Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sebastian Prill"'
Autor:
Piero Pingitore, Kavitha Sasidharan, Matias Ekstrand, Sebastian Prill, Daniel Lindén, Stefano Romeo
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 7, p 1629 (2019)
Non-alcoholic fatty liver disease (NAFLD) is the most common liver disorder in western countries. Despite the high prevalence of NAFLD, the underlying biology of the disease progression is not clear, and there are no approved drugs to treat non-alcoh
Externí odkaz:
https://doaj.org/article/4a764638cb624fed8d57ff1100105086
Autor:
Sebastian Prill
Publikováno v:
CITplus. 23:19-22
Autor:
Oveis Jamialahmadi, Annika Janefeldt, Carl Whatling, Luca Valenti, Mikael Kozyra, Kajsa P. Kanebratt, Tommy B. Andersson, Arturo Pujia, Paola Dongiovanni, Andrea Caddeo, Rosellina Margherita Mancina, Sebastian Prill, Magnus Ingelman-Sundberg, Stefano Romeo, Raffaela Rametta, Daniel Lindén, Guido Baselli, Piero Pingitore
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
There is a high unmet need for developing treatments for nonalcoholic fatty liver disease (NAFLD), for which there are no approved drugs today. Here, we used a human in vitro disease model to understand mechanisms linked to genetic risk variants asso
Autor:
Astrid Monecke, Arved Weimann, Justus Körfer, René Thieme, Volker Wiechmann, Anja Tennemann, Sebastian Prill, Christian Wittekind, Ines Gockel, Kerstin Grosser, Sonja Kallendrusch, Rasmus Sönnichsen, Ingo Bechmann, Florian Lordick, Jakob Rebstock, Orestis Lyros, Christoph Kubick
Publikováno v:
Oncotarget
Purpose: Presence of tumor-associated macrophages (TAM) and high levels of ferritin and lipocalin 2 (Lcn2) in the tumor microenvironment are associated with poor prognosis in many types of cancer. Here we investigate whether iron deprivation influenc
Autor:
Jose Tupac, Sebastian Prill
Publikováno v:
CITplus. 22:24-29
Publikováno v:
Drug Delivery and Translational Research. 8:1595-1603
Hot-melt extrusion on co-rotating twin screw extruders is a focused technology for the production of pharmaceuticals in the context of Quality by Design. Since it is a continuous process, the potential for minimizing product quality fluctuation is en
Autor:
Sebastian Prill, Martin Hübner, Matthias Voges, Christoph Held, I. V. Prikhod’ko, Gabriele Sadowski
Publikováno v:
Journal of Chemical & Engineering Data. 62:52-61
The solubility of the amino acids l-alanine and l-glutamic acid and its sodium salt (sodium l-glutamate monohydrate) in aqueous solutions at 30 °C and atmospheric pressure was investigated in the pH range between 3 and 9 and in the presence of the i
Autor:
Matias Ekstrand, Piero Pingitore, Stefano Romeo, Daniel Lindén, Sebastian Prill, Kavitha Sasidharan
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 20, Iss 7, p 1629 (2019)
Volume 20
Issue 7
International Journal of Molecular Sciences, Vol 20, Iss 7, p 1629 (2019)
Volume 20
Issue 7
Non-alcoholic fatty liver disease (NAFLD) is the most common liver disorder in western countries. Despite the high prevalence of NAFLD, the underlying biology of the disease progression is not clear, and there are no approved drugs to treat non-alcoh
Autor:
Elishai Ezra, Magnus S. Jaeger, Claus Duschl, Gahl Levy, Sebastian Prill, Danny Bavli, Michael Schwarz, Merav Cohen, Elmar Schmälzlin, Yaakov Nahmias
Publikováno v:
Archives of Toxicology. 90:1181-1191
Prediction of drug-induced toxicity is complicated by the failure of animal models to extrapolate human response, especially during assessment of repeated dose toxicity for cosmetic or chronic drug treatments. In this work, we present a 3D microreact
Autor:
Magnus S. Jaeger, Elishai Ezra, Danny Bavli, Gahl Levy, Yaakov Nahmias, Merav Cohen, Sebastian Prill, Jan Vanfleteren, Mathieu Vinken
Publikováno v:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Europe PubMed Central
Europe PubMed Central
Microfluidic organ-on-a-chip technology aims to replace animal toxicity testing, but thus far has demonstrated few advantages over traditional methods. Mitochondrial dysfunction plays a critical role in the development of chemical and pharmaceutical