Glycolytic lactate in diabetic kidney disease.

Autor: Darshi M; Center for Precision Medicine, Division of Nephrology, Department of Medicine, University of Texas Health San Antonio, San Antonio, Texas, USA., Kugathasan L; Division of Nephrology, Department of Medicine, University Health Network, Toronto, Canada., Maity S; Center for Precision Medicine, Division of Nephrology, Department of Medicine, University of Texas Health San Antonio, San Antonio, Texas, USA., Sridhar VS; Division of Nephrology, Department of Medicine, University Health Network, Toronto, Canada., Fernandez R; Department of Population Health Sciences, University of Texas Health San Antonio, San Antonio, Texas, USA., Limonte CP; Schools of Medicine and Public Health, University of Washington, Seattle, Washington, USA., Grajeda BI; Department of Biological Sciences and Border Biomedical Research Center, University of Texas at El Paso, El Paso, Texas, USA., Saliba A; Center for Precision Medicine, Division of Nephrology, Department of Medicine, University of Texas Health San Antonio, San Antonio, Texas, USA., Zhang G; Center for Precision Medicine, Division of Nephrology, Department of Medicine, University of Texas Health San Antonio, San Antonio, Texas, USA., Drel VR; Center for Precision Medicine, Division of Nephrology, Department of Medicine, University of Texas Health San Antonio, San Antonio, Texas, USA., Kim JJ; Center for Precision Medicine, Division of Nephrology, Department of Medicine, University of Texas Health San Antonio, San Antonio, Texas, USA., Montellano R; Center for Precision Medicine, Division of Nephrology, Department of Medicine, University of Texas Health San Antonio, San Antonio, Texas, USA., Tumova J; Center for Precision Medicine, Division of Nephrology, Department of Medicine, University of Texas Health San Antonio, San Antonio, Texas, USA., Montemayor D; Center for Precision Medicine, Division of Nephrology, Department of Medicine, University of Texas Health San Antonio, San Antonio, Texas, USA., Wang Z; Department of Population Health Sciences, University of Texas Health San Antonio, San Antonio, Texas, USA., Liu JJ; Clinical Research Unit, Khoo Teck Puat Hospital, Singapore., Wang J; Clinical Research Unit, Khoo Teck Puat Hospital, Singapore., Perkins BA; Division of Nephrology, Department of Medicine, University Health Network, Toronto, Canada., Lytvyn Y; Division of Nephrology, Department of Medicine, University Health Network, Toronto, Canada., Natarajan L; Herbert Wertheim School of Public Health, University of California, San Diego, La Jolla, California USA., Lim SC; Clinical Research Unit & Admiralty Medical Centre, Khoo Teck Puat Hospital, Singapore.; Saw Swee Hock School of Public Heath, National University of Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore., Feldman H; Center for Clinical Epidemiology and Biostatistics and.; Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Toto R; Department of Internal Medicine, University of Texas Southwestern Medical Center, Texas, USA., Sedor JR; Glickman Urology and Kidney and Lerner Research Institutes, Cleveland Clinic, Cleveland, Ohio, USA., Patel J; Department of Internal Medicine, University of Texas Southwestern Medical Center, Texas, USA., Waikar SS; Section of Nephrology, Boston University School of Medicine and Boston Medical Center, Boston, Massachusetts, USA., Brown J; Division of Nephrology, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois, USA., Osman Y; Division of Nephrology, Department of Medicine, Wayne State University, Detroit, Michigan, USA., He J; School of Public Health, Tulane University Medical Center, New Orleans, Louisiana, USA., Chen J; Division of Nephrology, Department of Medicine, New Orleans, Louisiana, USA., Reeves WB; Center for Precision Medicine, Division of Nephrology, Department of Medicine, University of Texas Health San Antonio, San Antonio, Texas, USA., de Boer IH; Schools of Medicine and Public Health, University of Washington, Seattle, Washington, USA., Roy S; Department of Biological Sciences and Border Biomedical Research Center, University of Texas at El Paso, El Paso, Texas, USA., Vallon V; Department of Medicine, University of California, San Diego, La Jolla, California, USA.; VA San Diego Healthcare Center, San Diego, California, USA., Hallan S; Department of Clinical and Molecular Medicine, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Nephrology, St. Olav Hospital, Trondheim, Norway., Gelfond JA; Department of Population Health Sciences, University of Texas Health San Antonio, San Antonio, Texas, USA., Cherney DZ; Division of Nephrology, Department of Medicine, University Health Network, Toronto, Canada., Sharma K; Center for Precision Medicine, Division of Nephrology, Department of Medicine, University of Texas Health San Antonio, San Antonio, Texas, USA.

Publikováno v: JCI insight [JCI Insight] 2024 Jun 10; Vol. 9 (11). Date of Electronic Publication: 2024 Jun 10.

Rationale and design of the Nephrotic Syndrome Study Network (NEPTUNE) Match in glomerular diseases: designing the right trial for the right patient, today.

Autor: Trachtman H; Division of Nephrology, Department of Pediatrics, University of Michigan, Ann Arbor, Michigan, USA., Desmond H; Division of Nephrology, Department of Pediatrics, University of Michigan, Ann Arbor, Michigan, USA., Williams AL; Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Mariani LH; Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Eddy S; Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Ju W; Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA., Barisoni L; Department of Pathology and Medicine, Duke University, Durham, North Carolina, USA., Ascani HK; Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Uhlmann WR; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA; Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, USA., Spino C; Statistical Analysis, Biomedical and Educational Research Unit, University of Michigan, Ann Arbor, Michigan, USA., Holzman LB; Renal-Electrolyte and Hypertension Division, Department of Internal Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA., Sedor JR; Department of Kidney Medicine, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio, USA; Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA., Gadegbeku C; Department of Kidney Medicine, Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio, USA., Subramanian L; Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Lienczewski CC; Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Manieri T; Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA., Roberts SJ; Department of Health Behavior and Health Education, University of Michigan School of Public Health, Ann Arbor, Michigan, USA., Gipson DS; Division of Nephrology, Department of Pediatrics, University of Michigan, Ann Arbor, Michigan, USA., Kretzler M; Division of Nephrology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA. Electronic address: kretzler@umich.edu.

Publikováno v: Kidney international [Kidney Int] 2024 Feb; Vol. 105 (2), pp. 218-230.

An atlas of healthy and injured cell states and niches in the human kidney.

Autor: Lake BB; Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA.; San Diego Institute of Science, Altos Labs, San Diego, CA, USA., Menon R; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA., Winfree S; Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE, USA., Hu Q; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Melo Ferreira R; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA., Kalhor K; Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA., Barwinska D; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA., Otto EA; Department of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI, USA., Ferkowicz M; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA., Diep D; Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA.; San Diego Institute of Science, Altos Labs, San Diego, CA, USA., Plongthongkum N; Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA., Knoten A; Department of Medicine, Washington University School of Medicine, St Louis, MO, USA., Urata S; Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA., Mariani LH; Department of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI, USA., Naik AS; Department of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI, USA., Eddy S; Department of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI, USA., Zhang B; Department of Medicine, Washington University School of Medicine, St Louis, MO, USA., Wu Y; Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA.; San Diego Institute of Science, Altos Labs, San Diego, CA, USA., Salamon D; Department of Medicine, Washington University School of Medicine, St Louis, MO, USA., Williams JC; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA., Wang X; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Balderrama KS; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Hoover PJ; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Murray E; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Marshall JL; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Noel T; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Vijayan A; Department of Medicine, Washington University School of Medicine, St Louis, MO, USA., Hartman A; New York Genome Center, New York, NY, USA., Chen F; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Waikar SS; Section of Nephrology, Boston University School of Medicine and Boston Medical Center, Boston, MA, USA., Rosas SE; Kidney and Hypertension Unit, Joslin Diabetes Center, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Wilson FP; Department of Medicine, Yale University School of Medicine, New Haven, CT, USA., Palevsky PM; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Kiryluk K; Department of Medicine, Columbia University, New York, NY, USA., Sedor JR; Lerner Research and Glickman Urology and Kidney Institutes, Cleveland Clinic, Cleveland, OH, USA., Toto RD; Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX, USA., Parikh CR; Division of Nephrology, Johns Hopkins School of Medicine, Baltimore, MD, USA., Kim EH; Department of Surgery, Washington University School of Medicine, St Louis, MO, USA., Satija R; New York Genome Center, New York, NY, USA., Greka A; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Macosko EZ; Broad Institute of Harvard and MIT, Cambridge, MA, USA., Kharchenko PV; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.; San Diego Institute of Science, Altos Labs, San Diego, CA, USA., Gaut JP; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA., Hodgin JB; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Eadon MT; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA. meadon@iupui.edu., Dagher PC; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA. pdaghe2@iu.edu., El-Achkar TM; Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA. telachka@iu.edu., Zhang K; Department of Bioengineering, University of California, San Diego, La Jolla, CA, USA. kzhang@bioeng.ucsd.edu.; San Diego Institute of Science, Altos Labs, San Diego, CA, USA. kzhang@bioeng.ucsd.edu., Kretzler M; Department of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, MI, USA. kretzler@med.umich.edu., Jain S; Department of Medicine, Washington University School of Medicine, St Louis, MO, USA. sanjayjain@wustl.edu.; Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO, USA. sanjayjain@wustl.edu.

Publikováno v: Nature [Nature] 2023 Jul; Vol. 619 (7970), pp. 585-594. Date of Electronic Publication: 2023 Jul 19.

Failure to Advance Access to Kidney Transplantation over Two Decades in the United States.

Autor: Schold JD; Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio.; Center for Populations Health Research, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio., Mohan S; Department of Medicine, Division of Nephrology, Columbia University Vagelos College of Physicians & Surgeons, New York, New York.; Department of Epidemiology, Columbia University Mailman School of Public Health, New York, New York., Huml A; Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio., Buccini LD; Center for Populations Health Research, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio., Sedor JR; Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio., Augustine JJ; Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio., Poggio ED; Glickman Urological and Kidney Institute, Cleveland Clinic, Cleveland, Ohio.

Publikováno v: Journal of the American Society of Nephrology : JASN [J Am Soc Nephrol] 2021 Apr; Vol. 32 (4), pp. 913-926. Date of Electronic Publication: 2021 Feb 11.

Kidney Genetics: Continuing Discoveries and a Roadmap to the Clinic.

Autor: Sedor JR; Glickman Urology and Kidney and Lerner Research Institutes, Cleveland Clinic, Cleveland, Ohio.; Departments of Molecular Medicine and Physiology and Biophysics, Case Western Reserve University, Cleveland, Ohio.

Publikováno v: Journal of the American Society of Nephrology : JASN [J Am Soc Nephrol] 2023 Apr 01; Vol. 34 (4), pp. 519-520. Date of Electronic Publication: 2023 Feb 09.