Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sebastien, Burel"'
Autor:
Nicholas J. Viney, Shuling Guo, Li‐Jung Tai, Brenda F. Baker, Mariam Aghajan, Shiangtung W. Jung, Rosie Z. Yu, Sheri Booten, Heather Murray, Todd Machemer, Sebastien Burel, Sue Murray, Gustavo Buchele, Sotirios Tsimikas, Eugene Schneider, Richard S. Geary, Merrill D. Benson, Brett P. Monia
Publikováno v:
ESC Heart Failure, Vol 8, Iss 1, Pp 652-661 (2021)
Abstract Aims Amyloidogenic transthyretin (ATTR) amyloidosis is a fatal disease characterized by progressive cardiomyopathy and/or polyneuropathy. AKCEA‐TTR‐LRx (ION‐682884) is a ligand‐conjugated antisense drug designed for receptor‐mediat
Externí odkaz:
https://doaj.org/article/3297462a8e6e4c1081fbb6040b37c72e
Autor:
Thomas A, Zanardi, Birgit, Korbmacher, Laura, Boone, Jeffrey A, Engelhardt, Yanfeng, Wang, Sebastien, Burel, Bobby, Prill, Mariam, Aghajan, Shuling, Guo, Scott P, Henry
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 377(1)
Cellular uptake of antisense oligonucleotides (ASOs) is one of the main determinants of in vivo activity and potency. A significant advancement in improving uptake into cells has come through the conjugation of ASOs to triantenarry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8570ade61e834d278421b8b04acb6d94
https://pubmed.ncbi.nlm.nih.gov/33431610
https://pubmed.ncbi.nlm.nih.gov/33431610