Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Sebastiano Macheda"'
Autor:
Andrea Bruni, Federico Longhini, Sebastiano Macheda, Eugenio Biamonte, Pino Pasqua, Giuseppe Neri, Maria Laura Guzzo, Eugenio Garofalo, Calabria COVID-ICU Network authors, Antonio Caroleo, Paolo Chirico, Angela Corea, Silvia Corrado, Pierfrancesco De Luca, Federica Fazio, Martina Fontanella, Annamaria Froio, Cesira Greco, Giusy Guzzi, Marco Pignataro, Sara Rizzo, Claudia Roccia, Giuseppe Saraco, Ugo Settimio, Marco Tescione, Eugenio Vadalà, Michele Ippolito, Cosimo Stefano, Pietro Maglio, Mario Pezzi, Simona Tiburzi
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
IntroductionAfter the rapid surge of a novel coronavirus (SARS-CoV-2) in 2020 anti-SARS-CoV-2 vaccines have been developed to prevent the development of critical forms of COVID-19 leading to Intensive Care Unit (ICU) admission. The possibility of ICU
Externí odkaz:
https://doaj.org/article/49deb27d8ae14eeaaa05aaeee5e800fa
Autor:
Marco Tescione, Eugenio Vadalà, Graziella Marano, Andrea Bruni, Eugenio Garofalo, Ovidia Lavalle, Federico Longhini, Enzo Battaglia, Nicola Polimeni, Demetrio Labate, Sarah Caracciolo, Francesco Giordano, Massimo Caracciolo, Sebastiano Macheda
Publikováno v:
Clinical Case Reports, Vol 9, Iss 3, Pp 1049-1054 (2021)
Abstract In COVID‐19 patients receiving enoxaparin and antiplatelets therapy, aggregometry and thromboelastography might be considered an adjunctive tool to identify the time to perform procedures at risk of bleeding, such as tracheostomy.
Externí odkaz:
https://doaj.org/article/39d42ee553c540eeb8ad470ce363346c
Autor:
Antonino De Lorenzo, Maria Grazia Tarsitano, Carmela Falcone, Laura Di Renzo, Lorenzo Romano, Sebastiano Macheda, Anna Ferrarelli, Demetrio Labate, Marco Tescione, Federico Bilotta, Paola Gualtieri
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-8 (2020)
Abstract Background Obesity and steatosis are associated with COVID-19 severe pneumonia. Elevated levels of pro-inflammatory cytokines and reduced immune response are typical of these patients. In particular, adipose tissue is the organ playing the c
Externí odkaz:
https://doaj.org/article/896508ab48f743408ec8baa8455e79dc
Autor:
Eugenio Garofalo, Gianmaria Cammarota, Giuseppe Neri, Sebastiano Macheda, Eugenio Biamonte, Pino Pasqua, Maria Laura Guzzo, Federico Longhini, Andrea Bruni
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 20, p 5992 (2022)
(1) Background: In COVID-19 patients, the occurrence of thromboembolic complications contributes to disease progression and mortality. In patients at increased risk for thrombotic complications, therapeutic enoxaparin should be considered. However, c
Externí odkaz:
https://doaj.org/article/6527aed17b124e26a0e1ebd58de8be34
Autor:
Valerio Nardone, Rocco Giannicola, Giovanna Bianco, Diana Giannarelli, Paolo Tini, Pierpaolo Pastina, Antonia Consuelo Falzea, Sebastiano Macheda, Michele Caraglia, Amalia Luce, Silvia Zappavigna, Luciano Mutti, Luigi Pirtoli, Antonio Giordano, Pierpaolo Correale
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Peripheral-immune-checkpoint blockade (P-ICB) with mAbs to PD-1 (nivolumab and pembrolizumab) or PD-L1 (atezolizumab, durvalumab, avelumab) alone or combination with chemotherapy represents a novel active treatment for mNSCLC patients. However, this
Externí odkaz:
https://doaj.org/article/44c6f43b72ed4333ad3dfa420b56c3ce
Autor:
Massimo Caracciolo, Pierpaolo Correale, Carmelo Mangano, Giuseppe Foti, Carmela Falcone, Sebastiano Macheda, Maria Cuzzola, Marco Conte, Antonella Consuelo Falzea, Eleonora Iuliano, Antonella Morabito, Michele Caraglia, Nicola Polimeni, Anna Ferrarelli, Demetrio Labate, Marco Tescione, Laura Di Renzo, Gaetano Chiricolo, Lorenzo Romano, Antonino De Lorenzo
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Lack of specific antiviral treatment for COVID-19 has resulted in long hospitalizations and high mortality rate. By harnessing the regulatory effects of adenosine on inflammatory mediators, we have instituted a new therapeutic treatment with inhaled
Externí odkaz:
https://doaj.org/article/05c5ea14673c410a88457a775b784ddb
Autor:
Massimo Caracciolo, Sebastiano Macheda, Demetrio Labate, Marco Tescione, Stefano La Scala, Eugenio Vadalà, Rosalba Squillaci, Francesco D’Aleo, Antonella Morabito, Cristina Garreffa, Maria Concetta Marciano, Esther N. Oliva
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Severe cases of COVID-19 present with serious lung inflammation, acute respiratory distress syndrome and multiorgan damage. SARS-CoV-2 infection is associated with high cytokine levels, including interleukin-6 and certain subsets of immune cells, in
Externí odkaz:
https://doaj.org/article/a40e31b4e59345abb0c1a5a741ef9b76
Autor:
Pierpaolo Correale, Massimo Caracciolo, Federico Bilotta, Marco Conte, Maria Cuzzola, Carmela Falcone, Carmelo Mangano, Antonella Consuelo Falzea, Eleonora Iuliano, Antonella Morabito, Giuseppe Foti, Antonio Armentano, Michele Caraglia, Antonino De Lorenzo, Michail Sitkovsky, Sebastiano Macheda
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0239692 (2020)
BackgroundSARS-Cov2 infection may trigger lung inflammation and acute-respiratory-distress-syndrome (ARDS) that requires active ventilation and may have fatal outcome. Considering the severity of the disease and the lack of active treatments, 14 pati
Externí odkaz:
https://doaj.org/article/c0fee749597d490eb62cc6d4417d8d39
Autor:
Carmela Falcone, Massimo Caracciolo, Pierpaolo Correale, Sebastiano Macheda, Eugenio Giuseppe Vadalà, Stefano La Scala, Marco Tescione, Roberta Danieli, Anna Ferrarelli, Maria Grazia Tarsitano, Lorenzo Romano, Antonino De Lorenzo
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 9, p 3045 (2020)
Coronavirus disease 2019 (COVID-19) patients can develop interstitial pneumonia, which, in turn, can evolve into acute respiratory distress syndrome (ARDS). This is accompanied by an inflammatory cytokine storm. severe acute respiratory syndrome coro
Externí odkaz:
https://doaj.org/article/c11bb725b00e4eda9b88937b5d47d90e
Autor:
Paola Gualtieri, Carmela Falcone, Lorenzo Romano, Sebastiano Macheda, Pierpaolo Correale, Pietro Arciello, Nicola Polimeni, Antonino De Lorenzo
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 13, p 4670 (2020)
Obesity is a characteristic of COVID-19 patients and the risk of malnutrition can be underestimated due to excess of fat: a paradoxical danger. Long ICU hospitalization exposes patients to a high risk of wasting and loss of lean body mass. The comple
Externí odkaz:
https://doaj.org/article/67a521758d874189804b08b079e58903