Versatile UCST-based thermoresponsive hydrogels for loco-regional sustained drug delivery

Autor: Michel Vert, Sebastien Lenglet, Pierre-Emmanuel Colombo, Mahfoud Boustta, Sylvain Poujol

Publikováno v: Journal of Controlled Release
Journal of Controlled Release, Elsevier, 2014, 174, pp.1--6. ⟨10.1016/j.jconrel.2013.10.040⟩

IMPACT: 7.877; International audience; Poly(N-acryloyl glycinamide) is a neutral polymer that can form gel-sol thermoresponsive systems with upper critical solution temperature in aqueous media. The temperature of the reversible gel-sol transition de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d38d4ab82b2d0c1fc3c795cdc28ebc6
https://doi.org/10.1016/j.jconrel.2013.10.040

Activation of 5-HT7 Receptor in Rat Glomerulosa Cells Is Associated with an Increase in Adenylyl Cyclase Activity and Calcium Influx through T-Type Calcium Channels

Autor: Vincent Contesse, Hubert Vaudry, Estelle Louiset, Catherine Delarue, Sebastien Lenglet

Publikováno v: Endocrinology. 143:1748-1760

Serotonin (5-HT) stimulates aldosterone secretion from the rat adrenal gland through 5-HT(7) receptors. The aim of the present study was to investigate the transduction mechanisms associated with activation of 5-HT(7) receptors in rat glomerulosa cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77301eb128646c2dc67cdc176ebc3159
https://doi.org/10.1210/endo.143.5.8817

Association of Trace Element Levels with Outcomes in Critically Ill COVID-19 Patients

Autor: Hannah Wozniak, Christophe Le Terrier, Steve Primmaz, Noémie Suh, Sébastien Lenglet, Aurélien Thomas, Nicolas Vuilleumier, Sabrina Pagano, Aude de Watteville, Silvia Stringhini, Idris Guessous, Hervé Quintard, Claudia Paula Heidegger, Jérôme Pugin

Publikováno v: Nutrients, Vol 15, Iss 15, p 3308 (2023)

The primary objective of this study was to compare the plasma levels of copper, selenium, and zinc between critically ill COVID-19 patients and less severe COVID-19 patients. The secondary objective was to investigate the association of these trace e

Externí odkaz: https://doaj.org/article/93204f4e8e2b4bc6aa8cd01872febc10

Pharmacological and Molecular Characterization of 5-Hydroxytryptamine 7 Receptors in the Rat Adrenal Gland

Autor: Sebastien Lenglet, Isabelle Lihrmann, Luca Grumolato, V. Contesse, Youssef Anouar, Hubert Vaudry, Catherine Delarue, Hervé Lefebvre

Publikováno v: Molecular Pharmacology
Molecular Pharmacology, American Society for Pharmacology and Experimental Therapeutics, 1999, 56 (3), pp.552-561. ⟨10.1124/mol.56.3.552⟩
Publons
Molecular Pharmacology, 1999, 56 (3), pp.552-561. ⟨10.1124/mol.56.3.552⟩

International audience; Serotonin (5-hydroxytryptamine; 5-HT) is a potent stimulator of aldosterone secretion in the rat adrenal gland but the type of receptor involved in the mechanism of action of 5-HT remains unknown. The aim of the present study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb849aa561ace43807063a62c933186
https://hal-normandie-univ.archives-ouvertes.fr/hal-02427287

Intraplaque Expression of C-Reactive Protein Predicts Cardiovascular Events in Patients with Severe Atherosclerotic Carotid Artery Stenosis

Autor: Aldo Bonaventura, François Mach, Aline Roth, Sébastien Lenglet, Fabienne Burger, Karim J. Brandt, Aldo Pende, Maria Bertolotto, Giovanni Spinella, Bianca Pane, Domenico Palombo, Franco Dallegri, Michele Cea, Nicolas Vuilleumier, Fabrizio Montecucco, Federico Carbone

Publikováno v: Mediators of Inflammation, Vol 2016 (2016)

Serum c-reactive protein (CRP) was suggested for the assessment of intermediate cardiovascular (CV) risk. Here, systemic or intraplaque CRP levels were investigated as predictors of major adverse cardiovascular events (MACEs) in patients with severe

Externí odkaz: https://doaj.org/article/cd88fb269c634f598c88f56b644bc408