Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Sebastian Memczak"'
Autor:
Andranik Ivanov, Sebastian Memczak, Emanuel Wyler, Francesca Torti, Hagit T. Porath, Marta R. Orejuela, Michael Piechotta, Erez Y. Levanon, Markus Landthaler, Christoph Dieterich, Nikolaus Rajewsky
Publikováno v:
Cell Reports, Vol 10, Iss 2, Pp 170-177 (2015)
Circular RNAs (circRNAs) are a large class of animal RNAs. To investigate possible circRNA functions, it is important to understand circRNA biogenesis. Besides human ALU repeats, sequence features that promote exon circularization are largely unknown
Externí odkaz:
https://doaj.org/article/c91cfa89a3db4f71a43ef062808a8763
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141214 (2015)
Covalently closed circular RNA molecules (circRNAs) have recently emerged as a class of RNA isoforms with widespread and tissue specific expression across animals, oftentimes independent of the corresponding linear mRNAs. circRNAs are remarkably stab
Externí odkaz:
https://doaj.org/article/8486d86130e444c084d04be0325fe327
Publikováno v:
Nature Metabolism. 2:293-302
Organismal ageing results from interlinked molecular changes in multiple organs over time. The study of ageing at the molecular level is complicated by varying decay characteristics and kinetics-both between and within organs-driven by intrinsic and
Publikováno v:
Cell Stem Cell. 28:5-7
Summary The regeneration potential of axons projecting from retinal ganglion cells (RGCs) is lost shortly after birth. In Nature, Lu et al. (2020) demonstrate that epigenetic reprogramming of RGCs by overexpression of Oct4, Sox2, and Klf4 leads to ax
Autor:
Tomoaki Hishida, Mako Yamamoto, Yuriko Hishida-Nozaki, Changwei Shao, Ling Huang, Chao Wang, Kensaku Shojima, Yuan Xue, Yuqing Hang, Maxim Shokhirev, Sebastian Memczak, Sanjeeb Kumar Sahu, Fumiyuki Hatanaka, Ruben Rabadan Ros, Matthew B. Maxwell, Jasmine Chavez, Yanjiao Shao, Hsin-Kai Liao, Paloma Martinez-Redondo, Isabel Guillen-Guillen, Reyna Hernandez-Benitez, Concepcion Rodriguez Esteban, Jing Qu, Michael C. Holmes, Fei Yi, Raymond D. Hickey, Pedro Guillen Garcia, Estrella Nuñez Delicado, Antoni Castells, Josep M. Campistol, Yang Yu, Diana C. Hargreaves, Akihiro Asai, Pradeep Reddy, Guang-Hui Liu, Juan Carlos Izpisua Belmonte
Publikováno v:
Cell reports. 39(4)
Mammals have limited regenerative capacity, whereas some vertebrates, like fish and salamanders, are able to regenerate their organs efficiently. The regeneration in these species depends on cell dedifferentiation followed by proliferation. We genera
Publikováno v:
Trends in molecular medicine. 27(3)
Genome editing holds great promise for treating a range of human genetic diseases. While emerging clustered regularly interspaced short-palindromic repeats (CRISPR) technologies allow editing of the nuclear genome, it is still not possible to precise
Publikováno v:
The Journal of Cardiovascular Aging. 2:39
Publikováno v:
Cell Research. 29:687-689
Autor:
Petar Glažar, Aisha V. Sauer, Nikolaus Rajewsky, Alessandro Aiuti, Philipp G. Maass, Luisa Schreyer, Sebastian Memczak, Gunnar Dittmar, Okan Toka, Friedrich C. Luft, Irene Hollfinger
Publikováno v:
Journal of Molecular Medicine (Berlin, Germany)
Cellular circular RNAs (circRNAs) are generated by head-to-tail splicing and are present in all multicellular organisms studied so far. Recently, circRNAs have emerged as a large class of RNA which can function as post-transcriptional regulators. It
Publikováno v:
Nature metabolism. 2(4)
Organismal ageing results from interlinked molecular changes in multiple organs over time. The study of ageing at the molecular level is complicated by varying decay characteristics and kinetics-both between and within organs-driven by intrinsic and