Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Sebyung Kang"'
Autor:
Hyukjun Choi, Mirae Yeo, Yujin Kang, Hyo Jeong Kim, Seong Guk Park, Eunjung Jang, Sung Ho Park, Eunhee Kim, Sebyung Kang
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract The aggressive proliferation of tumor cells often requires increased glucose uptake and excessive anaerobic glycolysis, leading to the massive production and secretion of lactate to form a unique tumor microenvironment (TME). Therefore, regu
Externí odkaz:
https://doaj.org/article/317aac2a24564665b269c15a0546bc20
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-17 (2022)
Abstract The plant toxin ricin, especially its cytotoxic A chain (RTA), can be genetically engineered with targeting ligands to develop specific anti-cancer recombinant immunotoxins (RITs). Here, we used affibody molecules targeting two cancer biomar
Externí odkaz:
https://doaj.org/article/f53861c53fa24c0f9f7c54446d999f2c
Autor:
Ki-Beom Moon, Jae-Heung Jeon, Hyukjun Choi, Ji-Sun Park, Su-Jin Park, Hyo-Jun Lee, Jeong Mee Park, Hye Sun Cho, Jae Sun Moon, Hyunwoo Oh, Sebyung Kang, Hugh S. Mason, Suk-Yoon Kwon, Hyun-Soon Kim
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-7 (2022)
Abstract The pandemic of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has caused a public health emergency, and research on the development of various types of vaccines is rapidly progressing at an unprecedented development speed inte
Externí odkaz:
https://doaj.org/article/0603aea4c9b647d68a4daa4c22cc18fc
Autor:
Jun Yong Oh, Han Sol Kim, L. Palanikumar, Eun Min Go, Batakrishna Jana, Soo Ah Park, Ho Young Kim, Kibeom Kim, Jeong Kon Seo, Sang Kyu Kwak, Chaekyu Kim, Sebyung Kang, Ja-Hyoung Ryu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
The efficacy of nanoparticles can be significantly inhibited by serum proteins binding to them. Here, the author developed a supramolecularly constructed protein corona on nanoparticles, which minimises interactions with serum proteins to prevent the
Externí odkaz:
https://doaj.org/article/990779936dde4d118e6b9a14546a8eef
Publikováno v:
Sensors, Vol 15, Iss 5, Pp 10481-10510 (2015)
Surface plasmon resonance (SPR) is a label-free detection method which has emerged during the last two decades as a suitable and reliable platform in clinical analysis for biomolecular interactions. The technique makes it possible to measure interact
Externí odkaz:
https://doaj.org/article/ab630fd6e315483499878b3801ccc69e
Publikováno v:
Biomacromolecules. 23:5193-5201
With the continued advancement in the design and engineering of hydrogels for biomedical applications, there is a growing interest in imparting stimuli-responsiveness to the hydrogels in order to control their physicomechanical properties in a more p
TRAIL & EGFR affibody dual-display on a protein nanoparticle synergistically suppresses tumor growth
Autor:
Heejin Jun, Eunjung Jang, Hansol Kim, Mirae Yeo, Seong Guk Park, Jaehyeok Lee, Kyeong Jin Shin, Young Chan Chae, Sebyung Kang, Eunhee Kim
Publikováno v:
Journal of Controlled Release. 349:367-378
The TNF-related apoptosis-inducing ligand (TRAIL) is a promising anticancer drug candidate because it selectively binds to the proapoptotic death receptors, which are frequently overexpressed in a wide range of cancer cells, subsequently inducing str
Publikováno v:
BMB Reports. 55:175-180
Autor:
Hansol Kim, Seokha Jin, HyungJoon Cho, MungSoo Kang, Hyukjun Choi, Heejin Jun, Seong Guk Park, Sebyung Kang
Publikováno v:
Journal of Controlled Release. 335:269-280
Magnetic resonance imaging (MRI) is a non-invasive in vivo imaging tool, providing high enough spatial resolution to obtain both the anatomical and the physiological information of patients. However, MRI generally suffers from relatively low sensitiv
Autor:
Chang Kyu Lee, Sebyung Kang
Publikováno v:
Biomacromolecules. 22:2649-2658
The successful development of targeted nanoparticle (NP)-based therapeutics depends on the effective conjugation of targeting ligands to the NP. However, conventional methods based on chemical reactive groups such as N-hydroxysuccinimide, 1-ethyl-3-(