Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Sebastian T, Balbach"'
Autor:
Anja Fischer, Thomas K. Albert, Natalia Moreno, Marta Interlandi, Jana Mormann, Selina Glaser, Paurnima Patil, Flavia W. de Faria, Mathis Richter, Archana Verma, Sebastian T. Balbach, Rabea Wagener, Susanne Bens, Sonja Dahlum, Carolin Göbel, Daniel Münter, Clara Inserte, Monika Graf, Eva Kremer, Viktoria Melcher, Gioia Di Stefano, Raffaella Santi, Alexander Chan, Ahmet Dogan, Jonathan Bush, Martin Hasselblatt, Sylvia Cheng, Signe Spetalen, Alexander Fosså, Wolfgang Hartmann, Heidi Herbrüggen, Stella Robert, Florian Oyen, Martin Dugas, Carolin Walter, Sarah Sandmann, Julian Varghese, Claudia Rossig, Ulrich Schüller, Alexandar Tzankov, Martin B. Pedersen, Francesco A. d’Amore, Karin Mellgren, Udo Kontny, Venkatesh Kancherla, Luis Veloza, Edoardo Missiaglia, Virginie Fataccioli, Philippe Gaulard, Birgit Burkhardt, Oliver Soehnlein, Wolfram Klapper, Laurence de Leval, Reiner Siebert, Kornelius Kerl
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Peripheral T-cell lymphoma, not otherwise specified (PTCL-NOS) is a heterogeneous group of malignancies with poor outcome. Here, we identify a subgroup, PTCL-NOS SMARCB1- , which is characterized by the lack of the SMARCB1 protein and occurs
Externí odkaz:
https://doaj.org/article/f9838f5a5f15480799585f8fa2420a7e
Autor:
Pethő, Sebastian Fuest, Christoph Post, Sebastian T. Balbach, Susanne Jabar, Ilka Neumann, Sandra Schimmelpfennig, Sarah Sargin, Elke Nass, Thomas Budde, Sareetha Kailayangiri, Bianca Altvater, Andreas Ranft, Wolfgang Hartmann, Uta Dirksen, Claudia Rössig, Albrecht Schwab, Zoltán
Publikováno v:
Cancers; Volume 14; Issue 19; Pages: 4819
Ewing sarcoma (EwS) is a rare and highly malignant bone tumor occurring mainly in childhood and adolescence. Physiologically, the bone is a central hub for Ca2+ homeostasis, which is severely disturbed by osteolytic processes in EwS. Therefore, we ai
Autor:
Sebastian, Fuest, Christoph, Post, Sebastian T, Balbach, Susanne, Jabar, Ilka, Neumann, Sandra, Schimmelpfennig, Sarah, Sargin, Elke, Nass, Thomas, Budde, Sareetha, Kailayangiri, Bianca, Altvater, Andreas, Ranft, Wolfgang, Hartmann, Uta, Dirksen, Claudia, Rössig, Albrecht, Schwab, Zoltán, Pethő
Publikováno v:
Cancers. 14(19)
Ewing sarcoma (EwS) is a rare and highly malignant bone tumor occurring mainly in childhood and adolescence. Physiologically, the bone is a central hub for Ca
Autor:
Telma C Esteves, Olympia E Psathaki, Martin J Pfeiffer, Sebastian T Balbach, Dagmar Zeuschner, Hiroshi Shitara, Hiromichi Yonekawa, Marcin Siatkowski, Georg Fuellen, Michele Boiani
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e36850 (2012)
While reprogramming a foreign nucleus after somatic cell nuclear transfer (SCNT), the enucleated oocyte (ooplasm) must signal that biomass and cellular requirements changed compared to the nucleus donor cell. Using cells expressing nuclear-encoded bu
Externí odkaz:
https://doaj.org/article/1de266845ed8472d9e9f4096f307d6da
Autor:
Melissa A. Burns, Pieter Van Vlierberghe, Lewis B. Silverman, Karen R. Rabin, Donna Neuberg, Kimberly Bodaar, Randi Isenhart, Salmaan Karim, Birgit Knoechel, Meenakshi Devidas, Stuart H. Orkin, Björn Menten, Alejandro Gutierrez, Triona Ni Chonghaile, James Degar, Kristen E. Stevenson, Ingrid M. Ariës, Kimberly P. Dunsmore, Sofie Peirs, Sebastian T. Balbach, Jack T Landrigan, Stephen E. Sallan, Mignon L. Loh, Laura Hinze, Anthony Letai, Maren Pfirrmann, Brent L. Wood, David T. Teachey, Stuart S. Winter, Stephen P. Hunger
Publikováno v:
The Journal of Experimental Medicine
JOURNAL OF EXPERIMENTAL MEDICINE
The Journal of experimental medicine, vol 215, iss 12
JOURNAL OF EXPERIMENTAL MEDICINE
The Journal of experimental medicine, vol 215, iss 12
Mitochondrial apoptotic priming predicts response to cancer chemotherapy, but the mechanisms underlying variability in this mitochondrial phenotype among closely related tumors are poorly understood. Ariës et al. show that PRC2 loss-of-function muta
Autor:
Holger N. Lode, Nikolai Siebert, Claudia Rossig, Kornelius Kerl, Ingo Müller, Claudia Göttlich, Stefanie Lesch, Bianca Altvater, Maike Fluegge, Wolfgang Hartmann, Sonja Schelhaas, Silke Jamitzky, Sebastian T. Balbach, Lea Greune, Heike Walles, Johanna Kühnemundt, Jutta Meltzer, Sareetha Kailayangiri, Jan-Henrik Mikesch, Nicole Farwick
Publikováno v:
Mol Ther
Chimeric antigen receptor (CAR) engineering of T cells allows one to specifically target tumor cells via cell surface antigens. A candidate target in Ewing sarcoma is the ganglioside G(D2), but heterogeneic expression limits its value. Here we report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1c54360ba8e25b4d1bfedff824acf87
https://europepmc.org/articles/PMC6520468/
https://europepmc.org/articles/PMC6520468/
Autor:
Olga Makarova, Sebastian T. Balbach, Bettina R. Bonn, Claudia Rossig, Martin Zimmermann, Ilske Oschlies, Birgit Burkhardt, Wolfram Klapper, Marius Rohde
Publikováno v:
Leukemia. 30:970-973
T-cell lymphoblastic lymphoma (T-LBL) represents the second most common subtype of non-Hodgkin’s lymphoma (NHL) in children and adolescents. Current chemotherapy protocols reach event-free survival probabilities (pEFS) of 75–85%,1 and are associa
Autor:
Sebastian T. Balbach, Michele Boiani, Caroline Schwarzer, Anna Jauch, Franchesca D. Houghton, Martin Stehling, Marcos J. Araúzo-Bravo, Martin J. Pfeiffer, Telma C. Esteves
Publikováno v:
Stem Cells. 31:2343-2353
The conversion of the nuclear program of a somatic cell from a differentiated to an undifferentiated state can be accomplished by transplanting its nucleus to an enucleated oocyte (somatic cell nuclear transfer [SCNT]) in a process termed “reprogra
Autor:
Sebastian T. Balbach, Stuart H. Orkin
Publikováno v:
Cancer discovery. 6(7)
Numerous studies in multiple systems support that histone H3 lysine 36 di-methylation (H3K36me2) is associated with transcriptional activation, however the underlying mechanisms are not well defined. Here we show that the H3K36me2 chromatin mark writ
Autor:
Telma C. Esteves, Sebastian T. Balbach, Michele Boiani, Martina Sinn, Martin J. Pfeiffer, Marcos J. Araúzo-Bravo, Diana C. Klein
Publikováno v:
Aging Cell. 10:80-95
The mammalian oocyte has the unique feature of supporting fertilization and normal development, while capable of reprogramming nuclei of somatic cells toward pluripotency, and occasionally even totipotency. While oocyte quality is known to decay with