Zobrazeno 1 - 10
of 662
pro vyhledávání: '"Sebastian Schneeweiss"'
Publikováno v:
BMJ Medicine, Vol 3, Iss 1 (2024)
Objective To explore how design emulation and population differences relate to variation in results between randomised controlled trials (RCT) and non-randomised real world evidence (RWE) studies, based on the RCT-DUPLICATE initiative (Randomised, Co
Externí odkaz:
https://doaj.org/article/9e3119892f264705bccfe5525e3af4e3
Autor:
Benjamin Ackerman, Ryan W. Gan, Craig S. Meyer, Jocelyn R. Wang, Youyi Zhang, Jennifer Hayden, Grace Mahoney, Jennifer L. Lund, Janick Weberpals, Sebastian Schneeweiss, James Roose, Juned Siddique, Omar Nadeem, Smith Giri, Til Stürmer, Sikander Ailawadhi, Ashita S. Batavia, Khaled Sarsour
Publikováno v:
Frontiers in Drug Safety and Regulation, Vol 4 (2024)
Introduction: While randomized controlled trials remain the reference standard for evaluating treatment efficacy, there is an increased interest in the use of external control arms (ECA), namely in oncology, using real-world data (RWD). Challenges re
Externí odkaz:
https://doaj.org/article/c00455226d6749b884e3043112d1c680
Autor:
Phyo T. Htoo, Helen Tesfaye, Sebastian Schneeweiss, Deborah J. Wexler, Brendan M. Everett, Robert J. Glynn, Niklas Schmedt, Lisette Koeneman, Anouk Déruaz-Luyet, Julie M. Paik, Elisabetta Patorno
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background No randomized clinical trials have directly compared the cardiorenal effectiveness of empagliflozin and GLP-1RA agents with demonstrated cardioprotective effects in patients with a broad spectrum of cardiovascular risk. We reporte
Externí odkaz:
https://doaj.org/article/a409dae7b8d64bffbc67fb3a8cee406b
Autor:
Maria Kahn, Steffeni Papukchieva, Elizabeth Jacyshyn-Owen, Stefan Grimm, Markus Eberl, Sebastian Schneeweiss, Marina Otten, Matthias Augustin, Benjamin Friedrich
Publikováno v:
Dermatology and Therapy, Vol 13, Iss 11, Pp 2609-2620 (2023)
Abstract Introduction Real-world evidence (RWE) data is increasingly important to generate rapid insights to effectively manage patient populations. Disruptions like the coronavirus disease 2019 (COVID-19) pandemic may negatively impact the choice of
Externí odkaz:
https://doaj.org/article/aaeb553c9928475c90d93d52e7e43eb7
Autor:
Phyo T. Htoo, Helen Tesfaye, Sebastian Schneeweiss, Deborah J. Wexler, Brendan M. Everett, Robert J. Glynn, Niklas Schmedt, Lisette Koeneman, Anouk Déruaz-Luyet, Julie M. Paik, Elisabetta Patorno
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-2 (2024)
Externí odkaz:
https://doaj.org/article/1b45064e466d4e25abc84ea3e931b788
Publikováno v:
JID Innovations, Vol 3, Iss 6, Pp 100226- (2023)
The U.S. Food and Drug Administration and clinical guidelines use evidence from pharmacoepidemiology studies to inform prescribing decisions and fill evidence gaps left by randomized controlled trials (RCTs). The long-term safety and infrequent adver
Externí odkaz:
https://doaj.org/article/723e368cba2e4256aeccdc344bfd5be4
Autor:
Sallie-Anne Pearson, Sebastian Schneeweiss, James H McAuley, Jonathan Sterne, Elizabeth A Stuart, Miguel A Hernán, Hopin Lee, Sonja A Swanson, Matthias Egger, Melissa K Sharp, Aidan G Cashin, Nazrul Islam, Matthew D Jones, Issa J Dahabreh, Sara Lodi, Robert M Golub, Harrison J Hansford, Margarita Moreno-Betancur, Barbra A Dickerman, Xavier Garcia-Albeniz
Publikováno v:
BMJ Open, Vol 13, Iss 9 (2023)
Background Observational studies are increasingly used to inform health decision-making when randomised trials are not feasible, ethical or timely. The target trial approach provides a framework to help minimise common biases in observational studies
Externí odkaz:
https://doaj.org/article/9ef23453032642578ebd52e6199ac2c9
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
Analyses of real-world evidence from digital clinical practice data provide important insights for healthcare decision makers. Here, authors test reproducibility of 150 peer-reviewed studies, reporting strong reproducibility, which could be further i
Externí odkaz:
https://doaj.org/article/0806d1a4c41d4cbf939f42f298fa3ae3
Autor:
Tracey G. Simon, Sebastian Schneeweiss, Daniel E. Singer, Sushama Kattinakere Sreedhara, Kueiyu Joshua Lin
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 3 (2023)
Background Many patients with cirrhosis have concurrent nonvalvular atrial fibrillation (NVAF). Data are lacking regarding recent oral anticoagulant (OAC) usage trends among US patients with cirrhosis and NVAF. Methods and Results Using MarketScan cl
Externí odkaz:
https://doaj.org/article/d888ad400d844d35b12da7817270caa6
Autor:
Jonathan Orschiedt, Elizabeth Jacyshyn-Owen, Maria Kahn, Sven Jansen, Natalie Joschko, Markus Eberl, Sebastian Schneeweiss, Benjamin Friedrich, Tjalf Ziemssen
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 158, Iss , Pp 114129- (2023)
Background: Real-word evidence from diverse data sources is increasingly important in terms of generating rapid insights to effectively manage patient populations, especially during major public health disruptions such as the ongoing COVID-19 pandemi
Externí odkaz:
https://doaj.org/article/119c7a10e18e495988429747ae78794b