The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin.

Autor: Gunawan M; School of Biological Sciences, College of Science, Nanyang Technological University, Republic of Singapore., Venkatesan N; School of Biological Sciences, College of Science, Nanyang Technological University, Republic of Singapore., Loh JT; School of Biological Sciences, College of Science, Nanyang Technological University, Republic of Singapore., Wong JF; School of Biological Sciences, College of Science, Nanyang Technological University, Republic of Singapore., Berger H; School of Biological Sciences, College of Science, Nanyang Technological University, Republic of Singapore., Neo WH; School of Biological Sciences, College of Science, Nanyang Technological University, Republic of Singapore., Li LY; Singapore Immunology Network, Agency for Science, Technology and Research, Biopolis, Republic of Singapore., La Win MK; School of Biological Sciences, College of Science, Nanyang Technological University, Republic of Singapore., Yau YH; School of Biological Sciences, College of Science, Nanyang Technological University, Republic of Singapore., Guo T; School of Biological Sciences, College of Science, Nanyang Technological University, Republic of Singapore., See PC; Singapore Immunology Network, Agency for Science, Technology and Research, Biopolis, Republic of Singapore., Yamazaki S; Department of immunology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan., Chin KC; 1] Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Republic of Singapore. [2] Institute of Molecular &Cell Biology, Agency for Science and Technology Research, Republic of Singapore., Gingras AR; Department of Medicine, University of California San Diego, La Jolla, California, USA., Shochat SG; School of Biological Sciences, College of Science, Nanyang Technological University, Republic of Singapore., Ng LG; Singapore Immunology Network, Agency for Science, Technology and Research, Biopolis, Republic of Singapore., Sze SK; School of Biological Sciences, College of Science, Nanyang Technological University, Republic of Singapore., Ginhoux F; Singapore Immunology Network, Agency for Science, Technology and Research, Biopolis, Republic of Singapore., Su IH; School of Biological Sciences, College of Science, Nanyang Technological University, Republic of Singapore.

Publikováno v: Nature immunology [Nat Immunol] 2015 May; Vol. 16 (5), pp. 505-16. Date of Electronic Publication: 2015 Mar 09.