Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Sebastian Ohse"'
Publikováno v:
PeerJ Computer Science, Vol 5, p e231 (2019)
The rise of high-throughput technologies in the domain of molecular and cell biology, as well as medicine, has generated an unprecedented amount of quantitative high-dimensional data. Public databases at present make a wealth of this data available,
Externí odkaz:
https://doaj.org/article/f66d83a466e14b8d8ec1538d4cb697bc
Autor:
Sebastian Ohse, Hendrik Dienemann, Thomas Muley, Michael Meister, I. Titkova, Dmytro Dvornikov, Felix Herth, Arne Warth, Ursula Klingmüller, Marcel Schilling, Magdalena Szczygiel, Marc A Schneider, Michael Thomas, Hauke Busch, Jens Timmer, Marcus Rosenblatt, Melanie Boerries
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Scientific Reports
In lung cancer a deregulation of Transforming Growth Factor-β (TGFβ) signaling has been observed. Yet, the impact of TGFβ in squamous cell carcinoma of the lung (LUSC) remained to be determined. We combined phenotypic and transcriptome-wide studie
Autor:
Marc A. Schneider, C. Xu, Hauke Busch, Melanie Boerries, Roland Eils, E. Gladilin, Sebastian Ohse, Michael Meister
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Importance of growth factor (GF) signaling in cancer progression is widely acknowledged. Transforming growth factor beta (TGFβ) is known to play a key role in epithelial-to-mesenchymal transition (EMT) and metastatic cell transformation that are cha
Autor:
Sebastian Ohse, Bernard C. Lo, Diane M. Martin, Angela Chiang, Steven T. Lund, Jörg Bohlmann, Omid Toub
Publikováno v:
Proceedings of the National Academy of Sciences. 106:7245-7250
Terpenoid volatiles are important information molecules that enable pollinators to locate flowers and may protect reproductive tissues against pathogens or herbivores. Inflorescences of grapevine ( Vitis vinifera L.) are composed of tiny green flower
Autor:
Fritz Boege, Melanie Boerries, Alexander Bürkle, Brigitte Royer-Pokora, Maria Moreno-Villanueva, Hauke Busch, Sebastian Ohse, Julia Tigges, Barbara Hildebrandt, Sabine Seggewiß, Faiza Kalfalah, Regina Walter
Publikováno v:
Aging (Albany NY)
Dermal fibroblasts provide a paradigmatic model of cellular adaptation to long-term exogenous stress and ageing processes driven thereby. Here we addressed whether fibroblast ageing analysed ex vivo entails genome instability. Dermal fibroblasts from
Autor:
René Deenen, Karl Köhrer, Beatrice Bornholz, Sebastian Ohse, Stefan Sobek, Faiza Kalfalah, Fritz Boege, Ellen Fritsche, Melanie Boerries, Jean Krutmann, Julia Tigges, Christine Götz-Rösch, Hauke Busch
Publikováno v:
Experimental gerontology. 56
Extrinsic skin ageing converges on the dermis, a post-mitotic tissue compartment consisting of extracellular matrix and long-lived fibroblasts prone to damage accumulation and maladaptation. Aged human fibroblasts exhibit mitochondrial and nuclear dy