Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Sebastian N. Wirtz"'
Autor:
Dominik Ruppelt, Marius F. W. Trollmann, Taulant Dema, Sebastian N. Wirtz, Hendrik Flegel, Sophia Mönnikes, Stephanie Grond, Rainer A. Böckmann, Claudia Steinem
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Recently, a novel cyclo-heptapeptide composed of alternating d,l-amino acids and a unique thiazolidine heterocycle, called lugdunin, was discovered, which is produced by the nasal and skin commensal Staphylococcus lugdunensis. Lugdunin displ
Externí odkaz:
https://doaj.org/article/38880531d1434ebb8518ed3032bab98c
Autor:
Stephanie Grond, Bernhard Krismer, Martin C. Konnerth, Nadine A. Schilling, Hubert Kalbacher, Johannes Schumacher, Anne Berscheid, Sebastian N. Wirtz, Julian S. Saur, Alexander Zipperer, José M. Beltrán‐Beleña, Andreas Peschel, Claudia Steinem, Heike Brötz-Oesterhelt
Publikováno v:
Angewandte Chemie. 131:9333-9338
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5aa11c8e6a856de4b198267184d99345
https://doi.org/10.1002/ange.201901589
https://doi.org/10.1002/ange.201901589
Autor:
Stephanie Grond, Nadine A. Schilling, Bernhard Krismer, Julian S. Saur, Sebastian N. Wirtz, Andreas Peschel
Publikováno v:
Journal of medicinal chemistry. 64(7)
A new solid-phase peptide synthesis and bioprofiling of the antimicrobial activity of lugdunin, a fibupeptide, enable a comprehensive structure–activity relationship (SAR) study (MRSA Staphylococcu...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45d1b2eeff6ce615d532771b97262d0d
https://pubmed.ncbi.nlm.nih.gov/33779184
https://pubmed.ncbi.nlm.nih.gov/33779184
Autor:
Sebastian N. Wirtz, Martin C. Konnerth, Julian S. Saur, Simon Heilbronner, Bernhard Krismer, Alexander Zipperer, Andreas Peschel, Sophia Krauss, Stephanie Grond, Benjamin O. Torres Salazar
Publikováno v:
Antimicrobial Agents and Chemotherapy
Lugdunin is the first reported nonribosomally synthesized antibiotic from human microbiomes. Its production by the commensal Staphylococcus lugdunensis eliminates the pathogen Staphylococcus aureus from human nasal microbiomes. The cycloheptapeptide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87908d91bd5c2c1cea1ed4896519fd33
https://doi.org/10.1128/aac.01734-20
https://doi.org/10.1128/aac.01734-20