Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Sebastien Estaran"'
Autor:
Alain Chavanieu, Carine Alcon, Hervé Sentenac, Manuel Nieves-Cordones, Linda Jeanguenin, Isabelle Gaillard, Isabelle Chérel, Sebastien Estaran, Wojciech Szponarski, Sabine Zimmermann
Publikováno v:
Plant Physiology
Plant Physiology, American Society of Plant Biologists, 2014, 164 (3), pp.1415-29. ⟨10.1104/pp.113.229757⟩
Plant Physiology, American Society of Plant Biologists, 2014, 164 (3), pp.1415-29. ⟨10.1104/pp.113.229757⟩
Shaker K+ channels form the major K+ conductance of the plasma membrane in plants. They are composed of four subunits arranged around a central ion-conducting pore. The intracellular carboxy-terminal region of each subunit contains several regulatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc2a2d05fd69f171760ff8f953527079
https://hal.archives-ouvertes.fr/hal-00962147
https://hal.archives-ouvertes.fr/hal-00962147
Autor:
Romain Trouillard, François Hoh, Jad Rouhana, Alain Chavanieu, Yvan Boublik, André Padilla, Corinne Henriquet, Martine Pugnière, Sebastien Estaran, Aziz Kerkour, Jean Martinez
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, American Chemical Society, 2013, 56 (8497−8511), epub ahead of print. ⟨10.1021/jm4009357⟩
Journal of Medicinal Chemistry, American Chemical Society, 2013, 56 (8497−8511), epub ahead of print. ⟨10.1021/jm4009357⟩
International audience; By virtual screening using a fragment-based drug design (FBDD) approach, 33 fragments were selected within small pockets around interaction hot spots on the Sec7 surface of the nucleotide exchange factor Arno, and then their a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31662dc539a3675f1eebc4a2f9081aef
https://hal.archives-ouvertes.fr/hal-00905451
https://hal.archives-ouvertes.fr/hal-00905451
Autor:
Martine Pugnière, Sana Bakari, Sebastien Estaran, Alain Chavanieu, Jad Rouhana, Stephane Delbecq, André Padilla, Joël Chopineau, Yvan Boublik
Publikováno v:
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2013, 288 (7), pp.4659-72. ⟨10.1074/jbc.M112.391748⟩
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2013, 288 (7), pp.4659-72. ⟨10.1074/jbc.M112.391748⟩
International audience; The GDP/GTP nucleotide exchange of Arf1 is catalyzed by nucleotide exchange factors (GEF), such as Arno, which act through their catalytic Sec7 domain. This exchange is a complex mechanism that undergoes conformational changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7454a0bc2581b37e9128037548a79e2
https://pubmed.ncbi.nlm.nih.gov/23255605
https://pubmed.ncbi.nlm.nih.gov/23255605
Autor:
Mathilde Folacci, Sébastien Estaran, Claudine Ménard, Anaïs Bertaud, Matthieu Rousset, Julien Roussel, Jean-Baptiste Thibaud, Michel Vignes, Alain Chavanieu, Pierre Charnet, Thierry Cens
Publikováno v:
Membranes, Vol 13, Iss 1, p 96 (2023)
Cav2.1 channels are expressed throughout the brain and are the predominant Ca2+ channels in the Purkinje cells. These cerebellar neurons fire spontaneously, and Cav2.1 channels are involved in the regular pacemaking activity. The loss of precision of
Externí odkaz:
https://doaj.org/article/34273affecda40d58b4ce287f727f680
Publikováno v:
Cells, Vol 9, Iss 2, p 286 (2020)
Background: Head and neck squamous cell carcinoma (HNSCC) is one of the leading causes of cancer-related deaths and calls for new druggable targets. We have previously highlighted the critical role of ADP-ribosylation factor-1 (Arf1) activation in HN
Externí odkaz:
https://doaj.org/article/333ff86a38694d73b36f50d9cc6a05a6