Preclinical evaluation of an 18F-labeled N ε-acryloyllysine piperazide for covalent targeting of transglutaminase 2

Autor: Robert Wodtke, Markus Laube, Sandra Hauser, Sebastian Meister, Friedrich-Alexander Ludwig, Steffen Fischer, Klaus Kopka, Jens Pietzsch, Reik Löser

Publikováno v: EJNMMI Radiopharmacy and Chemistry, Vol 9, Iss 1, Pp 1-25 (2024)

Abstract Background Transglutaminase 2 (TGase 2) is a multifunctional protein and has a prominent role in various (patho)physiological processes. In particular, its transamidase activity, which is rather latent under physiological conditions, gains i

Externí odkaz: https://doaj.org/article/22eb1f3fd9ac49ebabcd4cbb268205c3

Eutrophication and restoration in temperate lakes

Autor: Sebastian Meis, Bryan M. Spears, Iain D. M. Gunn, Justyna Olszewska, Linda May

Publikováno v: IOP Conference Series: Earth and Environmental Science. 535:012001

Eutrophication affects many lakes and reservoirs worldwide. It is caused by excessive amounts of nutrients entering waterbodies from their catchments, mainly due to human activity. The main sources of these nutrients are discharges from industry and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04f3694538d3b351e0ffe8c501c22bed
https://doi.org/10.1088/1755-1315/535/1/012001

Assessing the mode of action of Phoslock® in the control of phosphorus release from the bed sediments in a shallow lake (Loch Flemington, UK)

Autor: Sebastian Meis, Bryan M. Spears, Stephen C. Maberly, Rupert Gordon Perkins

Publikováno v: Water Research. 47:4460-4473

Phoslock(®) is increasingly used worldwide to control sediment phosphorus (P) release and cyanobacterial blooms despite the fact that little is known about its mode of action in lake bed sediments. This study quantified the effects of Phoslock(®) o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c597460f349b27c7b520568492f019f5
https://doi.org/10.1016/j.watres.2013.05.017

Geo-Engineering in Lakes: A Crisis of Confidence?

Autor: Miquel Lürling, Tristan Hatton-Ellis, Wei Li, Kasper Reitzel, Sara Egemose, David P. Hamilton, Nicholas Corker, Gang Pan, Stephen C. Maberly, Said Yasseri, Brian Moss, Andy Bruere, Brian J. Huser, Sebastian Meis, Ellie Mackay, Grant Douglas, Bryan M. Spears, Geoff Phillips

Publikováno v: Environmental Science and Technology 48 (2014) 17
Environmental Science and Technology, 48(17), 9977-9979
Spears, B M, Maberly, S C, Pan, G, Mackay, E, Bruere, A, Corker, N, Douglas, G, Egemose, S, Hamilton, D, Hatton-Ellis, T, Huser, B, Li, W, Meis, S, Moss, B, Lurling, M, Phillips, G, Yasseri, S & Reitzel, K 2014, ' Geo-Engineering in lakes : A crisis of confidence ', Environmental Science and Technology, vol. 48, no. 17, pp. 9977–9979 . https://doi.org/10.1021/es5036267

The effective management of lakes suffering from eutrophication is confounded by a mosaic of interactions and feedbacks that are difficult to manipulate. For example, in lake processes can delay the relinquishment of legacy phosphorus (P) manifested

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6411171744fbea44d73e3d49133b04d
https://doi.org/10.1021/es5036267

A meta-analysis of water quality and aquatic macrophyte responses in 18 lakes treated with lanthanum modified bentonite (Phoslock(®))

Autor: Helen Woods, Genevieve Madgwick, Kate E. Waters, Alanna Moore, Gertrud K. Nürnberg, Iain D. M. Gunn, Frank van Oosterhout, Stephanie Cole, Jo-Anne Pitt, Sebastian Meis, Eleanor B. Mackay, Mitzi M. De Ville, Said Yasseri, Bryan M. Spears, Christopher Andrews, Andrea Kelly, Miquel Lürling

Publikováno v: Water Research, 97, 111-121. Elsevier B.V.
Water Research, 97, 111-121
Water Research 97 (2016)

Lanthanum (La) modified bentonite is being increasingly used as a geo-engineering tool for the control of phosphorus (P) release from lake bed sediments to overlying waters. However, little is known about its effectiveness in controlling P across a w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64e13935c835147405a9ccc92786d2d3
https://pubmed.ncbi.nlm.nih.gov/26433547