Zobrazeno 1 - 10
of 26
pro vyhledávání: '"See Heng Wong"'
Autor:
See Heng Wong1 shwong@mrc-lmb.cam.ac.uk, Barlow, Jillian L.1, Nabarro, Stephen1, Fallon, Padraic G.2, McKenzie, Andrew N. J.1 anm@mrc-lmb.cam.ac.uk
Publikováno v:
Immunology. Sep2010, Vol. 131 Issue 1, p77-88. 12p. 5 Graphs.
Autor:
Neill, Daniel R.1, See Heng Wong1, Bellosi, Agustin1, Flynn, Robin J.1, Daly, Maria1, Langford, Theresa K. A.1, Bucks, Christine2, Kane, Colleen M.2, Fallon, Padraic G.3, Pannell, Richard1, Jolin, Helen E.1, McKenzie, Andrew N. J.1 anm@mrc-lmb.cam.ac.uk
Publikováno v:
Nature. 4/29/2010, Vol. 464 Issue 7293, p1367-1370. 4p. 4 Graphs.
Autor:
Maryam Salimi, James M. Brewer, Emily Hams, See Heng Wong, Graham S. Ogg, Andrew N J McKenzie, Seth T. Scanlon, Jillian L. Barlow, Alexandros Englezakis, Christopher J. Oliphant, Jennifer A. Walker, Padraic G. Fallon, You Yi Hwang
Publikováno v:
Immunity
Summary Group 2 innate lymphoid cells (ILC2s) release interleukin-13 (IL-13) during protective immunity to helminth infection and detrimentally during allergy and asthma. Using two mouse models to deplete ILC2s in vivo, we demonstrate that T helper 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c6fc7ea4d364d5c0795cba7745d1f92
https://doi.org/10.1016/j.immuni.2014.06.016
https://doi.org/10.1016/j.immuni.2014.06.016
Autor:
Padraic G. Fallon, Veera Panova, Ana Camelo, Emily Hams, Clare S. Hardman, Lesley F Drynan, Andrew N J McKenzie, You Yi Hwang, Jillian L. Barlow, Daniel R. Neill, Helen E. Jolin, See Heng Wong, Ute Koch, Jennifer A. Walker, Freddy Radtke
Publikováno v:
Nature immunology
Nuocytes are essential in innate type 2 immunity and contribute to the exacerbation of asthma responses. Here we found that nuocytes arose in the bone marrow and differentiated from common lymphoid progenitors, which indicates they are distinct, prev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bbf8d27e7d1e6d95de9f07eb0b905d2
https://doi.org/10.1038/ni.2208
https://doi.org/10.1038/ni.2208
Publikováno v:
Clinical & Experimental Allergy. 41:1012-1021
Summary Background Initial studies suggested that polymorphisms in Tim1 and Tim3 contribute to the development of airway hyperreactivity (AHR) in an acute mouse model of asthma. This was also mirrored in human genetic studies where polymorphisms in T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1dde24feb4074e5edb16647eb9f0a0f8
https://doi.org/10.1111/j.1365-2222.2011.03728.x
https://doi.org/10.1111/j.1365-2222.2011.03728.x
Autor:
James S. Wainscoat, Luke R Holmes, Alison L Lane, Lesley F Drynan, Jillian L. Barlow, Silvia Lorenzo-Abalde, Alan J. Warren, Richard Pannell, See Heng Wong, Helen E. Jolin, Jacqueline Boultwood, Andrew N. J. McKenzie, Duncan R. Hewett, Angela J Middleton
Publikováno v:
Nature medicine
The identification of the genes associated with chromosomal translocation breakpoints has fundamentally changed understanding of the molecular basis of hematological malignancies. By contrast, the study of chromosomal deletions has been hampered by t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2624f154f731dffcc515adf006ef7491
https://doi.org/10.1038/nm.2063
https://doi.org/10.1038/nm.2063
Autor:
Janet M. Lord, Emma J. Ross, Gerard B. Nash, S. John Curnow, E. Rainger, Ewan A. Ross, Dagmar Scheel-Toellner, Christopher D. Buckley, See Heng Wong, Mike R. Douglas, Mike Salmon
Publikováno v:
Blood. 107:1178-1183
According to the prevailing paradigm, neutrophils are short-lived cells that undergo spontaneous apoptosis within 24 hours of their release from the bone marrow. However, neutrophil survival can be significantly prolonged within inflamed tissue by cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6110002d464e71a5510131987d6c76bc
https://doi.org/10.1182/blood-2005-07-2692
https://doi.org/10.1182/blood-2005-07-2692
Autor:
Rachel Craddock, See Heng Wong, Mike Salmon, Janet M. Lord, Lakhvir K Assi, Keqing Wang, Dagmar Scheel-Toellner, Paul Webb
Publikováno v:
Biochemical Society Transactions. 32:461-464
Neutrophils are very abundant, short-lived leucocytes and their death by apoptosis is central to homoeostasis and the resolution of inflammation, yet the trigger for apoptosis is still a topic of debate. Depolarization of the mitochondrial membrane h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86e6d318413e328a98938a2ab73a7293
https://doi.org/10.1042/bst0320461
https://doi.org/10.1042/bst0320461
Autor:
Arne N. Akbar, Keqing Wang, Jorge Caamano, See Heng Wong, Dagmar Scheel-Toellner, Rachel Craddock, Janet M. Lord, Mike Salmon
Publikováno v:
The Journal of Immunology. 171:1035-1041
Neutrophils are abundant, short-lived leukocytes with a key role in the defense against rapidly dividing bacteria. They enter apoptosis spontaneously within 24–48 h of leaving the bone marrow. However, their life span can be extended during inflamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a57f7291d6476427b7ea8b6084bd9e0f
https://doi.org/10.4049/jimmunol.171.2.1035
https://doi.org/10.4049/jimmunol.171.2.1035
Autor:
Sarah J. Ballantyne, Justin Sprenkle, Keely Wrigley, Andrew N. J. McKenzie, Richard Pannell, Lesley F Drynan, Ana Camelo, See Heng Wong, Daniel R. Neill, Wei Gao, Jillian L. Barlow
Publikováno v:
Journal of Gastroenterology
Background Interleukin-25 (IL-25) is a potent activator of type-2 immune responses. Mucosal inflammation in ulcerative colitis is driven by type-2 cytokines. We have previously shown that a neutralizing anti-IL-25 antibody abrogated airways hyperreac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc7d75df38f8ad1438a56b3fffd4051
https://pubmed.ncbi.nlm.nih.gov/22539101
https://pubmed.ncbi.nlm.nih.gov/22539101