Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sebastian Korste"'
Autor:
Elias Haj-Yehia, Sebastian Korste, Robert Jochem, Aldona Lusha, Anna Roth, Nina Dietzel, Josefine Niroomand, Pia Stock, Astrid M. Westendorf, Jan Buer, Ulrike B. Hendgen-Cotta, Tienush Rassaf, Matthias Totzeck
Publikováno v:
International Journal of Cardiology: Heart & Vasculature, Vol 48, Iss , Pp 101269- (2023)
CD47 is a cell surface protein controlling phagocytotic activity of innate immune cells. CD47 blockade was investigated as an immune checkpoint therapy in cancer treatment, enhancing phagocytosis of tumor cells by macrophages. Anti-CD47 treatment als
Externí odkaz:
https://doaj.org/article/3e38543a33e249afba3fe9903646b023
Autor:
Sebastian Korste, Stephan Settelmeier, Lars Michel, Andrea Odersky, Pia Stock, Fabrice Reyes, Elias Haj-Yehia, Markus S. Anker, Anika Grüneboom, Ulrike B. Hendgen-Cotta, Tienush Rassaf, Matthias Totzeck
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6052 (2023)
Cancer survival rates have increased significantly because of improvements in therapy regimes and novel immunomodulatory drugs. Recently, combination therapies of anthracyclines and immune checkpoint inhibitors (ICIs) have been proposed to maximize n
Externí odkaz:
https://doaj.org/article/663aacb6082341939843d1d2a1a8eedb
Autor:
Tienush Rassaf, Matthias Totzeck, Amir A. Mahabadi, Ulrike Hendgen‐Cotta, Sebastian Korste, Stephan Settelmeier, Peter Luedike, Ulf Dittmer, Frank Herbstreit, Thorsten Brenner, Karin Klingel, Mike Hasenberg, Bernd Walkenfort, Matthias Gunzer, Thomas Schlosser, Alexander Weymann, Markus Kamler, Bastian Schmack, Arjang Ruhparwar
Publikováno v:
ESC Heart Failure, Vol 8, Iss 1, Pp 162-166 (2021)
Abstract Coronavirus disease 2019 (COVID‐19) is challenging the care for cardiovascular patients, resulting in serious consequences with increasing mortality in pre‐diseased heart failure patients. In the current state of the pandemic, the physio
Externí odkaz:
https://doaj.org/article/38d8c6170ed1499389bfa3ec5b6a73a7
Autor:
Lars Michel, Raluca I. Mincu, Simone M. Mrotzek, Sebastian Korste, Ulrich Neudorf, Tienush Rassaf, Matthias Totzeck
Publikováno v:
ESC Heart Failure, Vol 7, Iss 2, Pp 423-433 (2020)
Abstract Aims Childhood cancer therapy is associated with a significant risk of therapy‐related cardiotoxicity. This meta‐analysis aims to evaluate cardiac biomarkers for the detection of cancer therapy‐related left ventricular (LV) dysfunction
Externí odkaz:
https://doaj.org/article/9c7ced8031624bcca594b90c48bfc901
Autor:
Simon F. Merz, Sebastian Korste, Lea Bornemann, Lars Michel, Pia Stock, Anthony Squire, Camille Soun, Daniel R. Engel, Julia Detzer, Holger Lörchner, Dirk M. Hermann, Markus Kamler, Joachim Klode, Ulrike B. Hendgen-Cotta, Tienush Rassaf, Matthias Gunzer, Matthias Totzeck
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Detailed characterization of cardiac damage following ischemia/reperfusion injury and detection of occurring inflammatory responses is important for the development of new therapeutic concepts. Here the authors present a method for the three-dimensio
Externí odkaz:
https://doaj.org/article/3e96cf3e564a4e068419e2da632f2557
Autor:
Lars Michel, Sebastian Korste, Armin Spomer, Ulrike Barbara Hendgen-Cotta, Tienush Rassaf, Matthias Totzeck
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7533 (2022)
The programmed cell death protein 1 (PD1) immune checkpoint prevents inflammatory tissue damage by inhibiting immune reactions. Understanding the relevance of cardiac PD1 signaling may provide new insights into the inflammatory events under baseline
Externí odkaz:
https://doaj.org/article/d8744110f0e2409aafff857aeab3a285
Autor:
Simon F. Merz, Sebastian Korste, Lea Bornemann, Lars Michel, Pia Stock, Anthony Squire, Camille Soun, Daniel R. Engel, Julia Detzer, Holger Lörchner, Dirk M. Hermann, Markus Kamler, Joachim Klode, Ulrike B. Hendgen-Cotta, Tienush Rassaf, Matthias Gunzer, Matthias Totzeck
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/d9923d29d593469cb22f223c62a1ff70
Autor:
Ali A Tuz, Alexander Beer, Markus Gallert, Dimitris Ttoouli, Susmita Ghosh, Sai P Sata, Andreas Kraus, Franziska Zwirnlein, Viola Kaygusuz, Vivian Lakovic, Altea Qefalia, Medina Antler, Sebastian Korste, Britta Kaltwasser, Hossam Abdelrahman, Ayan Mohamud-Yusuf, Chen Wang, Lars Haeusler, Smiths Lueong, Martin Stenzel, Benedikt Frank, Martin Köhrmann, Jens Siveke, Matthias Totzeck, Daniel Hoffmann, Anika Grüneboom, Nina Hagemann, Anja Hasenberg, Albert Sickmann, Jianxu Chen, Dirk M Hermann, Matthias Gunzer, Vikramjeet Singh
Publikováno v:
SSRN Electronic Journal.
SummaryLymphocyte contraction (LC) in central immune organs is a concomitant of sterile tissue injury, for example after stroke. Intestinal Peyer’s patches (PP) harbor large numbers of B cells, but how sterile tissue injury leads to LC in PP has no
Autor:
F Wirsdoerfer, Lars Michel, Sebastian Korste, Matthias Totzeck, Simone M. Mrotzek, V Jendrossek, Ulrike B. Hendgen-Cotta, Tienush Rassaf, L Gockeln
Publikováno v:
European Heart Journal. 42
Background The improvement of anticancer-therapy results in a greater amount of long-term survivors after radiotherapy. Therefore, the understanding of cardiotoxicity after irradiation is of increasing importance. Long-term adverse cardiovascular eve
Autor:
Dirk Schadendorf, Robert Ahrends, Sebastian Korste, Ken Herrmann, Lisa Zimmer, Simone M. Mrotzek, Selma Ugurel, Raluca-Ileana Mincu, Matthias Totzeck, Elisabeth Livingstone, Iris Helfrich, Christoph Rischpler, Tienush Rassaf, Matthias Gunzer, Lars Michel, Andrea Odersky, Albert Sickmann, Cristina Coman, Armin Spomer, Ulrike B. Hendgen-Cotta, Stefanie Löffek, Lale Umutlu
Publikováno v:
European heart journal. 43(4)
Aims Cardiac immune-related adverse events (irAEs) from immune checkpoint inhibition (ICI) targeting programmed death 1 (PD1) are of growing concern. Once cardiac irAEs become clinically manifest, fatality rates are high. Cardio-oncology aims to prev