Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sec Julie Hoong"'
Autor:
Adam P. Curnock, Giovanna Bossi, Jyothi Kumaran, Lindsay J. Bawden, Rita Figueiredo, Rajeevkumar Tawar, Katherine Wiseman, Emma Henderson, Sec Julie Hoong, Veronica Gonzalez, Hemza Ghadbane, David E.O. Knight, Ronan O’Dwyer, David X. Overton, Christina M. Lucato, Nicola M.G. Smith, Carlos R. Reis, Keith Page, Lorraine M. Whaley, Michelle L. McCully, Stephen Hearty, Tara M. Mahon, Peter Weber
Publikováno v:
JCI Insight, Vol 6, Iss 20 (2021)
The PD-1/PD-L1 pathway is a key immune checkpoint that regulates T cell activation. There is strong rationale to develop PD-1 agonists as therapeutics against autoimmunity, but progress in this area has been limited. Here, we generated T cell recepto
Externí odkaz:
https://doaj.org/article/76d2b586086f49e3988424380f1b73ad
Autor:
Cristiano Scottà, Giorgia Fanelli, Sec Julie Hoong, Marco Romano, Estefania Nova Lamperti, Mitalee Sukthankar, Giuliana Guggino, Henrieta Fazekasova, Kulachelvy Ratnasothy, Pablo D. Becker, Behdad Afzali, Robert I. Lechler, Giovanna Lombardi
Publikováno v:
Haematologica, Vol 101, Iss 1 (2016)
Immunosuppressive drugs in clinical transplantation are necessary to inhibit the immune response to donor antigens. Although they are effective in controlling acute rejection, they do not prevent long-term transplant loss from chronic rejection. In a
Externí odkaz:
https://doaj.org/article/e6b90880f686439bb880eefbc18e9690
Autor:
Leena Halim, Marco Romano, Reuben McGregor, Isabel Correa, Polychronis Pavlidis, Nathali Grageda, Sec-Julie Hoong, Muhammed Yuksel, Wayel Jassem, Rosalind F. Hannen, Mark Ong, Olivia Mckinney, Bu’Hussain Hayee, Sophia N. Karagiannis, Nicholas Powell, Robert I. Lechler, Estefania Nova-Lamperti, Giovanna Lombardi
Publikováno v:
Cell Reports, Vol 20, Iss 3, Pp 757-770 (2017)
Regulatory T cells (Tregs) play a pivotal role in maintaining immunological tolerance, but they can also play a detrimental role by preventing antitumor responses. Here, we characterized T helper (Th)-like Treg subsets to further delineate their biol
Externí odkaz:
https://doaj.org/article/ac5022db56944e29b0db055e9ca4656e
Autor:
Polychronis Pavlidis, Giovanna Lombardi, Leena Halim, Sophia N. Karagiannis, Isabel Correa, Rosalind F. Hannen, Reuben McGregor, Nick Powell, Nathali Grageda, Wayel Jassem, Robert I. Lechler, Mark Ong, Muhammed Yuksel, Bu'Hussain Hayee, Estefania Nova-Lamperti, Marco Romano, Olivia Mckinney, Sec-Julie Hoong
Publikováno v:
Halim, L, Romano, M, McGregor, R, Correa, I, Pavlidis, P, Grageda, N, Hoong, S-J, Yuksel, M, Jassem, W, Hannen, R F, Ong, M, Mckinney, O, Hayee, BH, Karagiannis, S N, Powell, N, Lechler, R I, Nova-Lamperti, E & Lombardi, G 2017, ' An Atlas of Human Regulatory T Helper-like Cells Reveals Features of Th2-like Tregs that Support a Tumorigenic Environment ', Cell Reports, vol. 20, no. 3, pp. 757-770 . https://doi.org/10.1016/j.celrep.2017.06.079
Cell Reports
Cell Reports, Vol 20, Iss 3, Pp 757-770 (2017)
Cell Reports
Cell Reports, Vol 20, Iss 3, Pp 757-770 (2017)
Summary Regulatory T cells (Tregs) play a pivotal role in maintaining immunological tolerance, but they can also play a detrimental role by preventing antitumor responses. Here, we characterized T helper (Th)-like Treg subsets to further delineate th