Zobrazeno 1 - 10
of 373
pro vyhledávání: '"Secondary damage"'
Autor:
Daniel J Hellenbrand, Charles M Quinn, Zachariah J Piper, Ryan T Elder, Raveena R Mishra, Taylor L Marti, Phoebe M Omuro, Rylie M Roddick, Jae Sung Lee, William L Murphy, Amgad S Hanna
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 6, Pp 1308-1317 (2024)
[INLINE:1] After spinal cord injury, there is an extensive infiltration of immune cells, which exacerbates the injury and leads to further neural degeneration. Therefore, a major aim of current research involves targeting the immune response as a tre
Externí odkaz:
https://doaj.org/article/026b4788f0ef4aa0aeaf0028d5154190
Publikováno v:
Molecular Brain, Vol 16, Iss 1, Pp 1-16 (2023)
Abstract Necroptosis is known to play an important role in the pathophysiology of cerebral ischemia; however, its role in the occurrence of secondary thalamic injury after focal cerebral infarction and the mechanism about how mixed lineage kinase dom
Externí odkaz:
https://doaj.org/article/3ea1369bfa6d464bac3887c521cdd462
Publikováno v:
Анналы клинической и экспериментальной неврологии, Vol 17, Iss 1, Pp 55-68 (2023)
Head injury is one of the main disability causes among the working-age population. Stroke energy induces mechanical injury of tissues to launch secondary damage, i.e. neurotransmission, blood-brain barrier disruption, blood infiltration of brain tiss
Externí odkaz:
https://doaj.org/article/277d1db5940441e9a6c54fe62e04afaa
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Akademický článek
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Akademický článek
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Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-16 (2020)
Abstract Background Secondary damage after spinal cord injury (SCI) is characterized by a cascade of events including hemorrhage, apoptosis, oxidative stress, and inflammation which increase the lesion size which can influence the functional impairme
Externí odkaz:
https://doaj.org/article/a70ab5f2a1cd420dbbd6f04516acaa5b
Autor:
Anne van der Meij, Marianne A. A. van Walderveen, Nyika D. Kruyt, Erik W. van Zwet, Eric J. Liebler, Michel D. Ferrari, Marieke J. H. Wermer
Publikováno v:
Trials, Vol 21, Iss 1, Pp 1-6 (2020)
Abstract Background Secondary damage due to neurochemical and inflammatory changes in the penumbra in the first days after ischemic stroke contributes substantially to poor clinical outcome. In animal models, vagus nerve stimulation (VNS) inhibits th
Externí odkaz:
https://doaj.org/article/06bbd86e02064a7e9a9e5a3fa0d24d14
Autor:
Lu Ding, Wen-Jin Fu, Hong-Yan Di, Xiao-Min Zhang, Yu-Tian Lei, Kang-Zhen Chen, Tao Wang, Hong-Fu Wu
Publikováno v:
Neural Regeneration Research, Vol 15, Iss 8, Pp 1560-1567 (2020)
Long non-coding RNAs (lncRNAs) are abundantly expressed in the central nervous system and exert a critical role in gene regulation via multiple biological processes. To uncover the functional significance and molecular mechanisms of lncRNAs in spinal
Externí odkaz:
https://doaj.org/article/c1cba97e63cd45cabbce7a5f1664f8c5
Autor:
Elizaveta A. Dutysheva, Elena R. Mikhaylova, Maria A. Trestsova, Alexander I. Andreev, Danila Yu. Apushkin, Irina A. Utepova, Polina O. Serebrennikova, Eugenia A. Akhremenko, Nikolay D. Aksenov, Elizaveta I. Bon’, Sergey M. Zimatkin, Oleg N. Chupakhin, Boris A. Margulis, Irina V. Guzhova, Vladimir F. Lazarev
Publikováno v:
Pharmaceutics, Vol 15, Iss 1, p 7 (2022)
The recovery period after traumatic brain injury (TBI) is often complicated by secondary damage that may last for days or even months after trauma. Two proteins, Hsp70 and glyceraldehyde-3-phosphate dehydrogenase (GAPDH), were recently described as m
Externí odkaz:
https://doaj.org/article/af9f729ef87b4ef4b389249d5ce0fbec