Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Sebastian Rausch"'
Autor:
Luis E. Elizalde-Velázquez, Josephine Schlosser-Brandenburg, Alexandra Laubschat, Larissa Oser, Arkadi Kundik, Joshua Adjah, Saskia Groenhagen, Anja A. Kühl, Sebastian Rausch, Susanne Hartmann
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Helminth infections lead to an overdispersion of the parasites in humans as well as in animals. We asked whether early immune responses against migrating Ascaris larvae are responsible for the unequal distribution of worms in natural host po
Externí odkaz:
https://doaj.org/article/0fad04632c68456fbf362cbca7a4dcdc
Autor:
Robert M. Mugo, Larissa Oser, Ankur Midha, Joshua Adjah, Arkadi Kundik, Alexandra Laubschat, Philipp Höfler, Zaneta D. Musimbi, Rima Hayani, Josephine Schlosser-Brandenburg, Susanne Hartmann, Sebastian Rausch
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Natural killer (NK) cells play a key role in defense against Salmonella infections during the early phase of infection. Our previous work showed that the excretory/secretory products of Ascaris suum repressed NK activity in vitro. Here, we a
Externí odkaz:
https://doaj.org/article/3179835dfd614f148a2a73389efd8278
Autor:
Ankur Midha, Larissa Oser, Josephine Schlosser-Brandenburg, Alexandra Laubschat, Robert M. Mugo, Zaneta D. Musimbi, Philipp Höfler, Arkadi Kundik, Rima Hayani, Joshua Adjah, Saskia Groenhagen, Malte Tieke, Luis E. Elizalde-Velázquez, Anja A. Kühl, Robert Klopfleisch, Karsten Tedin, Sebastian Rausch, Susanne Hartmann
Publikováno v:
mSphere, Vol 9, Iss 9 (2024)
ABSTRACT Ascaris is one of the most widespread helminth infections, leading to chronic morbidity in humans and considerable economic losses in pig farming. In addition, pigs are an important reservoir for the zoonotic salmonellosis, where pigs can se
Externí odkaz:
https://doaj.org/article/98244c79ce29447698b26323f2819a17
Autor:
Robert M Mugo, Sebastian Rausch, Zaneta D Musimbi, Christina Strube, Marie-Kristin Raulf, Olfert Landt, Paul M Gichuki, Friederike Ebner, Jedidah Mwacharo, Maurice R Odiere, Francis M Ndungu, Doris W Njomo, Susanne Hartmann
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 18, Iss 6, p e0012279 (2024)
BackgroundThe standard diagnosis of Ascaris lumbricoides and other soil-transmitted helminth (STH) infections relies on the detection of worm eggs by copromicroscopy. However, this method is dependent on worm patency and shows only limited accuracy i
Externí odkaz:
https://doaj.org/article/91077f3cc8424017a2d291e150ef0f27
Autor:
Larissa Oser, Ankur Midha, Josephine Schlosser-Brandenburg, Sebastian Rausch, Robert M. Mugo, Arkadi Kundik, Luis E. Elizalde-Velázquez, Joshua Adjah, Zaneta D. Musimbi, Robert Klopfleisch, Christina S. Helm, Georg von Samson-Himmelstjerna, Susanne Hartmann, Friederike Ebner
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Ascaris spp. undergo extensive migration within the body before establishing patent infections in the small intestinal tract of humans and pigs. However, whether larval migration is critical for inducing efficient type 2 responses remains poorly unde
Externí odkaz:
https://doaj.org/article/8008e6abf43b4c25a7d89954bd7bba19
Autor:
Wjatscheslaw Liublin, Sebastian Rausch, Ruth Leben, Randall L. Lindquist, Alexander Fiedler, Juliane Liebeskind, Ingeborg E. Beckers, Anja E. Hauser, Susanne Hartmann, Raluca A. Niesner
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Infections with intestinal nematodes have an equivocal impact: they represent a burden for human health and animal husbandry, but, at the same time, may ameliorate auto-immune diseases due to the immunomodulatory effect of the parasites. Thu
Externí odkaz:
https://doaj.org/article/8e52b3b3e61a47e59b7d4c641fbe7def
Autor:
Benjamin Hamid, Friederike Ebner, Lalita Bechtold, Arkadi Kundik, Sebastian Rausch, Susanne Hartmann
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Helminths produce excretory/secretory products (E/S) which can modulate the immune responses of their hosts. Dendritic cells (DC) are essential for initiating the host T cell response and are thus potential targets for modulation by helminth E/S. Her
Externí odkaz:
https://doaj.org/article/ba9ab82d66084de0b0ab3431c9b7f6c2
Autor:
Jörn Lewin, Denise Kottwitz, Johanna Aoyama, Theo deVos, Jorge Garces, Oliver Hasinger, Stefanie Kasielke, Florian Knaust, Preeti Rathi, Sebastian Rausch, Gunter Weiss, Alexander Zipprich, Edward Mena, Tse-Ling Fong
Publikováno v:
BMC Gastroenterology, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Background Hepatocellular carcinoma (HCC) is the leading cause of death in patients with cirrhosis, primarily due to failed early detection. HCC screening is recommended among individuals with cirrhosis using biannual abdominal ultrasound, f
Externí odkaz:
https://doaj.org/article/3d6ec220036e47cd95d5ef53bc9a5bcb
Publikováno v:
Swiss Journal of Economics and Statistics, Vol 155, Iss 1, Pp 1-18 (2019)
Abstract Collaborating under the Swiss Energy Modeling Platform (SEMP), five modeling teams (employing an energy systems model and four macroeconomic models with a focus on energy) have carried out a multi-model comparison to assess the economic and
Externí odkaz:
https://doaj.org/article/515bce7cc8094cbfa48b2e49aa3c806b
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-6 (2019)
Abstract Objective DNA methylation analysis via real-time PCR or other analytical techniques requires purified bisulfite converted DNA. We report on an automated high throughput solution for DNA extraction, bisulfite-conversion, and purification of 9
Externí odkaz:
https://doaj.org/article/0cbadf9ff1e24d69b0bcda81dfc2e4d8