Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sebastian Zimny"'
Autor:
Sebastian Zimny, Hélène Bourhis, Sabine Weber, Florian Paul Reiter, Simon Hohenester, Eduard Kraft, Isabelle Mohr, Uta Merle, Karl Heinz Weiss, Gerald Denk
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 18, Iss 1, Pp 1-11 (2023)
Abstract Background Wilson disease (WD) is a rare, hereditary disorder of copper metabolism. Due to its variable symptoms and manifestations, diagnosis remains challenging. Affected patients must obtain lifelong medical treatment, as the disease is f
Externí odkaz:
https://doaj.org/article/60ce7b8d9bc1475b9c199498c8a67f43
Autor:
Sebastian Zimny, Dennis Koob, Jingguo Li, Ralf Wimmer, Tobias Schiergens, Jutta Nagel, Florian Paul Reiter, Gerald Denk, Simon Hohenester
Publikováno v:
Cells, Vol 11, Iss 15, p 2344 (2022)
Bile salts accumulating during cholestatic liver disease are believed to promote liver fibrosis. We have recently shown that chenodeoxycholate (CDC) induces expansion of hepatic stellate cells (HSCs) in vivo, thereby promoting liver fibrosis. Mechani
Externí odkaz:
https://doaj.org/article/9787ff77cb1348e39f8f2292d3600cb3
Autor:
Marlen Spirk, Sebastian Zimny, Maximilian Neumann, Nichole McMullen, Christopher J. Sinal, Christa Buechler
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 20, p 7555 (2020)
The chemokine chemerin exists as C-terminally processed isoforms whose biological functions are mostly unknown. A highly active human chemerin variant (huChem-157) was protective in experimental hepatocellular carcinoma (HCC) models. Hepatic stellate
Externí odkaz:
https://doaj.org/article/b90c779833c6420298fc3db80e3f0281
Autor:
Monika Bischoff, Sebastian Zimny, Sebastian Feiner, Johannes Sauter, Svenja Sydor, Gerald Denk, Jutta M. Nagel, Gert Bischoff, Christian Rust, Simon Hohenester
Publikováno v:
European Journal of Nutrition. 61:2725-2735
Purpose Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic syndrome. Particularly morbidly obese patients are at risk of developing progressive liver disease. Nutritional and lifestyle intervention is recommended
Autor:
Dennis Koob, Judith Nagel, Sebastian Zimny, Jingguo Li, Renate Artmann, Ralf Wimmer, Gerald Denk, Martin Roderfeld, Elke Roeb, Hans Zischka, Simon Hohenester
Publikováno v:
Journal of Hepatology. 77:S602-S603
Publikováno v:
Journal of Hepatology. 73:S525-S526
Autor:
Lisa Rein-Fischboeck, Rebekka Pohl, Thomas S. Weiss, Sabrina Krautbauer, Christa Buechler, Sebastian Zimny, Elisabeth M. Haberl
Publikováno v:
Experimental and molecular pathology. 103(1)
Chemokine (CC-motif) receptor-like 2 (CCRL2) is a decoy receptor and regulates the local responses of the chemokine chemerin. Recently our group has shown that the functional chemerin receptor, chemokine-like receptor 1 (CMKLR1), correlates with fibr
Autor:
Maximilian Neumann, Lisa Rein-Fischboeck, Rebekka Pohl, Elisabeth M. Haberl, Thomas S. Weiss, Kristina Eisinger, Sebastian Zimny, Sabrina Krautbauer, Christa Buechler
Publikováno v:
Molecular and cellular biochemistry. 428(1-2)
Tubulin alpha 8 (TUBA8) is highly abundant in murine liver tumors suggesting a role in hepatocellular carcinoma (HCC). Non-alcoholic steatohepatitis (NASH) is a risk factor for HCC. In mice that are fed with a methionine-choline deficient diet for tw