Zobrazeno 1 - 10
of 727
pro vyhledávání: '"Seber P"'
Autor:
Seber, Pedro
Glycosylation, a protein modification, has multiple essential functional and structural roles. O-GlcNAcylation, a subtype of glycosylation, has the potential to be an important target for therapeutics, but methods to reliably predict O-GlcNAcylation
Externí odkaz:
http://arxiv.org/abs/2402.17131
Autor:
Seber, Pedro, Braatz, Richard D.
Interpretable architectures can have advantages over black-box architectures, and interpretability is essential for the application of machine learning in critical settings, such as aviation or medicine. However, the simplest, most commonly used inte
Externí odkaz:
http://arxiv.org/abs/2402.17120
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 46, Iss , Pp S38-S39 (2024)
Objetivos: Dor crônica é uma complicação frequente e debilitante das Doenças Falciformes (DF). O objetivo deste estudo foi avaliar seu impacto na saúde mental e qualidade de vida dos pacientes, além de buscar identificar moléculas associadas
Externí odkaz:
https://doaj.org/article/6cc8b9086c884594b9cb99ed21f317de
Autor:
BP Nasr, SRC Toledo, IO Dias, F Tesser-Gamba, MGC Pires, JT Gouveia, E Debuono, NS Santos, LL Quintino, MGA Matos, A Seber, AVL Souza
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 46, Iss , Pp S384-S385 (2024)
B-ALL is heterogeneous disease and its classification can be defined by recurrent genetic abnormalities as WHO 5th. Recent gene expression studies have identified genetic drivers that confer distinct prognostic impact, as B-ALL ZNF384-r. We report a
Externí odkaz:
https://doaj.org/article/dff6fc5d60234084b92431a1dd84ce38
Autor:
CNM Breviglieri, RG Vasconcelos, CN Santos, VC Ginani, MRS Oliveira, ABW Batalha, JF Marques, GS Alencar, A Seber
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 46, Iss , Pp S688- (2024)
Pediatric Acute Myeloid Leukemia (AML) presents significant treatment challenges, particularly post-transplant relapses. The use of the only specific immunotherapy for AML may increase transplant-related toxicities due to the calicheamicin. This scar
Externí odkaz:
https://doaj.org/article/e55c74ee82c8490bb7e7420f999c4f65
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 46, Iss , Pp S686- (2024)
Chimeric antigen receptor (CAR) T-cell therapy is a choice for ALL relapsed post-HCT but is hindered by cost and the required lengthy washout period, emphasizing the need for new strategies to prevent relapse. For those at high relapse risk due to di
Externí odkaz:
https://doaj.org/article/74d8ff45a74541df89beedfbca6a21b1
Autor:
CNM Breviglieri, CN Santos, RG Vasconcelos, VC Ginani, ABW Batalha, MRS Oliveira, GS Alencar, JF Marques, A Seber
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 46, Iss , Pp S688-S689 (2024)
Relapsed Acute Lymphoblastic Leukemia (ALL) post-hematopoietic stem cell transplantation (HCT) have very poor outcomes. Patients face increased toxicity and poorer responses to therapy. With limited access to Chimeric Antigen Receptor (CAR) T-cell th
Externí odkaz:
https://doaj.org/article/dde0e2390c9542799a4ba743309d9af4
Autor:
KBB Pagnano, IA Siqueira, G Campos, NCR Guerrero, JF Camargo, GO Duarte, G Duffles, VH Guidini, B Sabioni, FS Seguro, N Hamerschlak, M Rodrigues, EG Souza, PSR Cardoso, GH Magalhães, ATS Quixada, A Seber, IHB Massaut, LM Fogliatto, NN Gonçalves, RS Vasconcelos, S Vidor, C Souza, V Funke
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 46, Iss , Pp S507-S508 (2024)
Objetivos: Analisar os desfechos clínicos de pacientes com leucemia mieloide crônica (LMC) tratados com asciminibe. Métodos: Coletamos dados demográficos, histórico médico, tratamentos anteriores, resposta e eventos adversos de pacientes com LM
Externí odkaz:
https://doaj.org/article/1072e66e61404f049e5bdb46e971cda0
Autor:
ACL Alves, MRA Gomes, AS Ramos, CM Lustosa, G Zamperlini, LL Quintino, VC Ginani, RV Gouveia, A Seber, OMWO Félix
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 46, Iss , Pp S991- (2024)
A major challenge for transplant centers is the graft acquisition when a compatible unrelated donor is chosen for the procedure. In addition to the complex logistics that involve several critical steps and the need of an experienced multidisciplinary
Externí odkaz:
https://doaj.org/article/1d0ca67dcc8c46aebbd845e7ea3f649f
Autor:
MRA Gomes, AS Ramos, ACL Alves, G Zamperlini, PGG Granja, DVB Cruz, CMV Alferi, V Quintiliano, A Seber, OMWO Félix
Publikováno v:
Hematology, Transfusion and Cell Therapy, Vol 46, Iss , Pp S991-S992 (2024)
During the process of cryopreservation of hematopoietic stem cells (CTH), the Dimelthyl Sulfoxide (DMSO) is responsible for ensuring a better cell viability and a satisfactory engraftment but, at the time of the graft infusion, it can cause serious a
Externí odkaz:
https://doaj.org/article/b88b4f2a386649fabef41698025b2316