Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Sebastian Niedenführ"'
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 10, p e1006533 (2018)
Science revolves around the best way of conducting an experiment to obtain insightful results. Experiments with maximal information content can be found by computational experimental design (ED) strategies that identify optimal conditions under which
Externí odkaz:
https://doaj.org/article/7a5c58c52d174260aef9b2b9031f0f14
Autor:
Christian P. Haas, Maximilian Lübbesmeyer, Edward H. Jin, Matthew A. McDonald, Brent A. Koscher, Nicolas Guimond, Laura Di Rocco, Henning Kayser, Samuel Leweke, Sebastian Niedenführ, Rachel Nicholls, Emily Greeves, David M. Barber, Julius Hillenbrand, Giulio Volpin, Klavs F. Jensen
Automation and digitalization solutions in the field of small molecule synthesis face new challenges for chemical reaction analysis, especially in the field of high-performance liquid chromatography (HPLC). Chromatographic data remains locked in vend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feb821ec2e61a7da416aceededba4451
https://doi.org/10.26434/chemrxiv-2022-0pv2d
https://doi.org/10.26434/chemrxiv-2022-0pv2d
Autor:
Andreas Schuppert, Alireza Ehsani, Sebastian Niedenführ, Chrysoula Dimitra Kappatou, Alexander Mitsos, Adel Mhamdi
Publikováno v:
Computers & Chemical Engineering. 142:107004
Compliance with Quality by Design (QbD) constitutes a major challenge in biopharmaceuticals. Monoclonal antibodies (mAbs) represent a significant biopharmaceutical product class, typically produced in mammalian cell cultures. A key quality attribute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f50fcbdbcc4a7b3eccd77db1f2233d6
https://doi.org/10.1016/j.compchemeng.2020.107004
https://doi.org/10.1016/j.compchemeng.2020.107004
Autor:
Sebastian Niedenführ, Hanna Borlinghaus, Marcel Leist, Tanja Waldmann, Simon Gutbier, Liang Zhao, Salah Azzouzi, Christin Zasada, Katharina Nöh, Martin Cerff, Thomas Hartung, Jochem Gätgens, Lena Smirnova, Jörg Bergemann, Johannes Delp, Martin Beyss, Stefan Kempa, Falk Schreiber
Publikováno v:
Toxicology and Applied Pharmacology
Developmental neurotoxicity (DNT) may be induced when chemicals disturb a key neurodevelopmental process, and many tests focus on this type of toxicity. Alternatively, DNT may occur when chemicals are cytotoxic only during a specific neurodevelopment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea5d19467dc1bf127e67ba8610bd89de
Publikováno v:
Computers & Chemical Engineering
Model discrimination identifies a mathematical model that usefully explains and predicts a given system’s behaviour. Researchers will often have several models, i.e. hypotheses, about an underlying system mechanism, but insufficient experimental da
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::122bc6fe4860173a84b5354886482c6a
Autor:
Katharina Nöh, Patricia T. N. van Dam, Sebastian Niedenführ, S. Aljoscha Wahl, Camilo A. Suarez-Mendez, Angela ten Pierick
Publikováno v:
Biotechnology and Bioengineering. 113:1137-1147
Fluxomics and metabolomics are crucial tools for metabolic engineering and biomedical analysis to determine the in vivo cellular state. Especially, the application of (13)C isotopes allows comprehensive insights into the functional operation of cellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1de02abc9e3d445c89792f6c31fe469
https://doi.org/10.1002/bit.25859
https://doi.org/10.1002/bit.25859
Autor:
Martin Cerff, Hanna Borlinghaus, Liang Zhao, Jochem Gätgens, Stefan Kempa, Jörg Bergemann, Johannes Delp, Christin Zasada, Salah Azzouzi, Sebastian Niedenführ, Tanja Waldmann, Falk Schreiber, Thomas Hartung, Marcel Leist, Simon Gutbier, Lena Smirnova, Katharina Nöh, Martin Beyss
Publikováno v:
Toxicology and Applied Pharmacology. 372:70
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f093a3f91dc024c371327c335530a40
https://doi.org/10.1016/j.taap.2019.04.010
https://doi.org/10.1016/j.taap.2019.04.010
Publikováno v:
Fundamental Bioengineering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84e1f1f27b6907bc51376442ea7ee312
https://doi.org/10.1002/9783527697441.ch05
https://doi.org/10.1002/9783527697441.ch05
Autor:
Sebastian, Niedenführ, Angela, ten Pierick, Patricia T N, van Dam, Camilo A, Suarez-Mendez, Katharina, Nöh, S Aljoscha, Wahl
Publikováno v:
Biotechnology and bioengineering. 113(5)
Fluxomics and metabolomics are crucial tools for metabolic engineering and biomedical analysis to determine the in vivo cellular state. Especially, the application of (13)C isotopes allows comprehensive insights into the functional operation of cellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::273ee2680370aadb52d5996c9844a736
https://pubmed.ncbi.nlm.nih.gov/26479486
https://pubmed.ncbi.nlm.nih.gov/26479486
Autor:
Sabrina Witthoff, Sebastian Niedenführ, Michael Bott, Katharina Nöh, Jan Marienhagen, Katja Schmitz, Stephan Noack
Methanol is already an important carbon feedstock in the chemical industry, but it has found only limited application in biotechnological production processes. This can be mostly attributed to the inability of most microbial platform organisms to uti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b189352f132dfa477cf39d54e1e57f48
https://europepmc.org/articles/PMC4345391/
https://europepmc.org/articles/PMC4345391/