Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sebastien Pfeffer"'
Autor:
Eleonore Ostermann, Lee Tuddenham, Cecile Macquin, Ghada Alsaleh, Julie Schreiber-Becker, Melanie Tanguy, Seiamak Bahram, Sebastien Pfeffer, Philippe Georgel
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43744 (2012)
Regulation of gene expression by microRNAs (miRNAs) is now considered as an essential mechanism for cell development and homeostasis. Indeed, numerous studies have reported that modulating their expression, maturation, or activity can affect cell sur
Externí odkaz:
https://doaj.org/article/54280482a03249e3908c3ed8db9706e8
Autor:
Noha Semaan, Laurent Frenzel, Ghada Alsaleh, Guillaume Suffert, Jacques-Eric Gottenberg, Jean Sibilia, Sebastien Pfeffer, Dominique Wachsmann
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e19827 (2011)
TNF-α is a major cytokine implicated in rheumatoid arthritis. Its expression is regulated both at the transcriptional and posttranscriptional levels and recent data demonstrated that miRNAs are implicated in TNF-α response in macrophages. LPS-activ
Externí odkaz:
https://doaj.org/article/783400689f68411591c8db424fa80bd8
Autor:
Mélanie Messmer, Louison Pierson, Charline Pasquier, Nikola Djordjevic, Johana Chicher, Philippe Hammann, Sébastien Pfeffer, Erika Girardi
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-17 (2024)
Abstract Background RNA helicases are emerging as key factors regulating host-virus interactions. The DEAD-box ATP-dependent RNA helicase DDX5, which plays an important role in many aspects of cellular RNA biology, was also found to either promote or
Externí odkaz:
https://doaj.org/article/f30e94f5d5ec4701b25198871077b914
Publikováno v:
Seminars in Cell & Developmental Biology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::f57667d26b93b92a09289bcd3468380d
Autor:
Seungjae Lee, David Jee, Sid Srivastava, Acong Yang, Abhinav Ramidi, Renfu Shang, Diane Bortolamiol-Becet, Sébastien Pfeffer, Shuo Gu, Jiayu Wen, Eric C. Lai
Publikováno v:
Cell Reports, Vol 42, Iss 2, Pp 112111- (2023)
Summary: Canonical microRNA (miRNA) hairpins are processed by the RNase III enzymes Drosha and Dicer into ∼22 nt RNAs loaded into an Argonaute (Ago) effector. In addition, splicing generates numerous intronic hairpins that bypass Drosha (mirtrons)
Externí odkaz:
https://doaj.org/article/e5a6e87b637141948837c14c388a3164
Autor:
Morgane Baldaccini, Sébastien Pfeffer
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12 (2021)
One of the first layers of protection that metazoans put in place to defend themselves against viruses rely on the use of proteins containing DExD/H-box helicase domains. These members of the duplex RNA–activated ATPase (DRA) family act as sensors
Externí odkaz:
https://doaj.org/article/9baa858d19794e0a8d82ec04154c0ac5
Autor:
dominique Wachsmann, Ghada Alsaleh, Noha Semaan, Guillaume Suffert, Sebastien Pfeffer, Laurent Frenzel, Jacques-Eric Gottenberg, Jean Sibilia
Publikováno v:
The Journal of Immunology. 182:99.52-99.52
We reported previously that LPS-activated synoviocytes fibroblast-like (FLS) isolated from rheumatoid arthritis (RA) patients express IL-18 mRNA but they do not release IL-18. As this inhibition was due to a rapid degradation of IL-18 mRNA, our group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa8dea80e85cffbb455a4d742df8a56c
https://doi.org/10.4049/jimmunol.182.supp.99.52
https://doi.org/10.4049/jimmunol.182.supp.99.52
Autor:
Thomas C Montavon, Morgane Baldaccini, Mathieu Lefèvre, Erika Girardi, Béatrice Chane-Woon-Ming, Mélanie Messmer, Philippe Hammann, Johana Chicher, Sébastien Pfeffer
Publikováno v:
PLoS Pathogens, Vol 17, Iss 5, p e1009549 (2021)
The antiviral innate immune response mainly involves type I interferon (IFN) in mammalian cells. The contribution of the RNA silencing machinery remains to be established, but several recent studies indicate that the ribonuclease DICER can generate v
Externí odkaz:
https://doaj.org/article/40b382e1a8574c88a204a648527086ec
Autor:
Olivier Petitjean, Erika Girardi, Richard Patryk Ngondo, Vladimir Lupashin, Sébastien Pfeffer
Publikováno v:
mSphere, Vol 5, Iss 6 (2020)
ABSTRACT Double-stranded RNA (dsRNA) is the hallmark of many viral infections. dsRNA is produced either by RNA viruses during replication or by DNA viruses upon convergent transcription. Synthetic dsRNA is also able to mimic viral-induced activation
Externí odkaz:
https://doaj.org/article/ce2e1b6b2c6d4e95b2cdb7888fed112e
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Every living organism has to constantly face threats from the environment and deal with a large number of pathogens against which it has to defend itself to survive. Among those, viruses represent a large class of obligatory intracellular parasites,
Externí odkaz:
https://doaj.org/article/f9dde1f099844a0284a371f774efb8f5