Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Sebastiano, Colombatto"'
Autor:
Giovanni De Marco, Annarosa Lomartire, Umberto Manera, Antonio Canosa, Maurizio Grassano, Federico Casale, Giuseppe Fuda, Paolina Salamone, Maria Teresa Rinaudo, Sebastiano Colombatto, Cristina Moglia, Adriano Chiò, Andrea Calvo
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract The aetiology of Amyotrophic Lateral Sclerosis (ALS) is still poorly understood. The discovery of genetic forms of ALS pointed out the mechanisms underlying this pathology, but also showed how complex these mechanisms are. Excitotoxicity is
Externí odkaz:
https://doaj.org/article/e0f957fdf779424b97ac6858f58e9b86
Autor:
Giovanni Di Maira, Beatrice Foglia, Lucia Napione, Cristian Turato, Marina Maggiora, Salvatore Sutti, Erica Novo, Maria Alvaro, Riccardo Autelli, Sebastiano Colombatto, Federico Bussolino, Patrizia Carucci, Silvia Gaia, Chiara Rosso, Alessandra Biasiolo, Patrizia Pontisso, Elisabetta Bugianesi, Emanuele Albano, Fabio Marra, Maurizio Parola, Stefania Cannito
Oncostatin M (OSM) is a pleiotropic cytokine of the interleukin (IL)-6 family that contributes to the progression of chronic liver disease. Here we investigated the role of OSM in the development and progression of hepatocellular carcinoma (HCC) in n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d85c5711c6f83ae7b4757c6b46a257f
http://hdl.handle.net/11577/3420904
http://hdl.handle.net/11577/3420904
Autor:
Giovanni DE MARCO, Annarosa Lomartire, Umberto Manera, Antonio Canosa, Maurizio Grassano, Federico Casale, Giuseppe Fuda, Paolina Salamone, Maria Teresa Rinaudo, Sebastiano Colombatto, Cristina Moglia, Adriano Chiò, Andrea Calvo
The aetiology of Amyotrophic Lateral Sclerosis (ALS), a fatal and incurable disease caused by motor neuron degeneration, is still poorly understood. The discovery of genetic forms of ALS helped to shed light on the mechanisms underlying this patholog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29241db339e945dbd25032069dad67fc
https://doi.org/10.21203/rs.3.rs-220372/v1
https://doi.org/10.21203/rs.3.rs-220372/v1
Autor:
G. Maira, B. Foglia, L. Napione, C. Turato, M. Maggiora, S. Sutti, Maria Alvaro, Riccardo Autelli, Sebastiano Colombatto, Federico Bussolino, Patrizia Carucci, Silvia Gaia, Chiara Rosso, Alessandra Biasiolo, Patrizia Pontisso, Elisabetta Bugianesi, Emanuele Albano, Fabio Marra, Maurizio Parola, Stefania Cannito
Publikováno v:
Digestive and Liver Disease. 54:S41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa3210e026d5b10742f6fa8b9225acb8
https://doi.org/10.1016/j.dld.2022.01.081
https://doi.org/10.1016/j.dld.2022.01.081
Autor:
Federico Bussolino, Santina Quarta, Sebastiano Colombatto, Stefania Cannito, Patrizia Pontisso, G. Villano, María L. Martínez-Chantar, Mariagrazia Ruvoletto, Silvano Fasolato, Erica Novo, Fernando Lopitz-Otsoa, Fabrizio Pin, Cristian Turato, Emanuele Albano, Salvatore Sutti, Beatrice Foglia, Teresa C. Delgado, E. Morello, Maurizio Parola, Giacomo Zanus, David Fernández-Ramos, Lucia Napione
Publikováno v:
Cancers
Volume 11
Issue 12
Volume 11
Issue 12
Background: SerpinB3 (SB3) is a hypoxia and hypoxia-inducible factor (HIF)-2&alpha
dependent cysteine-protease inhibitor up-regulated in hepatocellular carcinoma (HCC), released by cancer cells and able to stimulate proliferation and epithelial-
dependent cysteine-protease inhibitor up-regulated in hepatocellular carcinoma (HCC), released by cancer cells and able to stimulate proliferation and epithelial-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5caf5edbbf1c30699d7ba00901099f49
http://hdl.handle.net/2318/1721865
http://hdl.handle.net/2318/1721865
Autor:
Bruno Torchio, Manuela Motta, Riccardo Autelli, Monica Ievolella, Antonella Miglietta, Stefania Cannito, Francesca Bozzo, Claudia Bocca, Maurizio Parola, Claudia Paternostro, Sebastiano Colombatto, Luciano Mosso
Publikováno v:
Expert Opinion on Therapeutic Targets. 18:121-135
Cyclooxygenase-2 (COX-2) is overexpressed in several malignancies and is implicated in breast cancer progression.We investigated whether changes in COX-2 expression may affect epithelial-to-mesenchymal transition (EMT) and then invasive potential of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aad09ab843548a2a6d5fde3d1c93af0a
https://doi.org/10.1517/14728222.2014.860447
https://doi.org/10.1517/14728222.2014.860447
Autor:
Elisabetta Aldieri, Dario Ghigo, Sebastiano Colombatto, Manuela Polimeni, Joanna Kopecka, Mauro Prato, Giulia Rossana Gulino, Elena Gazzano
Publikováno v:
Environmental Health Perspectives
Background: Chrysotile asbestos accounts for > 90% of the asbestos used worldwide, and exposure is associated with asbestosis (asbestos-related fibrosis) and other malignancies; however, the molecular mechanisms involved are not fully understood. A c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55e727fe9f67ae81f98ec29dd542cd63
https://hdl.handle.net/2318/1887629
https://hdl.handle.net/2318/1887629
Autor:
Lorenzo Valfrè di Bonzo, Stefania Cannito, Erica Novo, Chiara Busletta, Sebastiano Colombatto, Maurizio Parola
Publikováno v:
Antioxidants & Redox Signaling. 12:1383-1430
Epithelial to mesenchymal transition (EMT) is a fundamental process, paradigmatic of the concept of cell plasticity, that leads epithelial cells to lose their polarization and specialized junctional structures, to undergo cytoskeleton reorganization,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d7f9b82ccb4427cd03a7f7691e6d5e7
https://doi.org/10.1089/ars.2009.2737
https://doi.org/10.1089/ars.2009.2737
Publikováno v:
Chemico-Biological Interactions. 183:187-193
We previously reported that conjugated linoleic acid (CLA), a naturally occurring fatty acid, inhibits the growth of ERalpha(+) MCF-7 and ERalpha(-) MDA-MB-231 human breast cancer cells by negative modulation of the ERK/MAPK pathway and apoptosis ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09e6c84310805960d14d99efef2fc22
https://doi.org/10.1016/j.cbi.2009.09.022
https://doi.org/10.1016/j.cbi.2009.09.022
Autor:
Stefania Cannito, Sebastiano Colombatto, Maurizio Parola, Erica Novo, Lorenzo Valfrè di Bonzo
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 41:2089-2093
Hepatic myofibroblasts constitute a heterogeneous population of highly proliferative, pro-fibrogenic, pro-inflammatory, pro-angiogenic and contractile cells that sustain liver fibrogenesis and then fibrotic progression of chronic liver diseases of di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95858bb96b3ddb7503be8e1f50241c0c
https://doi.org/10.1016/j.biocel.2009.03.010
https://doi.org/10.1016/j.biocel.2009.03.010