mGlu receptors in the treatment of Parkinson's disease and L-DOPA-induced dyskinesia

Autor: Sebastianutto, Irene, Cenci, Maria Angela

Publikováno v: In Current Opinion in Pharmacology February 2018 38:81-89

Validation of an improved scale for rating l-DOPA-induced dyskinesia in the mouse and effects of specific dopamine receptor antagonists

Autor: Sebastianutto, Irene, Maslava, Natallia, Hopkins, Corey R., Cenci, M. Angela

Publikováno v: In Neurobiology of Disease December 2016 96:156-170

D1-mGlu5 heteromers mediate noncanonical dopamine signaling in Parkinson’s disease

Autor: Sebastianutto, Irene, Goyet, Elise, Andreoli, Laura, Font-Ingles, Joan, Moreno-Delgado, David, Bouquier, Nathalie, Jahannault-Talignani, Céline, Moutin, Enora, Di Menna, Luisa, Pin, Jean-Philippe, Maslava, Natallia, Fagni, Laurent, Nicoletti, Ferdinando, Ango, Fabrice, Cenci, M. Angela, Perroy, Julie

Publikováno v: Journal of Clinical Investigation
Journal of Clinical Investigation, 2020, 130 (3), pp.1168-1184. ⟨10.1172/JCI126361⟩
Journal of Clinical Investigation, American Society for Clinical Investigation, 2020, 130 (3), pp.1168-1184. ⟨10.1172/JCI126361⟩

International audience; Dopamine receptor D1 modulates glutamatergic transmission in cortico-basal ganglia circuits and represents a major target of L-DOPA therapy in Parkinson's disease. Here we show that D1 and metabotropic glutamate type 5 (mGlu5)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ba6fa4dec2568b15569da8c43c9aadcc
https://doi.org/10.1172/JCI126361

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