Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Sebastian Patzke"'
Publikováno v:
Bio-Protocol, Vol 12, Iss 6 (2022)
The centrosome is the main microtubule-organizing center of animal cells, and is composed of two barrel-shaped microtubule-based centrioles embedded in protein dense pericentriolar material. Compositional and architectural re-organization of the cent
Externí odkaz:
https://doaj.org/article/4367f1ce57d649619ec080a95c85b0f4
Autor:
Marion M Malenge, Astri Fjelde Maaland, Ada Repetto-Llamazares, Brian Middleton, Marcel Nijland, Lydia Visser, Sebastian Patzke, Helen Heyerdahl, Arne Kolstad, Trond Stokke, Anne Hansen Ree, Jostein Dahle
Publikováno v:
PLoS ONE, Vol 17, Iss 4, p e0267543 (2022)
Background and purposePARP inhibitors have been shown to increase the efficacy of radiotherapy in preclinical models. Radioimmunotherapy results in selective radiation cytotoxicity of targeted tumour cells. Here we investigate the combined effect of
Externí odkaz:
https://doaj.org/article/0ff57784aa0f4af780996246d2a8a7e3
Autor:
André Brás Gonçalves, Sarah Kirstine Hasselbalch, Beinta Biskopstø Joensen, Sebastian Patzke, Pernille Martens, Signe Krogh Ohlsen, Mathieu Quinodoz, Konstantinos Nikopoulos, Reem Suleiman, Magnus Per Damsø Jeppesen, Catja Weiss, Søren Tvorup Christensen, Carlo Rivolta, Jens S Andersen, Pietro Farinelli, Lotte Bang Pedersen
Publikováno v:
eLife, Vol 10 (2021)
CEP78 is a centrosomal protein implicated in ciliogenesis and ciliary length control, and mutations in the CEP78 gene cause retinal cone-rod dystrophy associated with hearing loss. However, the mechanism by which CEP78 affects cilia formation is unkn
Externí odkaz:
https://doaj.org/article/4d5f5e4294184f34b50a9cda61e1c689
Autor:
Gro Elise Rødland, Katrine Melhus, Roman Generalov, Sania Gilani, Francesco Bertoni, Jostein Dahle, Randi G. Syljuåsen, Sebastian Patzke
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
The CD37 targeting radioimmunoconjugate 177Lu-lilotomab satetraxetan (Betalutin) is currently being evaluated in a clinical phase 2b trial for patients with follicular lymphoma (FL) and in a phase 1 trial for patients with diffuse large B-cell lympho
Externí odkaz:
https://doaj.org/article/f42a13b7d73f4b2e8332fd0c874cc7f7
Autor:
Kari-Anne M. Frikstad, Elisa Molinari, Marianne Thoresen, Simon A. Ramsbottom, Frances Hughes, Stef J.F. Letteboer, Sania Gilani, Kay O. Schink, Trond Stokke, Stefan Geimer, Lotte B. Pedersen, Rachel H. Giles, Anna Akhmanova, Ronald Roepman, John A. Sayer, Sebastian Patzke
Publikováno v:
Cell Reports, Vol 28, Iss 7, Pp 1907-1922.e6 (2019)
Summary: CEP104 is an evolutionarily conserved centrosomal and ciliary tip protein. CEP104 loss-of-function mutations are reported in patients with Joubert syndrome, but their function in the etiology of ciliopathies is poorly understood. Here, we sh
Externí odkaz:
https://doaj.org/article/64cd3655c3764130ba8e0811b1fe5fe9
Autor:
Judith Jing Wen Wong, Maria Brandal Berstad, Ane Sofie Viset Fremstedal, Kristian Berg, Sebastian Patzke, Vigdis Sørensen, Qian Peng, Pål Kristian Selbo, Anette Weyergang
Publikováno v:
Cancers, Vol 12, Iss 2, p 417 (2020)
Lysosomal accumulation of sunitinib has been suggested as an underlying mechanism of resistance. Here, we investigated if photochemical internalization (PCI), a technology for cytosolic release of drugs entrapped in endosomes and lysosomes, would act
Externí odkaz:
https://doaj.org/article/f8186c314d1b4650ab2e0e732cab88eb
Autor:
Ada H V Repetto-Llamazares, Roy H Larsen, Sebastian Patzke, Karianne G Fleten, David Didierlaurent, Alexandre Pichard, Jean Pierre Pouget, Jostein Dahle
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128816 (2015)
177Lu-DOTA-HH1 (177Lu-HH1) is a novel anti-CD37 radioimmunoconjugate developed to treat non-Hodgkin lymphoma. Mice with subcutaneous Ramos xenografts were treated with different activities of 177Lu-HH1, 177Lu-DOTA-rituximab (177Lu-rituximab) and non-
Externí odkaz:
https://doaj.org/article/16151617b83e424ea9f24337903813b1
Autor:
Johan Sternemalm, Stefan Geimer, Kari-Anne M Frikstad, Kay O Schink, Trond Stokke, Sebastian Patzke
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134789 (2015)
Deleterious mutations of the Centrosome/Spindle Pole associated Protein 1 gene, CSPP1, are causative for Joubert-syndrome and Joubert-related developmental disorders. These disorders are defined by a characteristic mal-development of the brain, but f
Externí odkaz:
https://doaj.org/article/dce97ab5960547fd95facee072d143e8
Autor:
Heidi Lyng, Therese Seierstad, Bjørn Brennhovd, Sebastian Patzke, A. Kathrine Lie, Ljiljana Vlatkovic, Eva-Katrine Aarnes, Harald Bull Ragnum, Knut Håkon Hole, Tord Hompland
Construction of histology images of cell density and blood vessel density.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::647ceafeb3d32f6eb0d95e7e2c64bd55
https://doi.org/10.1158/0008-5472.22419965
https://doi.org/10.1158/0008-5472.22419965
Autor:
Heidi Lyng, Therese Seierstad, Bjørn Brennhovd, Sebastian Patzke, A. Kathrine Lie, Ljiljana Vlatkovic, Eva-Katrine Aarnes, Harald Bull Ragnum, Knut Håkon Hole, Tord Hompland
Pimonidazole immunoscore versus time after administration, DWI parameters and histology parameters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b18ad72d2bf940c8eaba4faf8eb7ffb
https://doi.org/10.1158/0008-5472.22419977.v1
https://doi.org/10.1158/0008-5472.22419977.v1