Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Sebastian Krossa"'
Autor:
Morten Beck Rye, Sebastian Krossa, Martina Hall, Casper van Mourik, Tone F. Bathen, Finn Drabløs, May-Britt Tessem, Helena Bertilsson
Publikováno v:
iScience, Vol 25, Iss 6, Pp 104451- (2022)
Summary: High secretion of the metabolites citrate and spermine is a unique hallmark for normal prostate epithelial cells, and is reduced in aggressive prostate cancer. However, the identity of the genes controlling this biological process is mostly
Externí odkaz:
https://doaj.org/article/c1978d3a0f9542138e117ae053f48e81
Autor:
Maria K. Andersen, Therese S. Høiem, Britt S. R. Claes, Benjamin Balluff, Marta Martin-Lorenzo, Elin Richardsen, Sebastian Krossa, Helena Bertilsson, Ron M. A. Heeren, Morten B. Rye, Guro F. Giskeødegård, Tone F. Bathen, May-Britt Tessem
Publikováno v:
Cancer & Metabolism, Vol 9, Iss 1, Pp 1-13 (2021)
Abstract Background Prostate cancer tissues are inherently heterogeneous, which presents a challenge for metabolic profiling using traditional bulk analysis methods that produce an averaged profile. The aim of this study was therefore to spatially de
Externí odkaz:
https://doaj.org/article/df61ba5185eb4c52a00bbabae2254f07
Autor:
Anne-Kathrin Bartels, Sascha Göttert, Christine Desel, Miriam Schäfer, Sebastian Krossa, Axel J. Scheidig, Joachim Grötzinger, Inken Lorenzen
Publikováno v:
Cellular Physiology and Biochemistry, Vol 52, Iss 4, Pp 850-868 (2019)
Externí odkaz:
https://doaj.org/article/a28e77e5e8e347c889c007c50f6e04be
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract A Disintegrin and Metalloprotease 17 (ADAM17) can cause the fast release of growth factors and inflammatory mediators from the cell surface. Its activity has to be turned on which occurs by various stimuli. The active form can be inactivated
Externí odkaz:
https://doaj.org/article/8e0352618ebd453ea2b6906d705d91f7
Autor:
Kirsten Hattermann, Henrike Gebhardt, Sebastian Krossa, Andreas Ludwig, Ralph Lucius, Janka Held-Feindt, Rolf Mentlein
Publikováno v:
eLife, Vol 5 (2016)
The transmembrane chemokines CX3CL1/fractalkine and CXCL16 are widely expressed in different types of tumors, often without an appropriate expression of their classical receptors. We observed that receptor-negative cancer cells could be stimulated by
Externí odkaz:
https://doaj.org/article/5ad16815532a40649e80806de2d42b27
Autor:
Rebecca Buchholz, Sebastian Krossa, Maria K Andersen, Michael Holtkamp, Michael Sperling, Uwe Karst, May-Britt Tessem
Publikováno v:
Metallomics
A rapid and cost-efficient tissue preparation protocol for laser ablation-inductively coupled plasma-mass spectrometry imaging (LA–ICP–MSI) has been developed within this study as an alternative to the current gold standard using fresh-frozen sam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40f65ab0968deabee30dfc8c34e02e8
Autor:
Finn Drabløs, Martina Hall, May-Britt Tessem, Morten Beck Rye, Sebastian Krossa, Casper van Mourik, Helena Bertilsson, Tone Frost Bathen
BackgroundSecretion of the metabolites citrate and spermine into prostate lumen is a unique hallmark for normal prostate epithelial cells. However, the identity of the genes controlling citrate and spermine secretion remains mostly unknown despite th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4976d4e2816ee6b90478b4926e262933
https://doi.org/10.1101/2021.09.21.461176
https://doi.org/10.1101/2021.09.21.461176
Simultaneous Detection of Zinc and Its Pathway Metabolites Using MALDI MS Imaging of Prostate Tissue
Autor:
May-Britt Tessem, Therese Stork Høiem, Guro F. Giskeødegård, Benjamin Balluff, Helena Bertilsson, Britt S. R. Claes, Sebastian Krossa, Shane R. Ellis, Maria Karoline Andersen, Uwe Karst, Tone Frost Bathen, Rebecca Buchholz, Elin Richardsen, Ron M. A. Heeren
Publikováno v:
Analytical Chemistry, 92(4), 3171-3179. American Chemical Society
Analytical Chemistry
Analytical Chemistry
Levels of zinc, along with its mechanistically related metabolites citrateand aspartate, are widely reported as reduced in prostate cancer compared to healthytissue and are therefore pointed out as potential cancer biomarkers. Previously, it hasonly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8ff98a0f25f59aa3bd00950064056fe
https://hdl.handle.net/10037/17494
https://hdl.handle.net/10037/17494
Autor:
Axel J. Scheidig, Daniela C. Granato, Anne-Kathrin Bartels, Andreas Tholey, Tomas Koudelka, Stefan Düsterhöft, Joachim Grötzinger, Inken Lorenzen, Sebastian Krossa, Sami Yokoo, Adriana Franco Paes Leme, Miriam Schäfer
Publikováno v:
FEBS Letters. 591:3567-3587
The shedding of ectodomains is a crucial mechanism in many physiological and pathological events. A disintegrin and metalloprotease-17 (ADAM17) is a key sheddase involved in essential processes, such as development, regeneration, and immune defense.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b84f3d33f0a2f6ad46432f43466c2498
https://doi.org/10.1002/1873-3468.12858
https://doi.org/10.1002/1873-3468.12858
Autor:
Axel J. Scheidig, Anne-Kathrin Bartels, Christine Desel, Inken Lorenzen, Joachim Grötzinger, Miriam Schäfer, Sebastian Krossa, Sascha Göttert
Publikováno v:
Cellular Physiology and Biochemistry
Cellular Physiology and Biochemistry, Vol 52, Iss 4, Pp 850-868 (2019)
Cellular Physiology and Biochemistry, Vol 52, Iss 4, Pp 850-868 (2019)
Background/Aims: Endoplasmic reticulum (ER)-resident proteins with a C-terminal KDEL ER-retention sequence are captured in the Golgi apparatus by KDEL receptors (KDELRs). The binding of such proteins to these receptors induces their retrograde transp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::079921a8e4e5358f862ef48884775bbc
https://pubmed.ncbi.nlm.nih.gov/30958660
https://pubmed.ncbi.nlm.nih.gov/30958660