Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sebastian L. B. König"'
Publikováno v:
CHIMIA, Vol 67, Iss 4 (2013)
Single-molecule spectroscopy allows the direct observation of conformational dynamics in individual biomolecules. Here, we describe how single-molecule Förster resonance energy transfer (smFRET) reveals heterogeneous kinetics in the EBS1*/IBS1* inte
Externí odkaz:
https://doaj.org/article/37116d3a970041ef9080a7b8a6bb3486
Autor:
Richard Börner, Danny Kowerko, Mélodie C A S Hadzic, Sebastian L B König, Marc Ritter, Roland K O Sigel
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195277 (2018)
Single-molecule microscopy has become a widely used technique in (bio)physics and (bio)chemistry. A popular implementation is single-molecule Förster Resonance Energy Transfer (smFRET), for which total internal reflection fluorescence microscopy is
Externí odkaz:
https://doaj.org/article/6dd5421c76f74e5e9d52150e9eee4b2a
Autor:
David Egloff, Eva Freisinger, Igor A. Oleinich, Sebastian L. B. König, Roland K. O. Sigel, Meng Zhao
Publikováno v:
ResearcherID
ACS Chem. Biol.
ACS Chem. Biol.
The sequence-specific fluorescence labeling of nucleic acids is a prerequisite for various methods including single-molecule Förster resonance energy transfer (smFRET) for the detailed study of nucleic acid folding and function. Such nucleic acid de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e99d4db1e2696b6e8717364db703b5a2
https://doi.org/10.1021/acschembio.6b00343
https://doi.org/10.1021/acschembio.6b00343
Autor:
Sebastian L. B. König, Oliver Stach, Andrea Holla, Flurin Sturzenegger, Sebastian Doden, Benjamin Schuler, Daniel Nettels
Publikováno v:
Biophysical Journal. 118:225a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1b5d3a94c0ec0d9c894c1a667e3dedf
https://doi.org/10.1016/j.bpj.2019.11.1334
https://doi.org/10.1016/j.bpj.2019.11.1334
Autor:
Richard Börner, Roland K. O. Sigel, Sebastian L. B. König, Danny Kowerko, Mélodie C. A. S. Hadzic
Single-molecule Forster resonance energy transfer (smFRET) is a powerful technique to probe biomolecular structure and dynamics. A popular implementation of smFRET consists of recording fluorescence intensity time traces of surface-immobilized, chrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c04c9f94b6249e1a53669ee9227ad401
https://doi.org/10.5167/uzh-151976
https://doi.org/10.5167/uzh-151976
Autor:
Daniel Nettels, Patrick Ernst, Peer R. E. Mittl, Simon Hansen, Benjamin Schuler, Sebastian L. B. König, Christina Ewald, Christian Reichen, Andreas Plückthun
Publikováno v:
Journal of structural biology. 201(2)
Designed armadillo repeat proteins (dArmRPs) were developed to create a modular peptide binding technology where each of the structural repeats binds two residues of the target peptide. An essential prerequisite for such a technology is a dArmRP geom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::440ad69fb917c23068dc9416d60fc093
https://pubmed.ncbi.nlm.nih.gov/28864298
https://pubmed.ncbi.nlm.nih.gov/28864298
Autor:
Lothar Jänsch, Marco van Ham, Frank Klawonn, Björn Bulitta, Henk Garritsen, Ulrike Lau, Maxi Scheiter, Sebastian L. B. König, Lothar Gröbe
Publikováno v:
Molecular & Cellular Proteomics. 12:1099-1114
The recent Natural Killer (NK) cell maturation model postulates that CD34(+) hematopoietic stem cells (HSC) first develop into CD56(bright) NK cells, then into CD56(dim)CD57(-) and finally into terminally maturated CD56(dim)CD57(+). The molecular mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfb01e92b1d6f6afdc963f7156bcd038
https://doi.org/10.1074/mcp.m112.024596
https://doi.org/10.1074/mcp.m112.024596
Publikováno v:
Biomolecular Concepts, Vol 1, Iss 2, Pp 197-213 (2010)
The helical duplex architecture of DNA was discovered by Francis Crick and James Watson in 1951 and is well known and understood. However, nucleic acids can also adopt alternative structural conformations that are less familiar, although no less biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fee90dd94a5072821a4208b8a4cd90c5
https://doi.org/10.1515/bmc.2010.011
https://doi.org/10.1515/bmc.2010.011
Autor:
Daniela Kruschel, Danny Kowerko, Miriam Skilandat, Mélodie C. A. S. Hadzic, Roland K. O. Sigel, Lucia Cardo, Sebastian L. B. König
Publikováno v:
Proceedings of the National Academy of Sciences
RNA is commonly believed to undergo a number of sequential folding steps before reaching its functional fold, i.e., the global minimum in the free energy landscape. However, there is accumulating evidence that several functional conformations are oft
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4783c05af1b0a03f6fd6a89ae900acca
https://europepmc.org/articles/PMC4371910/
https://europepmc.org/articles/PMC4371910/
Publikováno v:
Nucleic Acids Research
G-quadruplexes and i-motifs are complementary examples of non-canonical nucleic acid substructure conformations. G-quadruplex thermodynamic stability has been extensively studied for a variety of base sequences, but the degree of duplex destabilizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d2ee7a487632ec0dd420eb20de0f191