Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sebastian Unic"'
Autor:
Mariela Cortés-López, Laura Schulz, Mihaela Enculescu, Claudia Paret, Bea Spiekermann, Mathieu Quesnel-Vallières, Manuel Torres-Diz, Sebastian Unic, Anke Busch, Anna Orekhova, Monika Kuban, Mikhail Mesitov, Miriam M. Mulorz, Rawan Shraim, Fridolin Kielisch, Jörg Faber, Yoseph Barash, Andrei Thomas-Tikhonenko, Kathi Zarnack, Stefan Legewie, Julian König
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Multiple alternative splicing events in CD19 mRNA have been associated with resistance/relapse to CD19 CAR-T therapy in patients with B cell malignancies. Here, by combining patient data and a high-throughput mutagenesis screen, the authors identify
Externí odkaz:
https://doaj.org/article/c08d347a8dc943b8ab905da6ad76b36d
Autor:
Mariela, Cortés-López, Laura, Schulz, Mihaela, Enculescu, Claudia, Paret, Bea, Spiekermann, Mathieu, Quesnel-Vallières, Manuel, Torres-Diz, Sebastian, Unic, Anke, Busch, Anna, Orekhova, Monika, Kuban, Mikhail, Mesitov, Miriam M, Mulorz, Rawan, Shraim, Fridolin, Kielisch, Jörg, Faber, Yoseph, Barash, Andrei, Thomas-Tikhonenko, Kathi, Zarnack, Stefan, Legewie, Julian, König
Publikováno v:
Nature communications. 13(1)
Following CART-19 immunotherapy for B-cell acute lymphoblastic leukaemia (B-ALL), many patients relapse due to loss of the cognate CD19 epitope. Since epitope loss can be caused by aberrant CD19 exon 2 processing, we herein investigate the regulatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3adc23a1f7e72bbc70f381f619ca75e5
https://pubmed.ncbi.nlm.nih.gov/36138008
https://pubmed.ncbi.nlm.nih.gov/36138008