Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Sebastian Sorge"'
Autor:
Aleksandra Lubojemska, M Irina Stefana, Sebastian Sorge, Andrew P Bailey, Lena Lampe, Azumi Yoshimura, Alana Burrell, Lucy Collinson, Alex P Gould
Publikováno v:
PLoS Biology, Vol 19, Iss 5, p e3001230 (2021)
Obesity-related renal lipotoxicity and chronic kidney disease (CKD) are prevalent pathologies with complex aetiologies. One hallmark of renal lipotoxicity is the ectopic accumulation of lipid droplets in kidney podocytes and in proximal tubule cells.
Externí odkaz:
https://doaj.org/article/c2420fbbe44c4971ad94c300bacf35a2
Autor:
Masanari Takamiya, Johannes Stegmaier, Andrei Yu Kobitski, Benjamin Schott, Benjamin D Weger, Dimitra Margariti, Angel R Cereceda Delgado, Victor Gourain, Tim Scherr, Lixin Yang, Sebastian Sorge, Jens C Otte, Volker Hartmann, Jos van Wezel, Rainer Stotzka, Thomas Reinhard, Günther Schlunck, Thomas Dickmeis, Sepand Rastegar, Ralf Mikut, Gerd Ulrich Nienhaus, Uwe Strähle
Publikováno v:
PLoS Genetics, Vol 16, Iss 6, p e1008774 (2020)
Cranial neural crest (NC) contributes to the developing vertebrate eye. By multidimensional, quantitative imaging, we traced the origin of the ocular NC cells to two distinct NC populations that differ in the maintenance of sox10 expression, Wnt sign
Externí odkaz:
https://doaj.org/article/8e4da45e746442678c656ac1c39e9a74
Autor:
Sebastian Sorge, Jonas Theelke, Kerem Yildirim, Helen Hertenstein, Ellen McMullen, Stephan Müller, Christian Altbürger, Stefanie Schirmeier, Ingrid Lohmann
Publikováno v:
Cell Reports, Vol 31, Iss 7, Pp - (2020)
Summary: The mitochondrial electron transport chain (ETC) enables essential metabolic reactions; nonetheless, the cellular responses to defects in mitochondria and the modulation of signaling pathway outputs are not understood. We show that Notch sig
Externí odkaz:
https://doaj.org/article/1441f278caa34f1eb6911a53bb7a25a4
Autor:
Jana Friedrich, Sebastian Sorge, Fatmire Bujupi, Michael P. Eichenlaub, Natalie G. Schulz, Jochen Wittbrodt, Ingrid Lohmann
Publikováno v:
Cell Reports, Vol 14, Iss 4, Pp 850-860 (2016)
Feeding is an evolutionarily conserved and integral behavior that depends on the rhythmic activity of feeding muscles stimulated by specific motoneurons. However, critical molecular determinants underlying the development of the neuromuscular feeding
Externí odkaz:
https://doaj.org/article/ad632dea209b43bfb91efb49991dbe5a
Autor:
Zongzhao Zhai, Nati Ha, Fani Papagiannouli, Anne Hamacher-Brady, Nathan Brady, Sebastian Sorge, Daniela Bezdan, Ingrid Lohmann
Publikováno v:
PLoS Genetics, Vol 8, Iss 3, p e1002582 (2012)
Apoptosis is essential to prevent oncogenic transformation by triggering self-destruction of harmful cells, including those unable to differentiate. However, the mechanisms linking impaired cell differentiation and apoptosis during development and di
Externí odkaz:
https://doaj.org/article/39522d74920f46fa96f1506ded77a9a7
Autor:
Stephan Müller, Ingrid Lohmann, Ellen McMullen, Helen Hertenstein, Christian Altburger, Kerem Yildirim, Stefanie Schirmeier, Jonas Theelke, Sebastian Sorge
Publikováno v:
Cell Reports, Vol 31, Iss 7, Pp-(2020)
Summary: The mitochondrial electron transport chain (ETC) enables essential metabolic reactions; nonetheless, the cellular responses to defects in mitochondria and the modulation of signaling pathway outputs are not understood. We show that Notch sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::527c0ba53d86e7b11981d28614300e78
https://pubmed.ncbi.nlm.nih.gov/32433968
https://pubmed.ncbi.nlm.nih.gov/32433968
Autor:
Lena Lampe, Alana Burrell, Sebastian Sorge, Lucy M. Collinson, Andrew P. Bailey, M. Irina Stefana, Alex P. Gould, Aleksandra Lubojemska, Azumi Yoshimura
Publikováno v:
PLoS Biology, Vol 19, Iss 5, p e3001230 (2021)
PLoS Biology
PLoS Biology
Obesity-related renal lipotoxicity and chronic kidney disease (CKD) are prevalent pathologies with complex aetiologies. One hallmark of renal lipotoxicity is the ectopic accumulation of lipid droplets in kidney podocytes and in proximal tubule cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1643a7c1334b17b0bb761659fdb291b8
https://doi.org/10.1371/journal.pbio.3001230
https://doi.org/10.1371/journal.pbio.3001230
Autor:
Ingrid Lohmann, Jana Friedrich, Natalie G. Schulz, Michael P. Eichenlaub, Fatmire Bujupi, Jochen Wittbrodt, Sebastian Sorge
Publikováno v:
Cell Reports, Vol 14, Iss 4, Pp 850-860 (2016)
SummaryFeeding is an evolutionarily conserved and integral behavior that depends on the rhythmic activity of feeding muscles stimulated by specific motoneurons. However, critical molecular determinants underlying the development of the neuromuscular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cf11fd6ac1e03e1d198acdd393ac4a0
http://www.sciencedirect.com/science/article/pii/S2211124715015338
http://www.sciencedirect.com/science/article/pii/S2211124715015338
The mitochondrial electron transport chain (ETC) enables many important metabolic reactions, like ATP generation and redox balance. While the vital importance of mitochondrial function is obvious, the cellular response to defects in mitochondria and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a863653dab7c0c0d5678e1546e8dd81f
Autor:
Jenny Rätzer, Fani Papagiannouli, Jana Friedrich, Martin Schaefer, Stephan Ossowski, Stefan R. Henz, Maria Polychronidou, Sebastian Sorge, Petra Kaspar, Daniela Bezdan, Juliane Mundorf, Nati Ha, Ingrid Lohmann
Publikováno v:
The EMBO Journal. 31:3323-3333
Precise gene expression is a fundamental aspect of organismal function and depends on the combinatorial interplay of transcription factors (TFs) with cis-regulatory DNA elements. While much is known about TF function in general, our understanding of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::caee818d188175db35af4c7567782899
https://doi.org/10.1038/emboj.2012.179
https://doi.org/10.1038/emboj.2012.179