Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sebastien Pomel"'
Publikováno v:
PLoS Pathogens, Vol 4, Iss 10, p e1000188 (2008)
Apicomplexan parasites are dependent on an F-actin and myosin-based motility system for their invasion into and escape from animal host cells, as well as for their general motility. In Toxoplasma gondii and Plasmodium species, the actin filaments and
Externí odkaz:
https://doaj.org/article/5598104c133f4a279dfa517fe8414d59
Autor:
Sameh Obeid, Eloisa Berbel-Manaia, Valérie Nicolas, Indira Dennemont, Julien Barbier, Jean-Christophe Cintrat, Daniel Gillet, Philippe M. Loiseau, Sébastien Pomel
Publikováno v:
iScience, Vol 26, Iss 11, Pp 108144- (2023)
Summary: Antileishmanial chemotherapy is currently limited due to severe toxic side effects and drug resistance. Hence, new antileishmanial compounds based on alternative approaches, mainly to avoid the emergence of drug resistance, are needed. The p
Externí odkaz:
https://doaj.org/article/dbcda9f2fa5048c280c47e5708a19e5b
Autor:
Zineb Fechtali-Moute, Sébastien Pomel
Publikováno v:
Microorganisms, Vol 12, Iss 3, p 474 (2024)
Free-living amoebae (FLA) are widely distributed protozoa in both natural and artificial environments such as drinking water. In addition to the ability of all FLA to transport various pathogenic microorganisms, certain species, such as Acanthamoeba
Externí odkaz:
https://doaj.org/article/b3d0586976d643dfa228f37c54c9f207
Autor:
Pedro G. Vásquez-Ocmín, Sandrine Cojean, Vincent Roumy, Guillaume Marti, Sébastien Pomel, Alice Gadea, Karine Leblanc, Indira Dennemont, Liliana Ruiz-Vásquez, Hivelli Ricopa Cotrina, Wilfredo Ruiz Mesia, Stéphane Bertani, Lastenia Ruiz Mesia, Alexandre Maciuk
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
High prevalence of parasitic or bacterial infectious diseases in some world areas is due to multiple reasons, including a lack of an appropriate health policy, challenging logistics and poverty. The support to research and development of new medicine
Externí odkaz:
https://doaj.org/article/df600cdb6d794250a06871315c0784ac
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Acanthamoeba castellanii is a widespread Free-Living Amoeba (FLA) that can cause severe ocular or cerebral infections in immunocompetent and immunocompromised patients, respectively, besides its capacity to transport diverse pathogens. During their l
Externí odkaz:
https://doaj.org/article/b8772e9695624c798671da5229fce8ba
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 3, Pp 791-805 (2021)
Abstract Free‐living amoebae (FLAs) are protozoa developing autonomously in diverse natural or artificial environments. The FLAs Acanthamoeba spp., Balamuthia mandrillaris, and Naegleria fowleri represent a risk for human health as they can become
Externí odkaz:
https://doaj.org/article/7c0285854ae94d998bea7bcf935e2b8f
Publikováno v:
PLoS Pathogens, Vol 4, Iss 10, p e1000188 (2008)
PLoS Pathogens
PLoS Pathogens
Apicomplexan parasites are dependent on an F-actin and myosin-based motility system for their invasion into and escape from animal host cells, as well as for their general motility. In Toxoplasma gondii and Plasmodium species, the actin filaments and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e50f8b9ffc784e09700093d9d7aa466f
http://europepmc.org/articles/PMC2563030?pdf=render
http://europepmc.org/articles/PMC2563030?pdf=render
Autor:
Gwenaëlle Jézéquel, Laura Nogueira de Faria Cardoso, Florent Olivon, Indira Dennemont, Cécile Apel, Marc Litaudon, Fanny Roussi, Sébastien Pomel, Sandy Desrat
Publikováno v:
Molecules, Vol 27, Iss 22, p 7892 (2022)
Quinoline derivatives and especially quinolones are considered as privileged structures in medicinal chemistry and are often associated with various biological properties. We recently isolated a series of original monoterpenyl quinolones from the bar
Externí odkaz:
https://doaj.org/article/9740a22337734f6582856a044efcb85f
Autor:
Juliane S. Lanza, Virginia M. R. Vallejos, Guilherme S. Ramos, Ana Carolina B. de Oliveira, Cynthia Demicheli, Luis Rivas, Sébastien Pomel, Philippe M. Loiseau, Frédéric Frézard
Publikováno v:
Pharmaceutics, Vol 14, Iss 8, p 1743 (2022)
This work aims to evaluate whether nanoassemblies (NanoSb) made from antimony(V) complexes with octanoyl-N-methylglucamide (SbL8) or decanoyl-N-methylglucamide (SbL10) would effectively target the infection sites in visceral and cutaneous leishmanias
Externí odkaz:
https://doaj.org/article/8e62a4658a024c4a921dceb6b4c0fade
Autor:
Philippe M. Loiseau, Kaluvu Balaraman, Gillian Barratt, Sébastien Pomel, Rémy Durand, Frédéric Frézard, Bruno Figadère
Publikováno v:
Molecules, Vol 27, Iss 7, p 2313 (2022)
There is a need for new, cost-effective drugs to treat leishmaniasis. A strategy based on traditional medicine practiced in Bolivia led to the discovery of the 2-substituted quinoline series as a source of molecules with antileishmanial activity and
Externí odkaz:
https://doaj.org/article/829cfda8e3c8483e98177b208718e918