Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sebastien Laurent"'
Autor:
Dominique Lambin, Katja Conrath, Tom De Munck, Ann De Blieck, Hans Kelgtermans, Steven Emiel Van Der Plas, Marlon D. Cowart, Christel Jeanne Marie Menet, Sebastien Dropsit, Caroline Joannesse, Oscar Mammoliti, Sebastien Laurent Xavier Martina, Maarten Gees, Giovanni Tricarico, Martin James Inglis Andrews, Anne-Sophie Wesse
Publikováno v:
Journal of Medicinal Chemistry. 64:343-353
Cystic fibrosis (CF) is a life-threatening recessive genetic disease caused by mutations in the gene encoding for the cystic fibrosis transmembrane conductance regulator (CFTR). With the discovery of Ivacaftor and Lumacaftor, it has been shown that a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95c3164798d3ba2edd8da65585ae94bc
https://doi.org/10.1021/acs.jmedchem.0c01796
https://doi.org/10.1021/acs.jmedchem.0c01796
Autor:
Ronnie Chamanza, Niraj Tripathi, Bindu Bennet, Marie-France Perron Lepage, Jayanthi J. Wolf, Karissa Adkins, Keith Nelson, Sean P. Troth, Sebastien Laurent, Rani S. Sellers
Publikováno v:
Toxicologic Pathology. 48:257-276
The design and execution of toxicology studies supporting vaccine development have some unique considerations relative to those supporting traditional small molecules and biologics. A working group of the Society of Toxicologic Pathology Scientific a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f370501659f4588114afd54c2a8cafc
https://doi.org/10.1177/0192623319875085
https://doi.org/10.1177/0192623319875085
Autor:
Sebastien Dropsit, Pieter F. W. Stouten, Linda Tomaskovic, Thierry Christophe, Ellen van der Aar, Maarten Gees, Luc Nelles, Mia Jans, Monica Borgonovi, Evelyne M. Quinton, Katja Conrath, Jan Van Der Schueren, Caroline Joannesse, Hans Kelgtermans, Martin James Inglis Andrews, Sebastien Laurent Xavier Martina, Oscar Mammoliti, Ann De Blieck, Steven Emiel Van Der Plas, Tom De Munck
Publikováno v:
Journal of Medicinal Chemistry. 61:1425-1435
Cystic fibrosis (CF) is caused by mutations in the gene for the cystic fibrosis transmembrane conductance regulator (CFTR). With the discovery of Ivacaftor and Orkambi, it has been shown that CFTR function can be partially restored by administering o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc1598dc3e22fb401aa0908c21814b75
https://doi.org/10.1021/acs.jmedchem.7b01288
https://doi.org/10.1021/acs.jmedchem.7b01288
Autor:
Steven Emiel Van Der Plas, Ann De Blieck, Dominique Lambin, Giovanni Tricarico, Martin James Inglis Andrews, Anne-Sophie Wesse, Marlon D. Cowart, Katja Conrath, Tom De Munck, Maarten Gees, Christel Jeanne Marie Menet, Hans Kelgtermans, Oscar Mammoliti, Caroline Joannesse, Sebastien Laurent Xavier Martina, Sebastien Dropsit
Publikováno v:
Journal of Medicinal Chemistry. 64:13933-13933
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef530fe540a7f240ca9942862582716b
https://doi.org/10.1021/acs.jmedchem.1c01537
https://doi.org/10.1021/acs.jmedchem.1c01537
Cooperation between two modes for DNA replication initiation in the archaeon Thermococcus barophilus
Autor:
Logan Mc Teer, Yann Moalic, Valérie Cueff-Gauchard, Ryan Catchpole, Gaëlle Hogrel, Yang Lu, Sébastien Laurent, Marie Hemon, Johanne Aubé, Elodie Leroy, Erwan Roussel, Jacques Oberto, Didier Flament, Rémi Dulermo
Publikováno v:
mBio, Vol 15, Iss 4 (2024)
ABSTRACTThe mechanisms underpinning the replication of genomic DNA have recently been challenged in Archaea. Indeed, the lack of origin of replication has no deleterious effect on growth, suggesting that replication initiation relies on homologous re
Externí odkaz:
https://doaj.org/article/01a88b00d90d4f39b30b8fdbd903c460
Autor:
Clément Madru, Markel Martínez-Carranza, Sébastien Laurent, Alessandra C. Alberti, Maelenn Chevreuil, Bertrand Raynal, Ahmed Haouz, Rémy A. Le Meur, Marc Delarue, Ghislaine Henneke, Didier Flament, Mart Krupovic, Pierre Legrand, Ludovic Sauguet
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Replication Protein A (RPA) is a heterotrimeric single stranded DNA-binding protein with essential roles in DNA replication, recombination and repair. Little is known about the structure of RPA in Archaea, the third domain of life. By using
Externí odkaz:
https://doaj.org/article/8ae48732a3044f69b9e87147a45794c9
A complete guide to the theory and practice of volatility models in financial engineering Volatility has become a hot topic in this era of instant communications, spawning a great deal of research in empirical finance and time series econometrics. Pr
Publikováno v:
Frontiers in Psychology, Vol 13 (2022)
This study focuses on Automated Vehicles (AVs) interactions with pedestrians during road crossing situations. A dual-phase experiment was designed: one from the pedestrian’s perspective and the other one from the AV passenger’s point of view. Eig
Externí odkaz:
https://doaj.org/article/cb7d37d7a4fd46a2a3255bf716217b62
Publikováno v:
Revue économique. 51:703
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::620da6f7864f3bbf65dfc697300d3260
https://doi.org/10.2307/3503157
https://doi.org/10.2307/3503157