Výsledky vyhledávání - "Sebastian-Alexander Stamatis"

Systems-level investigation of mucopolysaccharidosis IIIA identifies deficient synaptic activity as a key driver of disease progression

Autor: Alon M Douek, Abbas Salavaty, Florian Kreuder, Sebastian-Alexander Stamatis, Joel R Steele, Iresha Hanchapola, Anup D Shah, Ralf B Schittenhelm, Mirana Ramialison, Peter D Currie, Jan Kaslin

Mucopolysaccharidoses are lysosomal storage diseases that collectively represent a major cause of lethal, treatment-refractory childhood dementias 1–7 Clinically-useful interventions are hampered due to an incomplete understanding of their neuropat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f6830f198a248d2772208598c3f9520
https://doi.org/10.1101/2022.10.03.510585

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An engineered sgsh Mutant Zebrafish recapitulates molecular and behavioural pathobiology of sanfilippo syndrome A/MPS IIIA

Autor: Sebastian-Alexander Stamatis, Minna-Liisa Änkö, Jason Henry, Alon M. Douek, Mitra Khabooshan, Florian Kreuder, Jan Kaslin, Donald Wlodkowic, Georg Ramm

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 11
International Journal of Molecular Sciences, Vol 22, Iss 5948, p 5948 (2021)

Mucopolysaccharidosis IIIA (MPS IIIA, Sanfilippo syndrome type A), a paediatric neurological lysosomal storage disease, is caused by impaired function of the enzyme N-sulfoglucosamine sulfohydrolase (SGSH) resulting in impaired catabolism of heparan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dc56af47e14587a37c7fb7b49a31682
https://trepo.tuni.fi/handle/10024/142583

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An Engineered

Autor: Alon M, Douek, Mitra, Amiri Khabooshan, Jason, Henry, Sebastian-Alexander, Stamatis, Florian, Kreuder, Georg, Ramm, Minna-Liisa, Änkö, Donald, Wlodkowic, Jan, Kaslin

Publikováno v: International Journal of Molecular Sciences

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::790271bcd5174cb996bea00e1b7c2584
https://pubmed.ncbi.nlm.nih.gov/34073041

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RNA-induced inflammation and migration of precursor neurons initiates neuronal circuit regeneration in zebrafish

Autor: Gilles Vanwalleghem, Madara Ratnadiwakara, Alon M. Douek, Mitra Khabooshan, Hozana A. Castillo, Ethan K. Scott, Sebastian Alexander Stamatis, Jan Kaslin, Emily K. Don, Celia Vandestadt, Minna-Liisa Änkö, Mei Li, Keith E. Schulze

Publikováno v: Developmental Cell. 56:2364-2380.e8

Tissue regeneration and functional restoration after injury are considered as stem- and progenitor-cell-driven processes. In the central nervous system, stem cell-driven repair is slow and problematic because function needs to be restored rapidly for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d682ef89f58b1a1cbd24ea2e2fab80
https://doi.org/10.1016/j.devcel.2021.07.021

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Regeneration of the Rhopalium and the Rhopalial Nervous System in the Box Jellyfish Tripedalia cystophora

Autor: Sebastian-Alexander Stamatis, Katrine Worsaae, Anders Garm

Publikováno v: The Biological bulletin. 234(1)

Cubozoans have the most intricate visual apparatus within Cnidaria. It comprises four identical sensory structures, the rhopalia, each of which holds six eyes of four morphological types. Two of these eyes are camera-type eyes that are, in many ways,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::464c8dc946869f2178bc7faa059c7ec0
https://pubmed.ncbi.nlm.nih.gov/29694798

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