Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Sebastian P. Fernandez"'
Autor:
Lauren M. Reynolds, Aylin Gulmez, Sophie L. Fayad, Renan Costa Campos, Daiana Rigoni, Claire Nguyen, Tinaïg Le Borgne, Thomas Topilko, Domitille Rajot, Clara Franco, Sebastian P. Fernandez, Fabio Marti, Nicolas Heck, Alexandre Mourot, Nicolas Renier, Jacques Barik, Philippe Faure
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract How nicotine acts on developing neurocircuitry in adolescence to promote later addiction vulnerability remains largely unknown, but may hold the key for informing more effective intervention efforts. We found transient nicotine exposure in e
Externí odkaz:
https://doaj.org/article/95c3d968178b496c9ea5ba0da1168e28
Autor:
Patricia Bermudez-Martin, Jérôme A. J. Becker, Nicolas Caramello, Sebastian P. Fernandez, Renan Costa-Campos, Juliette Canaguier, Susana Barbosa, Laura Martinez-Gili, Antonis Myridakis, Marc-Emmanuel Dumas, Aurélia Bruneau, Claire Cherbuy, Philippe Langella, Jacques Callebert, Jean-Marie Launay, Joëlle Chabry, Jacques Barik, Julie Le Merrer, Nicolas Glaichenhaus, Laetitia Davidovic
Publikováno v:
Microbiome, Vol 9, Iss 1, Pp 1-23 (2021)
Abstract Background Autism spectrum disorders (ASD) are associated with dysregulation of the microbiota-gut-brain axis, changes in microbiota composition as well as in the fecal, serum, and urine levels of microbial metabolites. Yet a causal relation
Externí odkaz:
https://doaj.org/article/528d90be0f624b76bc049fae162ed6dc
Autor:
Sebastian P. Fernandez, Loïc Broussot, Fabio Marti, Thomas Contesse, Xavier Mouska, Mariano Soiza-Reilly, Hélène Marie, Philippe Faure, Jacques Barik
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Dopamine neurons in the ventral tegmental area (VTA) are implicated in depressive-like behaviors. Here, the authors show that cholinergic inputs to the VTA from the laterodorsal tegmentum regulate intrinsic plasticity of VTA DA neurons to mediate str
Externí odkaz:
https://doaj.org/article/7a4f1423a5b94bea8614630b86067284
Autor:
Paula A. Pousinha, Xavier Mouska, Daniela Bianchi, Mariana Temido-Ferreira, Joana Rajão-Saraiva, Rui Gomes, Sebastian P. Fernandez, Ana Rita Salgueiro-Pereira, Carine Gandin, Elisabeth F. Raymond, Jacques Barik, Romain Goutagny, Ingrid Bethus, Luisa V. Lopes, Michele Migliore, Hélène Marie
Publikováno v:
Cell Reports, Vol 29, Iss 2, Pp 317-331.e5 (2019)
Summary: There is a growing consensus that Alzheimer's disease (AD) involves failure of the homeostatic machinery, which underlies the firing stability of neural circuits. What are the culprits leading to neuron firing instability? The amyloid precur
Externí odkaz:
https://doaj.org/article/90855fdcacba470a93f8234bea3604cb
Autor:
Marie-Charlotte Allichon, Ying Zhu, Roman Walle, Vincent Kappes, Andry Andrianarivelo, Naguib Mechawar, Jocelyne Caboche, Jacques Barik, Nicolas Heck, Paula A. Pousinha, Peter Vanhoutte, Véronique De Smedt-Peyrusse, Pierre Trifilieff, Gustavo Turecki, Anna Petitbon, Estefani Saint-Jour, Sebastian P. Fernandez, Vanesa Ortiz, Jonathan A. Javitch, Charlène Joséphine, Alexis-Pierre Bemelmans, Sandrine Betuing
Publikováno v:
Science Advances
Science Advances, 2021, 7, pp.1-17. ⟨10.1126/sciadv.abg5970⟩
Science Advances, American Association for the Advancement of Science (AAAS), 2021, 7, pp.1-17. ⟨10.1126/sciadv.abg5970⟩
Science Advances, 2021, 7 (43), ⟨10.1126/sciadv.abg5970⟩
Science Advances, American Association for the Advancement of Science (AAAS), 2021, 7 (43), ⟨10.1126/sciadv.abg5970⟩
Science Advances, 2021, 7, pp.1-17. ⟨10.1126/sciadv.abg5970⟩
Science Advances, American Association for the Advancement of Science (AAAS), 2021, 7, pp.1-17. ⟨10.1126/sciadv.abg5970⟩
Science Advances, 2021, 7 (43), ⟨10.1126/sciadv.abg5970⟩
Science Advances, American Association for the Advancement of Science (AAAS), 2021, 7 (43), ⟨10.1126/sciadv.abg5970⟩
Description
D2R-NMDAR receptor heteromers are potential therapeutic targets in drug addiction.
Addictive drugs increase dopamine in the nucleus accumbens (NAc), where it persistently shapes excitatory glutamate transmission and hijacks natu
D2R-NMDAR receptor heteromers are potential therapeutic targets in drug addiction.
Addictive drugs increase dopamine in the nucleus accumbens (NAc), where it persistently shapes excitatory glutamate transmission and hijacks natu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ffa97c632501a58bb02dd686d8d1015
https://hal.science/hal-03389497/document
https://hal.science/hal-03389497/document
Autor:
Joëlle Chabry, R. Costa-Campos, Jean-Marie Launay, Philippe Langella, Laura Martinez-Gili, Nicolas Caramello, Claire Cherbuy, Antonis Myridakis, Jacques Barik, Laetitia Davidovic, Aurélia Bruneau, Julie Le Merrer, Sebastian P. Fernandez, Jacques Callebert, Susana Barbosa, Marc-Emmanuel Dumas, Nicolas Glaichenhaus, Juliette Canaguier, Patricia Bermudez-Martin, Jérôme A.J. Becker
Publikováno v:
Microbiome
Microbiome, BioMed Central, 2021, 9 (1), pp.1-23. ⟨10.1186/s40168-021-01103-z⟩
Microbiome, BioMed Central, 2021, 9 (1), pp.157. ⟨10.1186/s40168-021-01103-z⟩
Microbiome, BioMed Central, 2021, 9 (1), pp.1-23. ⟨10.1101/2020.05.18.101147⟩
Microbiome, BioMed Central, 2021, 9 (1), ⟨10.1186/s40168-021-01103-z⟩
Microbiome, 2021, 9 (1), pp.1-23. ⟨10.1186/s40168-021-01103-z⟩
Microbiome, Vol 9, Iss 1, Pp 1-23 (2021)
Microbiome, BioMed Central, 2021, 9 (1), pp.1-23. ⟨10.1186/s40168-021-01103-z⟩
Microbiome, BioMed Central, 2021, 9 (1), pp.157. ⟨10.1186/s40168-021-01103-z⟩
Microbiome, BioMed Central, 2021, 9 (1), pp.1-23. ⟨10.1101/2020.05.18.101147⟩
Microbiome, BioMed Central, 2021, 9 (1), ⟨10.1186/s40168-021-01103-z⟩
Microbiome, 2021, 9 (1), pp.1-23. ⟨10.1186/s40168-021-01103-z⟩
Microbiome, Vol 9, Iss 1, Pp 1-23 (2021)
Background Autism spectrum disorders (ASD) are associated with dysregulation of the microbiota-gut-brain axis, changes in microbiota composition as well as in the fecal, serum, and urine levels of microbial metabolites. Yet a causal relationship betw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dae1f3fb97915219b8e415a42fc0d81
https://hal.archives-ouvertes.fr/hal-03434993/document
https://hal.archives-ouvertes.fr/hal-03434993/document
Autor:
Loïc Broussot, Thomas Contesse, Renan Costa-Campos, Christelle Glangetas, Léa Royon, Hugo Fofo, Thomas Lorivel, François Georges, Sebastian P. Fernandez, Jacques Barik
Publikováno v:
Molecular psychiatry. 27(12)
Freezing is a conserved defensive behaviour that constitutes a major stress-coping mechanism. Decades of research have demonstrated a role of the amygdala, periaqueductal grey and hypothalamus as core actuators of the control of fear responses, inclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc3c282baf42123d4c89006b5fd6ee8
https://pubmed.ncbi.nlm.nih.gov/36127430
https://pubmed.ncbi.nlm.nih.gov/36127430
Autor:
Thomas Contesse, Jacques Barik, Hugo Fofo, Peter Vanhoutte, Loïc Broussot, Sebastian P. Fernandez
Publikováno v:
Neuropharmacology
Neuropharmacology, 2021, pp.108534. ⟨10.1016/j.neuropharm.2021.108534⟩
Neuropharmacology, Elsevier, 2021, pp.108534. ⟨10.1016/j.neuropharm.2021.108534⟩
Neuropharmacology, 2021, pp.108534. ⟨10.1016/j.neuropharm.2021.108534⟩
Neuropharmacology, Elsevier, 2021, pp.108534. ⟨10.1016/j.neuropharm.2021.108534⟩
International audience; Stress has been acknowledged as one of the main risk factors for the onset of psychiatric disorders. Social stress is the most common type of stressor encountered in our daily lives. Uncovering the molecular determinants of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e33515846c2001092571ab1c111ed7
https://hal.sorbonne-universite.fr/hal-03186855
https://hal.sorbonne-universite.fr/hal-03186855
Autor:
Imane Moutkine, Bruno P. Guiard, Stéphane Doly, Pothitos M. Pitychoutis, Manuel Mameli, Anna Tchenio, Emily Quentin, Sophie M. Banas, Sebastian P. Fernandez, Silvina L. Diaz, Aude Muzerelle, Arnauld Belmer, Anne Roumier, Luc Maroteaux
Publikováno v:
Neuropsychopharmacology
Neuropsychopharmacology, 2018, 43 (7), pp.1623-1633. ⟨10.1038/s41386-018-0013-0⟩
Neuropsychopharmacology, Nature Publishing Group, 2018, 43 (7), pp.1623-1633. ⟨10.1038/s41386-018-0013-0⟩
Neuropsychopharmacology, 2018, 43 (7), pp.1623-1633. ⟨10.1038/s41386-018-0013-0⟩
Neuropsychopharmacology, Nature Publishing Group, 2018, 43 (7), pp.1623-1633. ⟨10.1038/s41386-018-0013-0⟩
Serotonin is a neurotransmitter involved in many psychiatric diseases. In humans, a lack of 5-HT2B receptors is associated with serotonin-dependent phenotypes, including impulsivity and suicidality. A lack of 5-HT2B receptors in mice eliminates the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0208833b60b5578b40440b5306fd678
https://doi.org/10.1038/s41386-018-0013-0
https://doi.org/10.1038/s41386-018-0013-0
Autor:
Sebastian P. Fernandez, Sophie Scotto-Lomassese, José M. Delgado-García, Aude Muzerelle, Jacques Barik, Patricia Gaspar, Agnès Gruart
Publikováno v:
Neuropsychopharmacology. 42:512-523
Serotonin (5-HT) deficiency occurs in a number of brain disorders that affect cognitive function. However, a direct causal relationship between 5-HT hypo-transmission and memory and underlying mechanisms has not been established. We used mice with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f137a4a4cfebe92b04ff375abc7dc2c
https://doi.org/10.1038/npp.2016.134
https://doi.org/10.1038/npp.2016.134