@imm.cnrs.fr
Publikováno v: Journal of Biomedical Science. 12/3/2024, Vol. 31 Issue 1, p1-17. 17p.
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6
Akademický článek
Potential mechanism of Qinggong Shoutao pill alleviating age-associated memory decline based on integration strategy.
Autor: Guiyun Pan1,2, Lijuan Chai3, Rui Chen3, Qing Yuan3, Zhihui Song3, Wanying Feng3, Jinna Wei3, Zhihua Yang3, Yuhang Zhang3, Guinan Xie3, An Yan3, Qingbo Lv3, Caijun Wang3, Yingqiang Zhao2,3 zhaoyingqiang1000@126.com, Yi Wang3 wangyi@tjutcm.edu.cn
Publikováno v: Pharmaceutical Biology. Dec2024, Vol. 62 Issue 1, p105-119. 15p.
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7
Akademický článek
Molecular mechanisms underlying Tao-Hong-Si-Wu decoction treating hyperpigmentation based on network pharmacology, Mendelian randomization analysis, and experimental verification.
Autor: Jun Chen1, Wenyi Ye2 yewenyi@zcmu.edu.cn
Publikováno v: Pharmaceutical Biology. Dec2024, Vol. 62 Issue 1, p296-313. 18p.
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9
Akademický článek
Kaempferol alleviates rheumatoid arthritis through pyroptosis based on bioinformatics analysis and experimental validation.
Autor: Ling, Yi1 (AUTHOR), Ren, Nina1 (AUTHOR), Yang, Yuzheng1 (AUTHOR), Xu, Hui2 (AUTHOR), Xiong, Hong1 (AUTHOR), Wang, Qiuyi1 (AUTHOR), Lu, Daomin2 (AUTHOR), Yao, Xueming2 (AUTHOR) yxming19@foxmail.com, Ma, Wukai2 (AUTHOR) walker55@163.com
Publikováno v: Scientific Reports. 11/30/2024, Vol. 14 Issue 1, p1-13. 13p.
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10
Akademický článek
Combinatorial MD/QM studies to develop novel ionic liquid-based anticancer drug delivery systems with aminium derived from carbohydrates as cationic components.
Autor: Kalhor, Sepideh1 (AUTHOR), Fattahi, Alireza1 (AUTHOR) fattahi@sharif.edu
Publikováno v: Scientific Reports. 11/22/2024, Vol. 14 Issue 1, p1-34. 34p.
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