Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Sebastien Jacquemont"'
Autor:
Eya-Mist Rødgaard, Borja Rodríguez-Herreros, Abderrahim Zeribi, Kristian Jensen, Valérie Courchesne, Elise Douard, David Gagnon, Guillaume Huguet, Sebastien Jacquemont, Laurent Mottron
Publikováno v:
Molecular Autism, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Background Clinicians diagnosing autism rely on diagnostic criteria and instruments in combination with an implicit knowledge based on clinical expertise of the specific signs and presentations associated with the condition. This implicit kn
Externí odkaz:
https://doaj.org/article/f156ce5c0ff94870b5111790df82b259
Autor:
Adeniran Okewole, Vincent-Raphael Bourque, Sebastien Jacquemont, Varun Warrier, Simon Baron-Cohen
Publikováno v:
BJPsych Open, Vol 10, Pp S69-S69 (2024)
Aims This study investigated the relationship between common genetic variation and co-occurring mental health conditions among autistic individuals. Methods The study was conducted with the Simons Foundation Powering Autism Research (SPARK) dataset,
Externí odkaz:
https://doaj.org/article/80df8fb401dc418d8bfea90090eb5743
Autor:
Panhaneath Seng, Federica Alice Maria Montanaro, Hazel Maridith Barlahan Biag, Maria Jimena Salcedo-Arellano, Kyoungmi Kim, Matthew Dominic Ponzini, Flora Tassone, Andrea Schneider, Leonard Abbeduto, Angela John Thurman, David Hessl, Francois V. Bolduc, Sebastien Jacquemont, Sarah Lippé, Randi J. Hagerman
Publikováno v:
Frontiers in Psychology, Vol 15 (2024)
IntroductionMetformin has been used as a targeted treatment to potentially improve cognition and slow the typical IQ decline that occurs during development among individuals with fragile X syndrome (FXS). In this follow-up study, we are following the
Externí odkaz:
https://doaj.org/article/cb7ce96699c24474b763bd28cf2d2d6c
Autor:
Rackeb Tesfaye, Guillaume Huguet, Zoe Schmilovich, Thomas Renne, Mor Absa Loum, Elise Douard, Zohra Saci, Martineau Jean-Louis, Jean Luc Martineau, Rob Whelan, Sylvane Desrivieres, Andreas Heinz, Gunter Schumann, Caroline Hayward, Mayada Elsabbagh, Sebastien Jacquemont
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Sleep disturbance is prevalent in youth with Autism Spectrum Disorder (ASD). Researchers have posited that circadian dysfunction may contribute to sleep problems or exacerbate ASD symptomatology. However, there is limited genetic evidence of
Externí odkaz:
https://doaj.org/article/043345159f9b4b0e8409c27e10b39bc3
Autor:
Ramkumar Aishworiya, Mei-Hung Chi, Marwa Zafarullah, Guadalupe Mendoza, Matthew Dominic Ponzini, Kyoungmi Kim, Hazel Maridith Barlahan Biag, Angela John Thurman, Leonard Abbeduto, David Hessl, Jamie Leah Randol, Francois V. Bolduc, Sebastien Jacquemont, Sarah Lippé, Paul Hagerman, Randi Hagerman, Andrea Schneider, Flora Tassone
Publikováno v:
Cells, Vol 12, Iss 14, p 1920 (2023)
This study contributes to a greater understanding of the utility of molecular biomarkers to identify clinical phenotypes of fragile X syndrome (FXS). Correlations of baseline clinical trial data (molecular measures—FMR1 mRNA, CYFIP1 mRNA, MMP9 and
Externí odkaz:
https://doaj.org/article/0b6bc6c22d6f4eb0a59930c3348fbf5b
Autor:
Clara A. Moreau, Sebastian G. W. Urchs, Kumar Kuldeep, Pierre Orban, Catherine Schramm, Guillaume Dumas, Aurélie Labbe, Guillaume Huguet, Elise Douard, Pierre-Olivier Quirion, Amy Lin, Leila Kushan, Stephanie Grot, David Luck, Adrianna Mendrek, Stephane Potvin, Emmanuel Stip, Thomas Bourgeron, Alan C. Evans, Carrie E. Bearden, Pierre Bellec, Sebastien Jacquemont
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
The impact of neurodevelopmental mutations on functional brain connectivity is poorly understood. Here the authors identify thalamo-sensorimotor dysconnectivity dimensions shared across 16p11.2 and 22q11.2 copy number variants, autism and schizophren
Externí odkaz:
https://doaj.org/article/c8046adb9f7945e59d7f1cd01bd68a9a
Autor:
Randi Hagerman, Sebastien Jacquemont, Elizabeth Berry-Kravis, Vincent Des Portes, Andrew Stanfield, Barbara Koumaras, Gerd Rosenkranz, Alessandra Murgia, Christian Wolf, George Apostol, Florian von Raison
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract Fragile X syndrome (FXS) is the most common monogenic cause of inherited intellectual and developmental disabilities. Mavoglurant, a selective metabotropic glutamate receptor subtype-5 antagonist, has shown positive neuronal and behavioral e
Externí odkaz:
https://doaj.org/article/b0c86247e00a4aa7a01f18f018f9be46
Autor:
Robin G Walters, Lachlan J M Coin, Aimo Ruokonen, Adam J de Smith, Julia S El-Sayed Moustafa, Sebastien Jacquemont, Paul Elliott, Tõnu Esko, Anna-Liisa Hartikainen, Jaana Laitinen, Katrin Männik, Danielle Martinet, David Meyre, Matthias Nauck, Claudia Schurmann, Rob Sladek, Gudmar Thorleifsson, Unnur Thorsteinsdóttir, Armand Valsesia, Gerard Waeber, Flore Zufferey, Beverley Balkau, François Pattou, Andres Metspalu, Henry Völzke, Peter Vollenweider, Kári Stefansson, Marjo-Riitta Järvelin, Jacques S Beckmann, Philippe Froguel, Alexandra I F Blakemore
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58048 (2013)
The limited ability of common variants to account for the genetic contribution to complex disease has prompted searches for rare variants of large effect, to partly explain the 'missing heritability'. Analyses of genome-wide genotyping data have iden
Externí odkaz:
https://doaj.org/article/b391834b6bdd459fa5a7a4d8da996c62
Autor:
Clara A Moreau, Kuldeep Kumar, Annabelle Harvey, Guillaume Huguet, Sebastian G W Urchs, Laura M Schultz, Hanad Sharmarke, Khadije Jizi, Charles-Olivier Martin, Nadine Younis, Petra Tamer, Jean-Louis Martineau, Pierre Orban, Ana Isabel Silva, Jeremy Hall, Marianne B M van den Bree, Michael J Owen, David E J Linden, Sarah Lippé, Carrie E Bearden, Laura Almasy, David C Glahn, Paul M Thompson, Thomas Bourgeron, Pierre Bellec, Sebastien Jacquemont
Publikováno v:
Brain-A Journal of Neurology
Brain-A Journal of Neurology, In press, pp.awac315. ⟨10.1093/brain/awac315⟩
Brain, 146(4), 1686-1696. Oxford University Press
Brain-A Journal of Neurology, In press, pp.awac315. ⟨10.1093/brain/awac315⟩
Brain, 146(4), 1686-1696. Oxford University Press
Pleiotropy occurs when a genetic variant influences more than one trait. This is a key property of the genomic architecture of psychiatric disorders and has been observed for rare and common genomic variants. It is reasonable to hypothesize that the
Autor:
Cécile Louveau, Pierre Ellul, Anton Iftimovici, Julien Dubreucq, Charles Laidi, Quentin Leyrolle, Diane Purper-Ouakil, Sebastien Jacquemont, Stanislas Lyonnet, Catherine Barthélémy, Marie-Odile Krebs, Jing Bai, Paul Olivier, Boris Chaumette
Publikováno v:
Journal of Neural Transmission
Journal of Neural Transmission, 2023, Online ahead of print. ⟨10.1007/s00702-023-02586-w⟩
Journal of Neural Transmission, 2023, Online ahead of print. ⟨10.1007/s00702-023-02586-w⟩
International audience; On June 2022, the 2nd Webinar "Neurodevelopmental Disorders (NDD) without boundaries took place at the Imagine Institute in Paris and was broadcasted live and in replay. The aim of this webinar is to address NDD in a dimension