Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sebastian Kollmann"'
Autor:
Barbara Maurer, Tania Brandstoetter, Sebastian Kollmann, Veronika Sexl, Michaela Prchal-Murphy
Publikováno v:
Haematologica, Vol 106, Iss 10 (2020)
Cyclin-dependent kinases 4 and 6 (CDK4/6) inhibitors are considered a breakthrough in cancer therapy. Currently approved for breast cancer treatment, CDK4/6 inhibitors are extensively tested in other cancer subtypes. Frequently observed side effects
Externí odkaz:
https://doaj.org/article/edf45fff11734d6f82c2a01fb415fe2e
Autor:
Tania Brandstoetter, Johannes Schmoellerl, Reinhard Grausenburger, Sebastian Kollmann, Eszter Doma, Jani Huuhtanen, Thorsten Klampfl, Thomas Eder, Florian Grebien, Gregor Hoermann, Johannes Zuber, Satu Mustjoki, Barbara Maurer, Veronika Sexl
Publikováno v:
Blood. 141:1831-1845
Funding Information: The authors thank Sabine Fajmann, Petra Kudweis, Philipp Jodl, and Isabella Mayer for excellent experimental support. The authors thank the Biomedical Sequencing Facility at the CeMM Research Center for Molecular Medicine at the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d69112764944f4b26be6a26053089156
https://doi.org/10.1182/blood.2022018494
https://doi.org/10.1182/blood.2022018494
Autor:
Sebastian Kollmann
Publikováno v:
Intrinsic Activity. 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a627d006f02b1fb529485299489567c
https://doi.org/10.25006/ia.10.s1-a2.3
https://doi.org/10.25006/ia.10.s1-a2.3
Autor:
Richard Moriggl, Thorsten Klampfl, Peter Valent, Karoline Kollmann, Florian Halbritter, Klavdija Bastl, Matthias Farlik, Veronika Sexl, Tania Brandstoetter, Sebastian Kollmann, Eszter Doma, Gerwin Heller, Sabine Lagger, Wolfgang R. Sperr, Michaela Prchal-Murphy, Reinhard Grausenburger, Vanessa Maria Knab, Hanja Pisa, Barbara Maurer
Publikováno v:
Blood
The transcription factors signal transducer and activator of transcription 5A (STAT5A) and STAT5B are critical in hematopoiesis and leukemia. They are widely believed to have redundant functions, but we describe a unique role for STAT5B in driving th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ace0f8398dc0a3e269d7033e29f7dde2
https://europepmc.org/articles/PMC8777465/
https://europepmc.org/articles/PMC8777465/
Twins with different personalities: STAT5B—but not STAT5A—has a key role in BCR/ABL-induced leukemia
Autor:
Reinhard Grausenburger, Barbara Maurer, Sebastian Kollmann, Andrea Hoelbl-Kovacic, Leo Edlinger, Wolfgang Warsch, Lothar Hennighausen, Sabine Lagger, Jani Huuhtanen, Eva Grundschober, Peter Valent, Birgit Strobl, Veronika Sexl, Satu Mustjoki, Thomas Decker, Mathias Mueller
Publikováno v:
Leukemia
Deregulation of the Janus kinase/signal transducers and activators of transcription (JAK/STAT) signaling pathway is found in cancer with STAT5A/B controlling leukemic cell survival and disease progression. As mutations in STAT5B, but not STAT5A, have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::975a12c1dec933b01fcb0d6d8e9a220e
http://europepmc.org/articles/PMC6755975
http://europepmc.org/articles/PMC6755975
Autor:
André C. Mueller, Stefan Kubicek, Benjamin L. Ebert, Reinhard Grausenburger, Markus Zojer, Veronika Sexl, Gerwin Heller, Anca-Sarmiza Tigan, Claus Vogl, Marlies Dolezal, Karoline Kollmann, Johannes Zuber, Iris Z. Uras, Svenja Hartenberger, Alexander Höllein, Donna Neuberg, Sebastian Kollmann, Marcos Malumbres, Joanna I. Loizou, Eszter Doma, Andreas Villunger, Michaela Prchal-Murphy, Anna Ringler, Florian Bellutti, Sofie Nebenfuehr, Matthias Farlik, Philip W. Hinds
Publikováno v:
Cancer Discovery
Tumor formation is a multi-step process during which cells acquire genetic and epigenetic changes until they reach a fully transformed state. We show that CDK6 contributes to tumor formation by regulating transcriptional responses in a stage-specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03c007fd1cd566c648b4d2716823abbb
https://doi.org/10.1158/2159-8290.cd-17-0912
https://doi.org/10.1158/2159-8290.cd-17-0912
Publikováno v:
Cancers
Cancers, Vol 11, Iss 11, p 1726 (2019)
Cancers, Vol 11, Iss 11, p 1726 (2019)
The transcription factors STAT5A and STAT5B have essential roles in survival and proliferation of hematopoietic cells—which have been considered largely redundant. Mutations of upstream kinases, copy number gains, or activating mutations in STAT5A,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ccc0028303e8cd7f7eec3746af28012
http://europepmc.org/articles/PMC6895831
http://europepmc.org/articles/PMC6895831