Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Sebastian O Stead"'
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Akademický článek
Rapamycin and abundant TCR stimulation are required for the generation of stable human induced regulatory T cells
Autor: Juewan Kim, Christopher M Hope, Griffith B Perkins, Sebastian O Stead, Jacqueline C Scaffidi, Francis D Kette, Robert P Carroll, Simon C Barry, Patrick Toby Coates
Publikováno v: Clinical & Translational Immunology, Vol 9, Iss 12, Pp n/a-n/a (2020)
Abstract Objectives Regulatory T cells (Tregs) are a vital sub‐population of CD4+ T cells with major roles in immune tolerance and homeostasis. Given such properties, the use of regulatory T cells for immunotherapies has been extensively investigat
Externí odkaz: https://doaj.org/article/9cfb460159be4df5ac162afa53caccac
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2
Murine and Non-Human Primate Dendritic Cell Targeting Nanoparticles for in Vivo Generation of Regulatory T-Cells
Autor: Robert P. Carroll, Patrick T. Coates, Juewan Kim, Chris Drogemuller, Nicolas H. Voelcker, Francis D. Kette, Jean-Olivier Durand, Sebastian O. Stead, Frédérique Cunin, Steven J. P. McInnes, Kisha N. Sivanathan, Eduardo J. Cueto-Díaz, Svjetlana Kireta
Publikováno v: ACS Nano
ACS Nano, American Chemical Society, 2018, 12 (7), pp.6637-6647. ⟨10.1021/acsnano.8b01625⟩
International audience; Porous silicon nanoparticles (pSiNP), modified to target dendritic cells (DC), provide an alternate strategy for the delivery of immunosuppressive drugs. Here, we aimed to develop a DC-targeting pSiNP displaying c-type lectin,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::409100435f24ceb05267ef66cf001337
https://doi.org/10.1021/acsnano.8b01625
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7
Manipulating human dendritic cell phenotype and function with targeted porous silicon nanoparticles
Autor: Shilpanjali Jesudason, Robert P. Carroll, Peter D. Rose, Jean Durand, Darling Rojas-Canales, Sebastian O. Stead, Steven J. P. McInnes, David Warther, Nicolas H. Voelcker, Svjetlana Kireta, Frédérique Cunin, P. Toby Coates, Chris Drogemuller
Publikováno v: Biomaterials
Biomaterials, Elsevier, 2018, 155, pp.92-102. ⟨10.1016/j.biomaterials.2017.11.017⟩
International audience; Dendritic cells (DC) are the most potent antigen-presenting cells and are fundamental for the establishment of transplant tolerance. The Dendritic Cell-Specific Intracellular adhesion molecule-3-Grabbing Non-integrin (DC-SIGN;
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e996d195e43f9750e980e3cd3b3e3224
https://hal.archives-ouvertes.fr/hal-03124420
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