RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells

Autor: Fuhui Chen, Sevim B. Gurler, David Novo, Cigdem Selli, Denis G. Alferez, Secil Eroglu, Kyriaki Pavlou, Jingwei Zhang, Andrew H. Sims, Neil E. Humphreys, Antony Adamson, Andrew Campbell, Owen J. Sansom, Cathy Tournier, Robert B. Clarke, Keith Brennan, Charles H. Streuli, Ahmet Ucar

Publikováno v: Chen, F, Gurler, S B, Novo, D, Selli, C, Alferez, D G, Eroglu, S, Pavlou, K, Zhang, J, Sims, A H, Humphreys, N E, Adamson, A, Campbell, A, Sansom, O J, Tournier, C, Clarke, R B, Brennan, K, Streuli, C H & Ucar, A 2023, ' RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells ', Oncogene, vol. 42, pp. 679-692 . https://doi.org/10.1038/s41388-022-02574-6

Breast cancer stem cells (BCSC) are presumed to be responsible for treatment resistance, tumor recurrence and metastasis of breast tumors. However, development of BCSC-targeting therapies has been held back by their heterogeneity and the lack of BCSC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb1327f89053608b065c8bcfc5ed3d5f
https://doi.org/10.1038/s41388-022-02574-6

Molecular Genetic Testing and Liquid Biopsy in Lung Cancer: Present and Future

Autor: Secil Eroglu, Sibel Oguzkan Balci

Publikováno v: European Journal of Therapeutics. :14-18

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c09991104a2099f74cc102986f4fb3ad
https://doi.org/10.5152/eurjther.2018.1004

Identification of the Variations in the CPT1B and CHKB Genes Along with the HLA-DQB1*06:02 Allele in Turkish Narcolepsy Patients and Healthy Persons

Autor: Ahmet Evlice, Hikmet Yilmaz, Sultan Cingoz, Derya Karadeniz, Oguz Altungoz, Sinem Agilkaya, İbrahim Öztura, Barış Baklan, Secil Eroglu

Publikováno v: Genetic Testing and Molecular Biomarkers. 18:261-268

Background: The HLA-DQB1*06:02 allele across all ethnic groups and the rs5770917 variation between CPT1B and CHKB genes in Japanese and Koreans are common genetic susceptibility factors for narcolepsy. This comprehensive genetic study sought to asses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6154c466472aab74f300e2c3e9ecb4ed
https://doi.org/10.1089/gtmb.2013.0391