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The effect of pH on the in-vitro dissolution of three second-generation sulphonylurea preparations: mechanism of antacid-sulphonylurea interaction

Autor: Pertti J. Neuvonen, Pasi Lehto, Kari T. K. Ivistö, Kari Laine

Publikováno v: The Journal of pharmacy and pharmacology. 48(9)

Simultaneously administered magnesium hydroxide or sodium bicarbonate can increase the rate and extent of absorption of non-micronized glibenclamide and glipizide. To clarify the mechanism of this interaction we have studied the effect of pH on the d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ed2ae2234e6c9fbc50344c6e10a8498
https://pubmed.ncbi.nlm.nih.gov/8910849

Rise of plasma t‐PA fibrinolytic activity in a group of maturity onset diabetic patients shifted from a first generation (tolbutamide) to a second generation sulphonylurea (gliclazide)

Autor: Jørgen Gram, A. Kold, Jørgen Jespersen

Publikováno v: GRAM, J, KOLD, A & JESPERSEN, J 1989, ' Rise of plasma t-PA fibrinolytic activity in a group of maturity onset diabetic patients shifted from a first generation (tolbutamide) to a second generation sulphonylurea (gliclazide) ', Journal of Internal Medicine, vol. 225, no. 4, pp. 241-247 . https://doi.org/10.1111/j.1365-2796.1989.tb00073.x

During treatment with tolbutamide 10 maturity onset diabetic patients had no detectable activity of tissue‐type plasminogen activator (t‐PA) determined on two occasions 3 months apart. All 10 patients responded on the change in treatment to glicl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b768fc66e8511f3fa5dbef537e3dca
https://portal.findresearcher.sdu.dk/da/publications/7229beba-fb9a-4af5-94a7-f4670ad6cdac

Extrapancreatic action of sulphonylureas: effect of gliquidone on insulin and glucagon binding to rat liver plasma membranes

Autor: M. Haslbeck, Hellmut Mehnert, W. Bachmann, I. Böttger

Publikováno v: European Journal of Clinical Investigation. 9:411-415

Gliquidone (a second generation sulphonylurea) was administered orally to normal rats 1 h before killing. Gliquidone treatment led to a decrease in plasma glucose, an increase in insulin and a diminution in glucagon concentration. Insulin binding to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915c51c550ac6a900682ab4e0a83f671
https://doi.org/10.1111/j.1365-2362.1979.tb00905.x

Hypoglycaemic effect of Eriosema kraussianum N. E. Br. [Fabaceae] rootstock hydro-alcohol extract in rats.

Autor: Ojewole, John, Drewes, Siegfried

Publikováno v: Journal of Natural Medicines; Jul2007, Vol. 61 Issue 3, p244-250, 7p