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Akademický článek

Stochastic Episodes of Latent Cytomegalovirus Transcription Drive CD8 T-Cell "Memory Inflation" and Avoid Immune Evasion.

Autor: Griessl M; Institute for Virology, Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Renzaho A; Institute for Virology, Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Freitag K; Institute for Virology, Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Seckert CK; Institute for Virology, Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Reddehase MJ; Institute for Virology, Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Lemmermann NAW; Institute for Virology, Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany.

Publikováno v: Frontiers in immunology [Front Immunol] 2021 Apr 22; Vol. 12, pp. 668885. Date of Electronic Publication: 2021 Apr 22 (Print Publication: 2021).

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Akademický článek

Insufficient Antigen Presentation Due to Viral Immune Evasion Explains Lethal Cytomegalovirus Organ Disease After Allogeneic Hematopoietic Cell Transplantation.

Autor: Holtappels R; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Schader SI; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Oettel O; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Podlech J; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Seckert CK; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Reddehase MJ; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Lemmermann NAW; Institute for Virology and Research Center for Immunotherapy (FZI) at the University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany.

Publikováno v: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2020 Apr 15; Vol. 10, pp. 157. Date of Electronic Publication: 2020 Apr 15 (Print Publication: 2020).

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Akademický článek

Transcripts expressed in cytomegalovirus latency coding for an antigenic IE/E phase peptide that drives "memory inflation".

Autor: Renzaho A; Institute for Virology, University Medical Center, Johannes Gutenberg-University Mainz and Research Center for Immunotherapy (FZI), Obere Zahlbacher Strasse 67, Hochhaus am Augustusplatz, 55131, Mainz, Germany., Schmiedeke JK; Institute for Virology, University Medical Center, Johannes Gutenberg-University Mainz and Research Center for Immunotherapy (FZI), Obere Zahlbacher Strasse 67, Hochhaus am Augustusplatz, 55131, Mainz, Germany., Griessl M; Institute for Virology, University Medical Center, Johannes Gutenberg-University Mainz and Research Center for Immunotherapy (FZI), Obere Zahlbacher Strasse 67, Hochhaus am Augustusplatz, 55131, Mainz, Germany.; Morgan Sindall Professional Services AG, Basel, Switzerland., Kühnapfel B; Institute for Virology, University Medical Center, Johannes Gutenberg-University Mainz and Research Center for Immunotherapy (FZI), Obere Zahlbacher Strasse 67, Hochhaus am Augustusplatz, 55131, Mainz, Germany., Seckert CK; Institute for Virology, University Medical Center, Johannes Gutenberg-University Mainz and Research Center for Immunotherapy (FZI), Obere Zahlbacher Strasse 67, Hochhaus am Augustusplatz, 55131, Mainz, Germany.; Institute for Medical Microbiology and Hygiene, University Medical Center, Johannes Gutenberg-University Mainz, Obere Zahlbacher Strasse 67, Hochhaus am Augustusplatz, 55131, Mainz, Germany., Lemmermann NAW; Institute for Virology, University Medical Center, Johannes Gutenberg-University Mainz and Research Center for Immunotherapy (FZI), Obere Zahlbacher Strasse 67, Hochhaus am Augustusplatz, 55131, Mainz, Germany. lemmermann@uni-mainz.de.

Publikováno v: Medical microbiology and immunology [Med Microbiol Immunol] 2019 Aug; Vol. 208 (3-4), pp. 439-446. Date of Electronic Publication: 2019 Apr 19.

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Akademický článek

Viral latency drives 'memory inflation': a unifying hypothesis linking two hallmarks of cytomegalovirus infection.

Autor: Seckert CK; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz, Obere Zahlbacher Strasse 67, Hochhaus am Augustusplatz, 55131 Mainz, Germany., Griessl M, Büttner JK, Scheller S, Simon CO, Kropp KA, Renzaho A, Kühnapfel B, Grzimek NK, Reddehase MJ

Publikováno v: Medical microbiology and immunology [Med Microbiol Immunol] 2012 Nov; Vol. 201 (4), pp. 551-66. Date of Electronic Publication: 2012 Sep 19.

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Akademický článek

Antigen-presenting cells of haematopoietic origin prime cytomegalovirus-specific CD8 T-cells but are not sufficient for driving memory inflation during viral latency.

Autor: Seckert CK; Institute for Virology, University Medical Center of the Johannes Gutenberg-University, Obere Zahlbacher Strasse 67, Hochhaus am Augustusplatz, 55131 Mainz, Germany., Schader SI; Institute for Virology, University Medical Center of the Johannes Gutenberg-University, Obere Zahlbacher Strasse 67, Hochhaus am Augustusplatz, 55131 Mainz, Germany., Ebert S; Institute for Virology, University Medical Center of the Johannes Gutenberg-University, Obere Zahlbacher Strasse 67, Hochhaus am Augustusplatz, 55131 Mainz, Germany., Thomas D; Institute for Virology, University Medical Center of the Johannes Gutenberg-University, Obere Zahlbacher Strasse 67, Hochhaus am Augustusplatz, 55131 Mainz, Germany., Freitag K; Institute for Virology, University Medical Center of the Johannes Gutenberg-University, Obere Zahlbacher Strasse 67, Hochhaus am Augustusplatz, 55131 Mainz, Germany., Renzaho A; Institute for Virology, University Medical Center of the Johannes Gutenberg-University, Obere Zahlbacher Strasse 67, Hochhaus am Augustusplatz, 55131 Mainz, Germany., Podlech J; Institute for Virology, University Medical Center of the Johannes Gutenberg-University, Obere Zahlbacher Strasse 67, Hochhaus am Augustusplatz, 55131 Mainz, Germany., Reddehase MJ; Institute for Virology, University Medical Center of the Johannes Gutenberg-University, Obere Zahlbacher Strasse 67, Hochhaus am Augustusplatz, 55131 Mainz, Germany., Holtappels R; Institute for Virology, University Medical Center of the Johannes Gutenberg-University, Obere Zahlbacher Strasse 67, Hochhaus am Augustusplatz, 55131 Mainz, Germany.

Publikováno v: The Journal of general virology [J Gen Virol] 2011 Sep; Vol. 92 (Pt 9), pp. 1994-2005. Date of Electronic Publication: 2011 Jun 01.

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Akademický článek

Single cell detection of latent cytomegalovirus reactivation in host tissue.

Autor: Marquardt A; Institute of Virology, Hannover Medical School, Hannover, Germany., Halle S; Institute of Immunology, Hannover Medical School, Hannover, Germany., Seckert CK; Institute for Virology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany., Lemmermann NAW; Institute for Virology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany., Veres TZ; Department of Immunology, Allergology and Immunotoxicology, Fraunhofer Institute of Toxicology and Experimental Medicine, Hannover, Germany., Braun A; Department of Immunology, Allergology and Immunotoxicology, Fraunhofer Institute of Toxicology and Experimental Medicine, Hannover, Germany., Maus UA; Department of Experimental Pneumology, Hannover Medical School, Hannover, Germany., Förster R; Institute of Immunology, Hannover Medical School, Hannover, Germany., Reddehase MJ; Institute for Virology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany., Messerle M; Institute of Virology, Hannover Medical School, Hannover, Germany., Busche A; Institute of Virology, Hannover Medical School, Hannover, Germany.

Publikováno v: The Journal of general virology [J Gen Virol] 2011 Jun; Vol. 92 (Pt 6), pp. 1279-1291. Date of Electronic Publication: 2011 Feb 16.

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Akademický článek

Reverse genetics modification of cytomegalovirus antigenicity and immunogenicity by CD8 T-cell epitope deletion and insertion.

Autor: Lemmermann NA; Institute for Virology, University Medical Center of the Johannes Gutenberg-University Mainz, Hochhaus am Augustusplatz, 55101 Mainz, Germany. lemmermann@uni-mainz.de, Kropp KA, Seckert CK, Grzimek NK, Reddehase MJ

Publikováno v: Journal of biomedicine & biotechnology [J Biomed Biotechnol] 2011; Vol. 2011, pp. 812742. Date of Electronic Publication: 2010 Dec 26.

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Akademický článek

A novel transmembrane domain mediating retention of a highly motile herpesvirus glycoprotein in the endoplasmic reticulum.

Autor: Däubner T; Institute for Virology, University Medical Center of the Johannes Gutenberg-University, Mainz, Germany., Fink A, Seitz A, Tenzer S, Müller J, Strand D, Seckert CK, Janssen C, Renzaho A, Grzimek NK, Simon CO, Ebert S, Reddehase MJ, Oehrlein-Karpi SA, Lemmermann NA

Publikováno v: The Journal of general virology [J Gen Virol] 2010 Jun; Vol. 91 (Pt 6), pp. 1524-34. Date of Electronic Publication: 2010 Feb 10.

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