Výsledky vyhledávání - "Sebastian Weißmann"

Akademický článek

Mucosal Heterologous Prime/Boost Vaccination Induces Polyfunctional Systemic Immunity, Improving Protection Against Trypanosoma cruzi

Autor: Andrés Sanchez Alberti, Augusto E. Bivona, Marina N. Matos, Natacha Cerny, Kai Schulze, Sebastian Weißmann, Thomas Ebensen, Germán González, Celina Morales, Alejandro C. Cardoso, Silvia I. Cazorla, Carlos A. Guzmán, Emilio L. Malchiodi

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

There are several unmet needs in modern immunology. Among them, vaccines against parasitic diseases and chronic infections lead. Trypanosoma cruzi, the causative agent of Chagas disease, is an excellent example of a silent parasitic invasion that aff

Externí odkaz: https://doaj.org/article/aa1c1391ec164399ad442f6f225b17b7

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Akademický článek

Engineered trivalent immunogen adjuvanted with a STING agonist confers protection against Trypanosoma cruzi infection

Autor: Andrés Sanchez Alberti, Augusto E. Bivona, Natacha Cerny, Kai Schulze, Sebastian Weißmann, Thomas Ebensen, Celina Morales, Angel M. Padilla, Silvia I. Cazorla, Rick L. Tarleton, Carlos A. Guzmán, Emilio L. Malchiodi

Publikováno v: npj Vaccines, Vol 2, Iss 1, Pp 1-12 (2017)

Chagas disease: protecting from chronic parasitic disease An amalgamation of parasitic proteins may be the first effective vaccine against the as yet untreatable chronic phase of Chagas disease. The infliction, caused by the parasite Trypanosoma cruz

Externí odkaz: https://doaj.org/article/ae1f0273188b48babe69f8e20ee1e766

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Akademický článek

Mucosal Administration of Cycle-Di-Nucleotide-Adjuvanted Virosomes Efficiently Induces Protection against Influenza H5N1 in Mice

Autor: Thomas Ebensen, Jennifer Debarry, Gabriel K. Pedersen, Paulina Blazejewska, Sebastian Weissmann, Kai Schulze, Kenneth C. McCullough, Rebecca J. Cox, Carlos A. Guzmán

Publikováno v: Frontiers in Immunology, Vol 8 (2017)

The need for more effective influenza vaccines is highlighted by the emergence of novel influenza strains, which can lead to new pandemics. There is a growing population of susceptible subjects at risk for severe complications of influenza, such as t

Externí odkaz: https://doaj.org/article/823265d357f44f59aa1a3b2f3b294ace

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Akademický článek

Gene Expression Driven by a Strong Viral Promoter in MVA Increases Vaccination Efficiency by Enhancing Antibody Responses and Unmasking CD8+ T Cell Epitopes

Autor: Pablo D. Becker, Miriam Nörder, Sebastian Weissmann, Ronny Ljapoci, Volker Erfle, Ingo Drexler, Carlos A. Guzmán

Publikováno v: Vaccines, Vol 2, Iss 3, Pp 581-600 (2014)

Viral vectors are promising tools for vaccination strategies and immunotherapies. However, CD8+ T cell responses against pathogen-derived epitopes are usually limited to dominant epitopes and antibody responses to recombinant encoded antigens (Ags) a

Externí odkaz: https://doaj.org/article/37e12351467c4479914bf6394856f969

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Cyclic Di-Adenosine Monophosphate: A Promising Adjuvant Candidate for the Development of Neonatal Vaccines

Autor: Carlos A. Guzmán, Darío Lirussi, Sebastian Weissmann, Ursula Nitsche-Gloy, Heiko B. G. Franz, Thomas Ebensen

Publikováno v: Pharmaceutics
Switzerland
Pharmaceutics, Vol 13, Iss 188, p 188 (2021)
Volume 13
Issue 2

Underdeveloped immunity during the neonatal age makes this period one of the most dangerous during the human lifespan, with infection-related mortality being one of the highest of all age groups. It is also discussed that vaccination during this time

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6871a5e38a4a4ee0d4a402937b3c1ef3
http://europepmc.org/articles/PMC7912751

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Mucosal Heterologous Prime/Boost Vaccination Induces Polyfunctional Systemic Immunity, Improving Protection Against

Publikováno v: Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb010de1158b8e3aa8898593996f176
https://pubmed.ncbi.nlm.nih.gov/32153562

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Gene Expression Driven by a Strong Viral Promoter in MVA Increases Vaccination Efficiency by Enhancing Antibody Responses and Unmasking CD8+ T Cell Epitope

Autor: Volker Erfle, Ronny Ljapoci, Pablo D. Becker, Carlos A. Guzmán, Ingo Drexler, Sebastian Weissmann, Miriam Nörder

Publikováno v: Vaccines
Vaccines, Vol 2, Iss 3, Pp 581-600 (2014)
Vaccines; Volume 2; Issue 3; Pages: 581-600
Vaccines 2, 581-600 (2015)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee578e2bd3bd12fdef857dba07755416
http://europepmc.org/articles/PMC4494220

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Non-invasive delivery of nanoparticles to hair follicles: A perspective for transcutaneous immunization

Autor: Claus-Michael Lehr, Thomas Ebensen, Kai Schulze, Ankit Mittal, Ulrich F. Schaefer, Anne S. Raber, Steffi Hansen, Sebastian Weissmann, Carlos A. Guzmán

Publikováno v: Vaccine. 31:3442-3451

Transfollicular vaccination aims to reach the peri-follicular antigen presenting cells without impairing the stratum corneum (SC) barrier. This would be an optimal vaccination strategy under critical hygienic conditions. Nanoparticles (NPs) are the i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6f068b60ab4ecbd40ac5f0abb43612
https://doi.org/10.1016/j.vaccine.2012.12.048

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Engineered trivalent immunogen adjuvanted with a STING agonist confers protection against

Autor: Andrés, Sanchez Alberti, Augusto E, Bivona, Natacha, Cerny, Kai, Schulze, Sebastian, Weißmann, Thomas, Ebensen, Celina, Morales, Angel M, Padilla, Silvia I, Cazorla, Rick L, Tarleton, Carlos A, Guzmán, Emilio L, Malchiodi

Publikováno v: NPJ Vaccines

The parasite Trypanosoma cruzi is the causative agent of Chagas disease, a potentially life-threatening infection that represents a major health problem in Latin America. Several characteristics of this protozoan contribute to the lack of an effectiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6c0c815d43a8d57ad60e42614edcdf5f
https://pubmed.ncbi.nlm.nih.gov/29263868

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