Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sebastian MORALES-PISON"'
Autor:
Agustín MÁRQUEZ, Isidora MUJICA, Natalia JORDAN, Pablo BAEZ, Sandra TARQUINIO, Jean NUNES, Daniela ADORNO, Benjamín MARTÍNEZ, Sebastian MORALES-PISON, Ricardo FERNANDEZ-RAMIRES
Publikováno v:
Brazilian Oral Research, Vol 37 (2023)
Abstract This study aimed to analyze the molecular characteristics of oral epithelial dysplasia (OED), highlighting the pathways and variants of genes that are frequently mutated in oral squamous cell carcinoma (OSCC) and other cancers. Ten archival
Externí odkaz:
https://doaj.org/article/7c07a7039f71493eaf1f0ea277b40780
Autor:
Sebastian Morales-Pison, Patricio Gonzalez-Hormazabal, Julio C. Tapia, Alexis Salas-Burgos, Sandra Ampuero, Fernando Gómez, Enrique Waugh, José Miguel Reyes, Lilian Jara
Publikováno v:
Biological Research, Vol 55, Iss 1, Pp 1-11 (2022)
Abstract Background Driver mutations are the genetic components responsible for tumor initiation and progression. These variants, which may be inherited, influence cancer risk and therefore underlie many familial cancers. The present study examines t
Externí odkaz:
https://doaj.org/article/05d1640173ac4906a08fe7b0724f4c1a
Publikováno v:
Biological Research, Vol 54, Iss 1, Pp 1-19 (2021)
Abstract Breast cancer (BC), a heterogeneous, aggressive illness with high mortality, is essentially a genomic disease. While the high-penetrance genes BRCA1 and BRCA2 play important roles in tumorigenesis, moderate- and low-penetrance genes are also
Externí odkaz:
https://doaj.org/article/007a917cdfe04203b89bd9db2017b297
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Trypanosomatids are a group of primitive unicellular eukaryotes that can cause diseases in plants, insects, animals, and humans. Kinetoplast genome integrity is key to trypanosomatid cell survival and viability. Kinetoplast DNA (kDNA) is usually unde
Externí odkaz:
https://doaj.org/article/05abaac098c44951ba4aa6aa42e376d2
Publikováno v:
Vaccines, Vol 10, Iss 4, p 587 (2022)
Chagas disease is caused by the protozoan Trypanosoma cruzi and is endemic to Central and South America. However, it has spread around the world and affects several million people. Treatment with currently available drugs cause several side effects a
Externí odkaz:
https://doaj.org/article/82bf24be8d01466991c08921e0d0f3c4
Autor:
Solari, Edio Maldonado, Sebastian Morales-Pison, Fabiola Urbina, Claudia Arias, Christian Castillo, Lilian Jara, Aldo
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9472
Fission yeast ribosomal protein genes (RPGs) contain a HomolD box as a core promoter element required for transcription. Some of the RPGs also contain a consensus sequence named HomolE, located upstream of the HomolD box. The HomolE box acts as an up
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::71120c5cc85fc4d9aec9e78cca2fd350
Autor:
Sebastian Morales-Pison, Sarai Morales-González, Ricardo Fernandez-Ramires, Julio C. Tapia, Edio Maldonado, Gloria M. Calaf, Lilian Jara
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 4
Pages: 4041
Volume 24
Issue 4
Pages: 4041
Breast cancer (BC) is the most common cancer among women worldwide. BRCA1/2 are responsible for 16–20% of the risk for hereditary BC. Other susceptibility genes have been identified; Fanconi Anemia Complementation Group M (FANCM) being one of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f04d828a8a1ed8a95082f5e2337d00ed
https://doi.org/10.3390/ijms24044041
https://doi.org/10.3390/ijms24044041
Autor:
Sebastian Morales-Pison, Lilian Jara, Valentina Carrasco, Cristian Gutiérrez-Vera, José Miguel Reyes, Patricio Gonzalez-Hormazabal, Leandro J. Carreño, Julio C. Tapia, Héctor R. Contreras
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 1; Pages: 380
International Journal of Molecular Sciences, Vol 23, Iss 380, p 380 (2022)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 23, Iss 380, p 380 (2022)
International Journal of Molecular Sciences
MicroRNA-423 (miR-423) is highly expressed in breast cancer (BC). Previously, our group showed that the SNP rs6505162:C>A located in the pre-miR-423 was significantly associated with increased familial BC risk in patients with a strong family history
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4623ee694a8971e1678795dd2e27c8df
Publikováno v:
Genes. 13(2)
Transcriptional coactivators play a key role in RNA polymerase II transcription and gene regulation. One of the most important transcriptional coactivators is the Mediator (MED) complex, which is an evolutionary conserved large multiprotein complex.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa4dc2e94d44f549c7027ef176dac7b3
https://pubmed.ncbi.nlm.nih.gov/35205279
https://pubmed.ncbi.nlm.nih.gov/35205279
Publikováno v:
Biological Research
Biological Research v.54 2021
SciELO Chile
CONICYT Chile
instacron:CONICYT
Biological Research, Vol 54, Iss 1, Pp 1-19 (2021)
Biological Research v.54 2021
SciELO Chile
CONICYT Chile
instacron:CONICYT
Biological Research, Vol 54, Iss 1, Pp 1-19 (2021)
Breast cancer (BC), a heterogeneous, aggressive illness with high mortality, is essentially a genomic disease. While the high-penetrance genes BRCA1 and BRCA2 play important roles in tumorigenesis, moderate- and low-penetrance genes are also involved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85d217a24037ecf0fb113bfea8f7994f
https://doi.org/10.1186/s40659-021-00349-z
https://doi.org/10.1186/s40659-021-00349-z