Zobrazeno 1 - 10
of 205
pro vyhledávání: '"Sebastian Weis"'
Autor:
Christian von Loeffelholz, René Winkler, Cynthia Weigel, Eva-Maria Piskor, Wolfgang Vivas, Falk Rauchfuß, Utz Settmacher, Ignacio Rubio, Sebastian Weis, Markus H. Gräler, Michael Bauer, Christian Kosan
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110133- (2024)
Summary: Sepsis is a life-threatening condition caused by dysregulated host responses to infection. Myeloid cell accumulation and lymphocyte decline are widely recognized phenomena in septic patients. However, the fate of specific immune cells remain
Externí odkaz:
https://doaj.org/article/dff136deb42c4878b3c89f7959d4579e
Autor:
Stefan Kluge, Alexander Zarbock, Patrick Meybohm, Christian Putensen, Stefan Hagel, Mathias W Pletz, Michael Bauer, Christian Jung, Markus A Weigand, Thorsten Brenner, Markus Heim, Stefan Münster, Sven Bercker, Sandra Fiedler, Frank Bloos, Maria Deja, Christian Ertmer, Peter Rosenberger, Helene Häberle, Jochen Dutzmann, Charlotte Ling, Andreas Güldner, Johannes Ehler, Sebastian Weis, Nicole Brillinger, Sebastian Decker, Philipp Franken, Alexander Vogt, Tobias Lahmer, Silke Fortenbach, Stefan John, Marc M. Berger, Axel Nierhaus, Friedhelm Bach, Raphael Bruno, Michael Zoller, Sandra Frank, Sarah Müller, Markus Feußner, Heinrich V Groesdonk, Ulrich Frey, Jan-Martin Wischermann, Mareike Otto, Matthias Lindner, Jan Heyckendorf, Caterina Reuchsel, Bernd Reichmann
Publikováno v:
BMJ Open, Vol 14, Iss 4 (2024)
Introduction Herpes simplex virus (HSV) is frequently detected in the respiratory tract of mechanically ventilated patients and is associated with a worse outcome. The aim of this study is to determine whether antiviral therapy in HSV-positive patien
Externí odkaz:
https://doaj.org/article/c84813873bba43d0993e3e14947b10fa
Autor:
Peter Schlattmann, Thomas Lehmann, Tim Rahmel, Johannes Roth, Peter Kranke, Frank M Brunkhorst, Andreas Greinacher, Patrick Meybohm, Philipp Helmer, Stefan Hagel, Florian Rißner, Michael Bauer, Matthias Gründling, Sven-Olaf Kuhn, Christian Fuchs, Luis Ferreira Moita, Frank Bloos, Matthias Michael, Ulrike Schumacher, Matthias Unterberg, Daniel Thomas-Rüddel, Christiane Helbig, Johannes Ehler, Heiko Schenk, Thomas Köcher, Markus Gräler, Ann-Julika Heger, Sebastian Weis, Karen Dlubatz, Jakob Hammersen, Katja Leonhardt, René Markgraf, Franziska Röstel, Nicole Schwarze, Mariann Städtler, Wolfgang Vivas-Varela, Andre Hagedorn, Andrea Wittkowski, Florian Rumpf, Tobias Haas, Sebastian Hottenrott, Eva Kranke, Marianne Neuf, Anke Reppchen, Daniel Röder, Julius Schmidt
Publikováno v:
BMJ Open, Vol 14, Iss 4 (2024)
Introduction Sepsis remains the major cause of death among hospitalised patients in intensive care. While targeting sepsis-causing pathogens with source control or antimicrobials has had a dramatic impact on morbidity and mortality of sepsis patients
Externí odkaz:
https://doaj.org/article/61a05aa5bd5545d9812046f23ab53e28
Autor:
Sindy Burgold-Voigt, Elke Müller, David Zopf, Stefan Monecke, Sascha D. Braun, Katrin Frankenfeld, Michael Kiehntopf, Sebastian Weis, Thomas Schumacher, Mathias W. Pletz, Ralf Ehricht, The CoNAN Study Group
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Strategies to contain the current SARS-CoV-2 pandemic rely, beside vaccinations, also on molecular and serological testing. For any kind of assay development, screening for the optimal antigen is essential. Here we describe the verification
Externí odkaz:
https://doaj.org/article/e7e609add20a4237871302e761d3445e
Autor:
Annika Licht, Wibke Wetzker, Juliane Scholz, André Scherag, Sebastian Weis, Mathias W Pletz, Michael Bauer, Petra Dickmann, CoNAN study group
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0292248 (2023)
BackgroundQuarantine is one of the most effective interventions to contain an infectious disease outbreak, yet it is one of the most disruptive. We investigated the quarantine of an entire village to better understand risk communication requirements
Externí odkaz:
https://doaj.org/article/566dd2723ed24161b2990518fcae2673
Autor:
Clara Schnizer, Nico Andreas, Wolfgang Vivas, Thomas Kamradt, Michael Baier, Michael Kiehntopf, Stefan Glöckner, André Scherag, Bettina Löffler, Steffi Kolanos, Joel Guerra, Mathias W. Pletz, Sebastian Weis
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Understanding persistent cellular and humoral immune responses to SARS-CoV-2 will be of major importance to terminate the ongoing pandemic. Here, we assessed long-term immunity in individuals with mild COVID-19 up to 1 year after a localized SARS-CoV
Externí odkaz:
https://doaj.org/article/acef7df52df64345a308d7009deb5ad7
Autor:
Angelo Ferreira Chora, Dora Pedroso, Eleni Kyriakou, Nadja Pejanovic, Henrique Colaço, Raffaella Gozzelino, André Barros, Katharina Willmann, Tiago Velho, Catarina F Moita, Isa Santos, Pedro Pereira, Silvia Carvalho, Filipa Batalha Martins, João A Ferreira, Sérgio Fernandes de Almeida, Vladimir Benes, Josef Anrather, Sebastian Weis, Miguel P Soares, Arie Geerlof, Jacques Neefjes, Michael Sattler, Ana C Messias, Ana Neves-Costa, Luis Ferreira Moita
Publikováno v:
eLife, Vol 11 (2022)
Anthracyclines are among the most used and effective anticancer drugs. Their activity has been attributed to DNA double-strand breaks resulting from topoisomerase II poisoning and to eviction of histones from select sites in the genome. Here, we show
Externí odkaz:
https://doaj.org/article/32ef11be914c4b2e932acba420ab64bc
Autor:
Franziska Schöneweck, Roland P. H. Schmitz, Florian Rißner, André Scherag, Bettina Löffler, Mathias W. Pletz, Sebastian Weis, Frank M. Brunkhorst, Stefan Hagel
Publikováno v:
Antimicrobial Resistance and Infection Control, Vol 10, Iss 1, Pp 1-9 (2021)
Abstract Background Monitoring pathogens of bloodstream infections (BSI) and their antibiotic susceptibility is important to guide empiric antibiotic treatment strategies and prevention programs. This study assessed the epidemiology of BSI and antibi
Externí odkaz:
https://doaj.org/article/253796cf50f44dd78a758e672ec33c19
Autor:
Wolfgang Vivas, Sebastian Weis
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Pathogens, their toxic byproducts, and the subsequent immune reaction exert different forms of stress and damage to the tissue of the infected host. This stress can trigger specific transcriptional and post-transcriptional programs that have evolved
Externí odkaz:
https://doaj.org/article/1f8aef01ad9d4a95b20f55a2ae1d08f3
Autor:
Gloria Asantewaa, Nsoh Godwin Anabire, Michael Bauer, Sebastian Weis, Sophie Neugebauer, Osbourne Quaye, Gideon Kofi Helegbe
Publikováno v:
Diseases, Vol 11, Iss 3, p 94 (2023)
Plasmodium falciparum (P. falciparum) and hepatitis B virus (HBV) co-infection is on the rise among pregnant women in northern Ghana. Mono-infection with either of these two pathogens results in unique metabolic alterations. Thus, we aimed to explica
Externí odkaz:
https://doaj.org/article/07e4c9290f0d40efbdc11f48e1c6046f