Mendelian Randomization in Pulmonary Arterial Hypertension: Unveiling Early Insights With Promise for Future Discoveries

Autor: Steeve Provencher, Benoit J. Arsenault, Sebastien Bonnet

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 6 (2024)

Externí odkaz: https://doaj.org/article/ea7f2ceb3d944ed897945915f799ea75

Perspectives on Cardiopulmonary Critical Care for Patients With COVID‐19: From Members of the American Heart Association Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation

Autor: Bradley A. Maron, Mark T. Gladwin, Sebastien Bonnet, Vinicio De Jesus Perez, Sarah M. Perman, Paul B. Yu, Fumito Ichinose

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 14 (2020)

Externí odkaz: https://doaj.org/article/098a9e88b53948e7b884b49656a93f67

Identification of LTBP-2 as a plasma biomarker for right ventricular dysfunction in human pulmonary arterial hypertension

Autor: Olivier Boucherat, Tetsuro Yokokawa, Vinod Krishna, Shanker Kalyana-Sundaram, Sandra Martineau, Sandra Breuils-Bonnet, Nabil Azhar, Fany Bonilla, David Gutstein, François Potus, Allan Lawrie, Jey Jeyaseelan, Steeve Provencher, Sebastien Bonnet

Publikováno v: Nature Cardiovascular Research. 1:748-760

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a38d54e6485fe5a3b9b0ac26223cc1e5
https://doi.org/10.1038/s44161-022-00113-w

Targeting Wnt-ß-Catenin-FOSL Signaling Ameliorates Right Ventricular Remodeling

Autor: Sreenath Reddy Nayakanti, Aleksandra Friedrich, Poonam Sarode, Leili Jafari, Giovanni Maroli, Mario Boehm, Alice Bourgeois, Yann Grobs, Fatemeh Khassafi, Carsten Kuenne, Stefan Guenther, Swati Dabral, Jochen Wilhelm, Astrid Weiss, Astrid Wietelmann, Baktybek Kojonazarov, Wiebke Janssen, Mario Looso, Frances de Man, Steeve Provencher, Khodr Tello, Werner Seeger, Sebastien Bonnet, Rajkumar Savai, Ralph T. Schermuly, Soni Savai Pullamsetti

Publikováno v: Circulation Research, 132(11), 1468-1485. Lippincott Williams and Wilkins
Nayakanti, S R, Friedrich, A, Sarode, P, Jafari, L, Maroli, G, Boehm, M, Bourgeois, A, Grobs, Y, Khassafi, F, Kuenne, C, Guenther, S, Dabral, S, Wilhelm, J, Weiss, A, Wietelmann, A, Kojonazarov, B, Janssen, W, Looso, M, de Man, F, Provencher, S, Tello, K, Seeger, W, Bonnet, S, Savai, R, Schermuly, R T & Pullamsetti, S S 2023, ' Targeting Wnt-ß-Catenin-FOSL Signaling Ameliorates Right Ventricular Remodeling ', Circulation Research, vol. 132, no. 11, pp. 1468-1485 . https://doi.org/10.1161/CIRCRESAHA.122.321725

Background: The ability of the right ventricle (RV) to adapt to an increased pressure afterload determines survival in patients with pulmonary arterial hypertension. At present, there are no specific treatments available to prevent RV failure, except

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dca445c493e7f5101cd83abafca2c3ed
https://research.vumc.nl/en/publications/0ba7346f-29dc-4c64-b99e-3989f15cebaf

Commentary on: Xbp1s-Ddit3, DNA damage and pulmonary hypertension

Autor: Sarah-Eve, Lemay, Sebastien, Bonnet, François, Potus

Publikováno v: Clinical Science (London, England : 1979)

Pulmonary hypertension (PH) is a life-threatening disease characterized by vascular remodeling. Exploring new therapy target is urgent. The purpose of the present study is to investigate whether and how spliced x-box binding protein 1 (xbp1s), a key

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad3e0473ba88f1d03d1774d11b3ea94d
https://doi.org/10.1042/cs20211095