Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sebastian Sakowski"'
Autor:
Grzegorz Dudek, Sebastian Sakowski, Olga Brzezińska, Joanna Sarnik, Tomasz Budlewski, Grzegorz Dragan, Marta Poplawska, Tomasz Poplawski, Michał Bijak, Joanna Makowska
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0300717 (2024)
Machine learning (ML) algorithms can handle complex genomic data and identify predictive patterns that may not be apparent through traditional statistical methods. They become popular tools for medical applications including prediction, diagnosis or
Externí odkaz:
https://doaj.org/article/cacca4404d51460ea692419b62c432a3
Autor:
Grzegorz Galita, Joanna Sarnik, Olga Brzezinska, Tomasz Budlewski, Marta Poplawska, Sebastian Sakowski, Grzegorz Dudek, Ireneusz Majsterek, Joanna Makowska, Tomasz Poplawski
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2619 (2024)
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation affecting up to 2.0% of adults around the world. The molecular background of RA has not yet been fully elucidated, but RA is classified as a disease in which the
Externí odkaz:
https://doaj.org/article/a9c9ee6f333f4796b520fc672da98ccd
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 5, p 4681 (2023)
The increasingly expanding genomic databases generate the need for new tools for their processing and further use. In the paper, a bioinformatics tool, which is a search engine of microsatellite elements—trinucleotide repeat sequences (TRS) in file
Externí odkaz:
https://doaj.org/article/be5796bd3f0e47f5974e4760a757bf65
Publikováno v:
Applied Sciences, Vol 12, Iss 14, p 6928 (2022)
The branch of informatics that deals with construction and operation of computers built of DNA, is one of the research directions which investigates issues related to the use of DNA as hardware and software. This concept assumes the use of DNA comput
Externí odkaz:
https://doaj.org/article/4755b5a88bc74521981d41a29404b789
Autor:
Krzysztof Bartoszek, Marta Majchrzak, Sebastian Sakowski, Anna B Kubiak-Szeligowska, Ingemar Kaj, Pawel Parniewski
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 1, p e1005931 (2018)
The Binary State Speciation and Extinction (BiSSE) model is a branching process based model that allows the diversification rates to be controlled by a binary trait. We develop a general approach, based on the BiSSE model, for predicting pathogenicit
Externí odkaz:
https://doaj.org/article/f95e593ba0eb469e888b96440638b98d
Autor:
Sebastian Sakowski, Tadeusz Krasinski, Jacek Waldmajer, Joanna Sarnik, Janusz Blasiak, Tomasz Poplawski
Publikováno v:
Genetics and Molecular Biology, Iss 0 (2017)
Abstract The development of conventional, silicon-based computers has several limitations, including some related to the Heisenberg uncertainty principle and the von Neumann “bottleneck”. Biomolecular computers based on DNA and proteins are large
Externí odkaz:
https://doaj.org/article/67f28f9631a24f629e2b6f3b9f0f3663
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 5
Pages: 4681
Volume 24
Issue 5
Pages: 4681
The increasingly expanding genomic databases generate the need for new tools for their processing and further use. In the paper, a bioinformatics tool, which is a search engine of microsatellite elements—trinucleotide repeat sequences (TRS) in file
Publikováno v:
Computational Intelligence Methods for Bioinformatics and Biostatistics ISBN: 9783031208362
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9337f369fb3dfd42bbfc344d70eb1622
https://doi.org/10.1007/978-3-031-20837-9_14
https://doi.org/10.1007/978-3-031-20837-9_14
Publikováno v:
Theoretical Computer Science. 785:60-82
In the paper, a fragment of the new theory of tailor automata is presented, within which a deterministic finite automaton was defined. The proposed automaton provides a theoretical model of an informally characterized biomolecular automaton. The idea
Autor:
Sebastian Sakowski, Jacek Waldmajer
Publikováno v:
Informatica. 43
The authors present a solution to the problem of generating the maximum possible number of symbols for a biomolecular computer using restriction enzyme BbvI and ligase as the hardware, and transition molecules built of double-stranded DNA as the soft